SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_134269
Gene Symbol:	SMTN
Description:	Homo sapiens smoothelin (SMTN), transcript variant 4, mRNA.
Gene Location:	chr22(+):31477281-31500610
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr22:g.31104348A>A			ICGC_45349		TCGA-CF-A3MF-01A-12D-A21A-08		BladderUrothelialCarcinoma(TCGA,US)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1306-5p	tggtGGAGGTGGacgacat	0	CCACCUCC	m8a	Disrupted	-0.192	no TS	8.08
hsa-miR-5193	tggtgGAGGAGGAcgacat	0	UCCUCCUC	m8a	Created	no TS	-0.329	-10.8

Mutation			Mutation ID		Sample Name		Cancer Type
chr22:g.31104444G>A			ICGC_1451298		TCGA-A5-A0VP-01A-21D-A10B-09		UterineCorpusEndometrioidCarcinoma(TCGA,US)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-143-5p	acgaACTGCACCtgcgcgg	0	GGUGCAGU	m8a	Created	no TS	-0.112	-4.78
hsa-miR-3665	acgaactgCACCTGCgcgg	0	AGCAGGUG	m7b	Created	-0.151	-0.29	-2.6
hsa-miR-764	acgaactGCACCTGCgcgg	0	GCAGGUGC	m8a	Created	no TS	-0.147	-3.9

Mutation			Mutation ID		Sample Name		Cancer Type
chr22:g.31104457G>C			ICGC_1451299		TCGA-B5-A11R-01A-11D-A122-09		UterineCorpusEndometrioidCarcinoma(TCGA,US)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4423-5p	gcgcGGCAACaatgtctag	0	AGUUGCCU	m6b	Created	no TS	-0.111	0.14
hsa-miR-744-3p	gcgcGGCAACAatgtctag	0	CUGUUGCC	m7b	Created	no TS	-0.23	-3.55

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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