SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_145060 |
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Gene Symbol: | SKA1 |
Description: | Homo sapiens spindle and kinetochore associated complex subunit 1 (SKA1), transcript variant 1, mRNA. |
Gene Location: | chr18(+):47901391-47920538 |
Browse Associations |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr18:g.50392347G>T | COSN1206889 | HCC109T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3148 |
atctttttTTTTTCCtttt |
0 | UGGAAAAA | m7b | Created | no TS | -0.156000 |
-0.010000 |
hsa-miR-3613-3p |
atcTTTTTTGTttcctttt |
1 |
ACAAAAAA | m8a | Disrupted | 0.041000 | 0.093000 |
-0.290000 |
hsa-miR-4261 |
atctttttTGTTTCCTttt |
0 | AGGAAACA | m8a | Disrupted | -0.254000 | no TS |
0.450000 |
hsa-miR-4496 |
atcttttttGTTTCCTttt |
0 | GAGGAAAC | m7b | (m7b->m6c) | -0.270000 | no TS |
2.770000 |
hsa-miR-3148 |
atctttttTTTTTCCtttt |
0 | UGGAAAAA | m7b | Created | no TS | -0.156 |
-0.01 |
hsa-miR-3613-3p |
atcTTTTTTGTttcctttt |
0 | ACAAAAAA | m8a | Disrupted | 0.041 | 0.093 |
-1.1 |
hsa-miR-4261 |
atctttttTGTTTCCTttt |
0 | AGGAAACA | m8a | Disrupted | -0.254 | no TS |
0.45 |
hsa-miR-4496 |
atcttttttGTTTCCTttt |
0 | GAGGAAAC | m7b | (m7b->m6c) | -0.27 | no TS |
2.77 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr18:g.50392367G>T | COSN6416503 | HCC117T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3613-3p |
tttTTTTTTGagacaggat |
1 |
ACAAAAAA | m7b | (m7b->m6b) | 0.041000 | 0.103000 |
-0.300000 |
hsa-miR-371a-5p |
ttttttTTTGAGacaggat |
2 |
ACUCAAAC | m6b | Disrupted | -0.040000 | 0.006000 |
1.250000 |
hsa-miR-371b-5p |
tttttTTTTGAGacaggat |
2 |
ACUCAAAA | m7b | Disrupted | -0.244000 | -0.061000 |
3.760000 |
hsa-miR-373-5p |
tttttTTTTGAGacaggat |
2 |
ACUCAAAA | m7b | Disrupted | -0.223000 | -0.061000 |
3.660000 |
hsa-miR-616-5p |
tttttTTTTGAGacaggat |
2 |
ACUCAAAA | m7b | Disrupted | -0.276000 | -0.082000 |
1.030000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr18:g.50392619T>A | COSN7361598 | 8066452 | [pancreas][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3929 |
ccaccctccTCAGCCTCcc |
1 |
GAGGCUGA | m8a | (m8a->m7b) | -0.082000 | -0.016000 |
0.030000 |
hsa-miR-4419b |
ccaccctccTCAGCCTCcc |
1 |
GAGGCUGA | m8a | (m8a->m7b) | -0.100000 | -0.034000 | No effect |
hsa-miR-4478 |
ccaccctccTCAGCCTCcc |
1 |
GAGGCUGA | m8a | (m8a->m7b) | -0.137000 | -0.053000 | No effect |
hsa-miR-4689 |
ccaccCTCCTCAgcctccc |
1 |
UUGAGGAG | m7b | Disrupted | -0.092000 | no TS | No effect |
hsa-miR-4779 |
ccaCCCTCCTcagcctccc |
1 |
UAGGAGGG | m7b | (m7b->m6b) | -0.160000 | no TS | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr18:g.50392852C>T | COSN8343444 | 0007_CRUK_PC_0007_T3_DNA | [prostate][NS][carcinoma][adenocarcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3154 |
