SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_134270
Gene Symbol: SMTN
Description: Homo sapiens smoothelin (SMTN), transcript variant 4, mRNA.
Gene Location: chr22(+):31477281-31500610
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr22:g.31104477C>T COSN5770777 CCC64 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3937 ctgcCCGCCTGcatggcca
 0 ACAGGCGG m7b Created no TS 0.000000 -0.170000
hsa-miR-4767 ctgccCGCCCGCatggcca
 0 CGCGGGCG m7b Disrupted 0.000000 no TS -1.070000
hsa-miR-3937 ctgcCCGCCTGcatggcca
 0 ACAGGCGG m7b Created no TS 0.000000 -0.170000
hsa-miR-4767 ctgccCGCCCGCatggcca
 0 CGCGGGCG m7b Disrupted 0.000000 no TS -1.070000

Mutation Mutation ID Sample Name Cancer Type
chr22:g.31104550G>A COSN6692630 CHC433T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-34a-5p ccgcccacCACTGCCctgt
 0 UGGCAGUG m7b Created no TS -0.132000 -1.520000
hsa-miR-34c-5p ccgcccacCACTGCCctgt
 0 AGGCAGUG m7b Created no TS -0.132000 -3.640000
hsa-miR-449a ccgcccacCACTGCCctgt
 0 UGGCAGUG m7b Created no TS -0.123000 -2.240000
hsa-miR-449b-5p ccgcccacCACTGCCctgt
 0 AGGCAGUG m7b Created no TS -0.123000 -2.380000
hsa-miR-541-3p ccGCCCACCActgccctgt
 8
 UGGUGGGC m8a (m7a->m8a) -0.132000 -0.357000 -3.350000
hsa-miR-654-5p ccGCCCACCActgccctgt
 8
 UGGUGGGC m8a (m7a->m8a) -0.151000 -0.378000 -3.340000
hsa-miR-885-3p ccgcccacCGCTGCCctgt
 6
 AGGCAGCG m7b Disrupted -0.174000 no TS 1.980000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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