SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001112802
Gene Symbol: SLC8A1
Description: Homo sapiens solute carrier family 8 (sodium/calcium exchanger), member 1 (SLC8A1), transcript variant B, mRNA.
Gene Location: chr2(-):40339285-40739575
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr2:g.40112209T>C COSN10000183 C0021T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3150b-3p tttTCTCCTCtctcattgt
 4
 UGAGGAGA m7b (m6c->m7b) -0.010000 -0.254000 -1.630000
hsa-miR-4428 tttTCTCCTTtctcattgt
 0 CAAGGAGA m7b (m7b->m6c) -0.272000 no TS 0.010000
hsa-miR-4712-3p ttttctcctCTCTCATTgt
 0 AAUGAGAG m8a (m7a->m8a) no TS -0.206000 -1.380000
hsa-miR-4784 tttTCTCCTCtctcattgt
 4
 UGAGGAGA m7b (m6c->m7b) -0.019000 -0.263000 -2.580000
hsa-miR-539-5p ttttctccTTTCTCattgt
 2
 GGAGAAAU m6b Disrupted -0.060000 no TS 0.050000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.40112280A>T COSN8609211 4095_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4288 acaCAGACAAataaagttt
 0 UUGUCUGC m7a (m7a->m6b) -0.152000 no TS -0.010000
hsa-miR-654-3p acaCAGACATAtaaagttt
 8
 UAUGUCUG m8a Created 0.014000 -0.366000 -0.720000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.40112659->T ICGC_sm100013 RK015_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3613-3p ttttTTTTTTGagaattgc
 0 ACAAAAAA m7b Disrupted -0.014000 -0.016000 No effect
hsa-miR-371a-5p tttttttTTTGAGaattgc
 0 ACUCAAAC m6b Disrupted -0.019000 -0.020000 No effect
hsa-miR-371b-5p ttttttTTTTGAGaattgc
 0 ACUCAAAA m7b Disrupted 0.026000 0.025000 -0.010000
hsa-miR-373-5p ttttttTTTTGAGaattgc
 0 ACUCAAAA m7b Disrupted 0.035000 0.034000 -0.040000
hsa-miR-616-5p ttttttTTTTGAGaattgc
 0 ACUCAAAA m7b Disrupted 0.016000 0.015000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.40112659->TT ICGC_ssm_v2_10981 HX5T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3613-3p tttttTTTTTTGagaattgct
 0 ACAAAAAA m7b Disrupted -0.014000 -0.018000 No effect
hsa-miR-371a-5p ttttttttTTTGAGaattgct
 0 ACUCAAAC m6b Disrupted -0.019000 -0.022000 No effect
hsa-miR-371b-5p tttttttTTTTGAGaattgct
 0 ACUCAAAA m7b Disrupted 0.026000 0.022000 -0.080000
hsa-miR-373-5p tttttttTTTTGAGaattgct
 0 ACUCAAAA m7b Disrupted 0.035000 0.031000 -0.220000
hsa-miR-616-5p tttttttTTTTGAGaattgct
 0 ACUCAAAA m7b Disrupted 0.016000 0.012000 -0.020000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.40113273G>C COSN9373396 AOCS-088-3-8 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-15b-3p ctctgtatTGATTCaaaaa
 0 CGAAUCAU m6b Disrupted -0.134000 -0.133000 0.380000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.40113386C>G COSN8993317 8057646 [pancreas][NS][carcinoid-endocrine_tumour][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1 ccaACATTCCAaagtagtg
 0 UGGAAUGU m8a Disrupted -0.014000 0.031000 0.260000
hsa-miR-206 ccaACATTCCAaagtagtg
 0 UGGAAUGU m8a Disrupted -0.004000 0.031000 0.220000
hsa-miR-3673 ccaaCATTCCAaagtagtg
 8
 AUGGAAUG m7b Disrupted -0.034000 no TS 0.050000
hsa-miR-613 ccaACATTCCaaagtagtg
 0 AGGAAUGU m7b (m7b->m6c) -0.025000 0.031000 0.260000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.40113518A>G COSN7128644 8016470 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-125b-2-3p cctctACTTGTGctgaaag
 0 UCACAAGU m7b Created no TS 0.029000 -0.520000
hsa-miR-3065-3p cctctacttGTGCTGAaag
 0 UCAGCACC m7a (m6a->m7a) no TS -0.025000 -4.270000
hsa-miR-4310 cctctacttATGCTGaaag
 7
 GCAGCAUU m6b Disrupted -0.048000 -0.065000 0.860000
hsa-miR-5697 cctCTACTTGtgctgaaag
