SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_001145098
Gene Symbol:	SKIL
Description:	Homo sapiens SKI-like oncogene (SKIL), transcript variant 2, mRNA.
Gene Location:	chr3(+):170075472-170110950
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.170392512G>A			COSN1271799		BN37T		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-491-3p	tatcTGCATAAcgataact	0	CUUAUGCA	m7b	Created	no TS	-0.161000	No effect
hsa-miR-491-3p	tatcTGCATAAcgataact	0	CUUAUGCA	m7b	Created	no TS	-0.161	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.170393158C>T			COSN7626575		PCSI_0112_Pa_P		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3613-3p	tgataaTTTTTGaactttt	0	ACAAAAAA	m6b	Created	0.450000	0.539000	No effect
hsa-miR-5000-5p	tgataatttCTGAACTttt	0	CAGUUCAG	m7b	(m7b->m6c)	-0.154000	0.026000	0.180000
hsa-miR-548c-3p	tgataATTTTTGaactttt	0	CAAAAAUC	m7a	Created	0.929000	0.929000	-0.350000

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.170393533A>T			COSN6753123		RK119_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-141-5p	aagttttaGAAGATaaagg	0	CAUCUUCC	m6b	Disrupted	-0.047000	-0.050000	No effect
hsa-miR-4799-5p	aagtTTTAGAagataaagg	0	AUCUAAAU	m6b	Disrupted	0.574000	0.491000	0.100000

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.170394830G>T			COSN5527755		RK090_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-216b	aacaatatAGAGATTTtgt	0	AAAUCUCU	m8a	Disrupted	0.000000	0.000000	5.230000
hsa-miR-3675-3p	aacaataTAGAGATtttgt	0	CAUCUCUA	m7b	Disrupted	-0.013000	no TS	1.950000

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.170395192A>T			COSN7834917		8069120		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4724-3p	tactctataAAGGTAataa	0	GUACCUUC	m6b	Disrupted	-0.126000	-0.137000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr3:g.170396116C>A			COSN9532982		AOCS-138-3-X		[ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-374b-3p	gtagTGCTAAaatttttga	0	CUUAGCAG	m6b	Created	-0.184000	-0.259000	No effect
hsa-miR-4282	gtagtgctaAAATTTTtga	0	UAAAAUUU	m7b	(m6c->m7b)	1.513000	1.585000	-0.010000
hsa-miR-5682	gtaGTGCTACaatttttga	0	GUAGCACC	m7a	(m7a->m6a)	no TS	-0.147000	-0.340000
hsa-miR-590-3p	gtagtgcTAAAATTtttga	0	UAAUUUUA	m7b	Created	0.526000	0.636000	-0.010000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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