SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
  Home Search Help Download  

PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_017508
Gene Symbol: SOX6
Description: Homo sapiens SRY (sex determining region Y)-box 6 (SOX6), transcript variant 3, mRNA.
Gene Location: chr11(-):15987994-16424413
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr11:g.15966583G>A COSN4720228 tumor_4177434 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4639-3p ccccttagGAGAGTGtcta
 0 UCACUCUC m7b Created no TS -0.170000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.15966674T>- ICGC_ssm_v2_88532 HX13T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3148 tttttTTTTTCCtttttgc
 0 UGGAAAAA m7b Disrupted -0.046000 -0.042000 5.100000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.15966982C>A COSN5901944 RK193_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4693-3p tctttctcaCACTCTCctc
 13
 UGAGAGUG m7b (m7b->m6b) -0.167000 no TS 2.560000
hsa-miR-574-5p tctttctCACACTCtcctc
 12
 UGAGUGUG m7b Disrupted -0.324000 -0.107000 No effect
hsa-miR-580 tctTTCTCAAactctcctc
 7
 UUGAGAAU m7a (m6b->m7a) 0.007000 -0.024000 0.240000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.15967016A>C COSN8740350 AOCS-106-1-1 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4495 aagttTTTACATgacctta
 0 AAUGUAAA m7b Created no TS -0.054000 No effect
hsa-miR-5696 aagttttTAAATGAcctta
 16
 CUCAUUUA m7b Disrupted 0.337000 0.340000 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.15967175T>C COSN5258752 HX28T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1271-3p taatgCAGGCACctacttg
 0 AGUGCCUG m7b Created no TS -0.144000 -0.070000
hsa-miR-4763-5p taatGCAGGCacctacttg
 0 CGCCUGCC m6b Created no TS -0.134000 No effect
hsa-miR-550a-3-5p taatgCAGGCACctacttg
 0 AGUGCCUG m7b Created no TS -0.153000 -0.090000
hsa-miR-550a-5p taatgCAGGCACctacttg
 0 AGUGCCUG m7b Created no TS -0.153000 -0.010000


Mutation Mutation ID Sample Name Cancer Type
chr11:g.15967904G>A COSN8534244 tumor_4120193 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr11:g.15968097T>C COSN6406514 HX20T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1207-5p gtctgttatCCCTGCCAat
 2
 UGGCAGGG m8a (m7a->m8a) -0.089000 -0.211000 -2.290000
hsa-miR-4722-5p gtctgttatTCCTGCCaat
 0 GGCAGGAG m7a (m7a->m6a) NA NA 0.010000
hsa-miR-4763-3p gtctgttatCCCTGCCaat
 2
 AGGCAGGG m7b (m6b->m7b) -0.096000 -0.197000 -0.120000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.15968212T>A COSN1129731 HX13T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-126-5p ttctcaaagAATAATaata
 0 CAUUAUUA m6b Created 0.362000 0.514000 No effect
hsa-miR-4795-3p ttctcaaagAATAATAata
 0 AUAUUAUU m7b (m6b->m7b) 0.373000 0.516000 No effect
hsa-miR-126-5p ttctcaaagAATAATaata
 0 CAUUAUUA m6b Created 0.362 0.514 No effect
hsa-miR-4795-3p ttctcaaagAATAATAata
 0 AUAUUAUU m7b (m6b->m7b) 0.373 0.516 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.15968257C>G COSN8941384 SS6003320 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3177-5p tttTGTACACgtttgtcta
 7
 UGUGUACA m7b (m7b->m6c) -0.043000 no TS 0.100000
hsa-miR-486-5p ttttGTACAGGtttgtcta
 1
 UCCUGUAC m7b Created -0.154000 -0.243000 -0.010000
hsa-miR-649 ttttgtACAGGTTTgtcta
 19
 AAACCUGU m8a Created -0.083000 -0.115000 -0.290000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.15969324T>G COSN5300418 RK085_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3074-5p caagaaGCAGGAAtgccac
 1
 GUUCCUGC m7b Created 0.083000 0.074000 -0.010000
hsa-miR-370 caagaAGCAGGaatgccac
 0 GCCUGCUG m6b Created no TS 0.001000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.15970460C>T COSN8641253 4400_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3925-5p ttgcttttGTTCTCTctca
 11
 AAGAGAAC m7b Created -0.025000 -0.045000 -4.520000
hsa-miR-548aj-5p ttgCTTTTGCtctctctca
 13
 UGCAAAAG m7b (m7b->m6c) 0.378000 0.284000 0.370000
hsa-miR-548g-5p ttgCTTTTGCtctctctca
 13
 UGCAAAAG m7b (m7b->m6c) 0.378000 0.284000 0.370000
hsa-miR-548p ttgcTTTTGCTctctctca
 17
 UAGCAAAA m7b Disrupted 0.234000 0.086000 No effect
hsa-miR-548x-5p ttgCTTTTGCtctctctca
 13
 UGCAAAAG m7b (m7b->m6c) 0.378000 0.284000 0.370000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.15971984C>T COSN8217036 PCSI_0083_Pa_P_526 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-34c-5p cagagcaACTGCCacacca
 2
 AGGCAGUG m6b Created -0.024000 -0.067000 -1.130000
hsa-miR-3688-5p cagagcaacTGCCACacca
 14
 AGUGGCAA m6b Created -0.187000 -0.266000 -0.990000
hsa-miR-449b-5p cagagcaACTGCCacacca
 2
 AGGCAGUG m6b Created -0.047000 -0.097000 -0.620000
hsa-miR-548au-3p cagagcAACTGCCAcacca
 16
 UGGCAGUU m8a Created -0.242000 -0.368000 -0.350000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.15972540C>G COSN8534245 tumor_4120193 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3942-3p aacttATCTGAAcccgtag
 19
 UUUCAGAU m7b Created -0.009000 -0.104000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.15972597T>G COSN8217037 PCSI_0002_Pa_P [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3529-3p gttgTTGTTGTTttaattt
 10
 AACAACAA m8a Created -0.683000 -0.778000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.15972676T>A COSN5901945 RK207_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-342-3p ttcgtaaaGTGTGAGAcag
 18
 UCUCACAC m8a Disrupted -0.401000 no TS 1.120000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Genome Browser