 0 UCAAGUAG m7b (m6c->m7b) no TS 0.036000 -0.830000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.40113558G>A COSN1839394 RK025_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3620 agaagcCAGGGTGAccaac
 4
 UCACCCUG m8a Disrupted -0.011000 no TS No effect
hsa-miR-514a-5p agaagCCAGAGTgaccaac
 0 UACUCUGG m7b Created no TS 0.018000 No effect
hsa-miR-668 agaagccaGAGTGACcaac
 0 UGUCACUC m7b Created no TS -0.010000 -7.490000
hsa-miR-3620 agaagcCAGGGTGAccaac
 4
 UCACCCUG m8a Disrupted -0.011000 no TS No effect
hsa-miR-514a-5p agaagCCAGAGTgaccaac
 0 UACUCUGG m7b Created no TS 0.018000 No effect
hsa-miR-668 agaagccaGAGTGACcaac
 0 UGUCACUC m7b Created no TS -0.010000 -7.490000
hsa-miR-3620 agaagcCAGGGTGAccaac
 0 UCACCCUG m8a Disrupted -0.011 no TS No effect
hsa-miR-514a-5p agaagCCAGAGTgaccaac
 0 UACUCUGG m7b Created no TS 0.018 No effect
hsa-miR-668 agaagccaGAGTGACcaac
 0 UGUCACUC m7b Created no TS -0.01 -7.49

Mutation Mutation ID Sample Name Cancer Type
chr2:g.40113882A>G COSN1839395 RK056_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-20b-3p caaACTACAGagatcttca
 0 ACUGUAGU m7b (m6c->m7b) no TS -0.008000 -2.420000
hsa-miR-3674 caaaCTACAAagatcttca
 5
 AUUGUAGA m6b Disrupted 0.065000 no TS No effect
hsa-miR-20b-3p caaACTACAGagatcttca
 0 ACUGUAGU m7b (m6c->m7b) no TS -0.008 -2.42
hsa-miR-3674 caaaCTACAAagatcttca
 0 AUUGUAGA m6b Disrupted 0.065 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.40114112A>G COSN6181335 RK308_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-625-3p gtagagTATAGTacatact
 11
 GACUAUAG m6b Disrupted 0.114000 0.084000 0.530000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.40114293G>C COSN9373397 AOCS-112-1-2 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4480 gttgCTTGGCattgtctgt
 0 AGCCAAGU m6b Created no TS -0.071000 -0.010000
hsa-miR-4733-5p gttgcTTGGGATTgtctgt
 0 AAUCCCAA m8a Disrupted -0.031000 -0.031000 4.160000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.40115087C>A COSN5503613 RK155_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1 catcacctcACATTCCcag
 0 UGGAAUGU m7b (m6b->m7b) -0.014000 -0.086000 -0.910000
hsa-miR-1294 catcACCTCACAttcccag
 0 UGUGAGGU m8a Created no TS -0.354000 -2.660000
hsa-miR-149-3p catcaCCTCCCattcccag
 7
 AGGGAGGG m6b Disrupted -0.170000 -0.031000 No effect
hsa-miR-206 catcacctcACATTCCcag
 0 UGGAAUGU m7b (m6b->m7b) -0.004000 -0.085000 -0.320000
hsa-miR-30b-3p catcaCCTCCCAttcccag
 7
 CUGGGAGG m7b Disrupted -0.299000 -0.055000 3.480000
hsa-miR-3689a-3p catcaCCTCCCAttcccag
 7
 CUGGGAGG m7b Disrupted -0.290000 -0.055000 0.290000
hsa-miR-3689b-3p catcaCCTCCCAttcccag
 7
 CUGGGAGG m7b Disrupted -0.300000 -0.065000 0.050000
hsa-miR-3689c catcaCCTCCCAttcccag
 7
 CUGGGAGG m7b Disrupted -0.300000 -0.065000 0.050000
hsa-miR-3689d catCACCTCCCattcccag
 7
 GGGAGGUG m8a Disrupted -0.388000 -0.159000 0.070000
hsa-miR-4316 catcaCCTCACattcccag
 0 GGUGAGGC m6b Created no TS -0.156000 -0.120000
hsa-miR-613 catcacctcACATTCCcag
 0 AGGAAUGU m7b (m6b->m7b) -0.025000 -0.097000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.40115237T>G COSN1839396 RK092_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5684 tatcagaTAGAGTaaattt
 14
 AACUCUAG m6b Created -0.044000 -0.088000 No effect
hsa-miR-625-3p tatcagaTATAGTaaattt
 11
 GACUAUAG m6b Disrupted 0.114000 0.076000 No effect
hsa-miR-5684 tatcagaTAGAGTaaattt
 0 AACUCUAG m6b Created -0.044 -0.088 No effect
hsa-miR-625-3p tatcagaTATAGTaaattt
 0 GACUAUAG m6b Disrupted 0.114 0.076 No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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