SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_015535
Gene Symbol:	SPATS2L
Description:	Homo sapiens spermatogenesis associated, serine-rich 2-like (SPATS2L), transcript variant 2, mRNA.
Gene Location:	chr2(+):201170603-201346986
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.200478912T>C			COSN6932394		8069446		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3148	tctTTTTTCCttttctttt	1	UGGAAAAA	m7b	(m6b->m7b)	0.266000	0.268000	-0.400000

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.200480143A>G			COSN6164056		RK212_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4470	aaaaaatgaGTTTGCCAgg	5	UGGCAAAC	m8a	(m7b->m8a)	0.105000	0.078000	0.260000
hsa-miR-4760-3p	aaaaaATGAATTTgccagg	0	AAAUUCAU	m8a	Disrupted	0.129000	no TS	1.730000
hsa-miR-664-3p	aaaaAATGAATttgccagg	0	UAUUCAUU	m7b	Disrupted	0.095000	no TS	0.020000

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.200482040A>G			COSN6419560		HX11T		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-204-5p	caaaaaAAAGGGAAaaaaa	2	UUCCCUUU	m8a	Created	0.096000	-0.252000	-1.160000
hsa-miR-211-5p	caaaaaAAAGGGAAaaaaa	2	UUCCCUUU	m8a	Created	0.096000	-0.263000	-0.180000
hsa-miR-4446-5p	caaaaaaaAGGGAAAaaaa	2	AUUUCCCU	m7b	Created	0.096000	-0.232000	No effect
hsa-miR-4755-5p	caaaaaaAAGGGAAAaaaa	2	UUUCCCUU	m8a	Created	0.077000	-0.262000	-0.130000
hsa-miR-5006-3p	caaaaaaAAGGGAAAaaaa	2	UUUCCCUU	m8a	Created	0.092000	-0.247000	-0.110000
hsa-miR-623	caaaaaaAAGGGAaaaaaa	3	AUCCCUUG	m6b	Created	0.043000	-0.107000	-2.120000

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.200482042G>A			COSN1231658		HX11T		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
200481683	rs191604158	G	G	hsa-miR-3120-3p hsa-miR-3613-3p hsa-miR-545-3p hsa-miR-548p	1 2 1 1	ttttTTGCTGTAc TTTTTTGctgtac tttTTTGCTGtac ttTTTTGCTgtac	Disrupted Disrupted Disrupted Disrupted	N N N N	-0.169 0.136 -0.074 -0.029
			C	hsa-miR-3148 hsa-miR-4700-3p	2 1	tTTTTTCCtgtac tttttTCCTGTAc	Created Created	N N	0.008 -0.064

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