cctcagCCTTCTGagtagc |
0 | CAGAAGGG | m7a | Created | NA | NA |
-0.710000 |
hsa-miR-3664-3p |
cctcagccTCCTGAGtagc |
0 | UCUCAGGA | m7b | Disrupted | -0.160000 | -0.135000 |
0.770000 |
hsa-miR-3929 |
ccTCAGCCTCctgagtagc |
1 |
GAGGCUGA | m8a | (m8a->m7a) | -0.082000 | -0.109000 |
0.010000 |
hsa-miR-4419b |
ccTCAGCCTCctgagtagc |
1 |
GAGGCUGA | m8a | (m8a->m7a) | -0.100000 | -0.127000 |
0.240000 |
hsa-miR-4433-3p |
cctcagcCTCCTGagtagc |
1 |
ACAGGAGU | m6b | Disrupted | -0.113000 | -0.085000 |
0.130000 |
hsa-miR-4459 |
cctcagCCTCCTGagtagc |
1 |
CCAGGAGG | m7b | Disrupted | -0.357000 | -0.164000 |
0.600000 |
hsa-miR-4478 |
ccTCAGCCTCctgagtagc |
1 |
GAGGCUGA | m8a | (m8a->m7a) | -0.137000 | -0.164000 |
0.230000 |
hsa-miR-4695-5p |
cctcaGCCTCCTGagtagc |
0 | CAGGAGGC | m8a | Disrupted | -0.140000 | no TS |
0.020000 |
hsa-miR-4768-3p |
cctcagcCTCCTGagtagc |
1 |
CCAGGAGA | m6b | Disrupted | -0.258000 | -0.233000 |
0.010000 |
hsa-miR-485-5p |
cctCAGCCTCctgagtagc |
1 |
AGAGGCUG | m7b | (m7b->m6b) | -0.537000 | -0.447000 |
0.020000 |
hsa-miR-510 |
cctcagcctCCTGAGTAgc |
0 | UACUCAGG | m8a | (m8a->m7b) | -0.198000 | -0.020000 |
2.720000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr18:g.50392867C>T | ICGC_8D9BC1C0-2A78-11E2-96E7-04FD496BB9B8 | CPCG_0102_Pr_P_P1 | ProstateCancer(OICR,CA) | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-20b-3p |
tagctgggACTACAGgcac |
0 | ACUGUAGU | m7b | Disrupted | 0.022 | no TS | No effect |
hsa-miR-4733-5p |
tagcTGGGATTacaggcac |
0 | AAUCCCAA | m7a | Created | NA | NA | No effect |
hsa-miR-5588-3p |
tagcTGGGACTacaggcac |
1 |
AAGUCCCA | m7b | Disrupted | -0.451 | -0.271 |
0.02 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr18:g.50392981G>A | ICGC_B0A40A60-2A78-11E2-8335-12FD496BB9B8 | CPCG_0102_Pr_P_P2 | ProstateCancer(OICR,CA) | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3929 |
gcccaccTCAGCCTCccaa |
0 | GAGGCUGA | m8a | Created | -0.082 | -0.066 |
-3.28 |
hsa-miR-4419b |
gcccaccTCAGCCTCccaa |
0 | GAGGCUGA | m8a | Created | -0.1 | -0.103 | No effect |
hsa-miR-4478 |
gcccaccTCAGCCTCccaa |
0 | GAGGCUGA | m8a | Created | -0.137 | -0.149 |
-0.06 |
hsa-miR-485-5p |
gcccacctCAGCCTCccaa |
0 | AGAGGCUG | m7b | Created | -0.537 | -0.609 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr18:g.50393005A>T | COSN1745671 | RK184_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr18:g.50393282T>C | ICGC_8D9BC698-2A78-11E2-96E7-04FD496BB9B8 | CPCG_0102_Pr_P_P1 | ProstateCancer(OICR,CA) | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3135b |
gcaCTCCAGCCtgggcaac |
0 | GGCUGGAG | m8a | Created | -0.23 | -0.333 | No effect |
hsa-miR-3652 |
gcacTCCAGCCtgggcaac |
0 | CGGCUGGA | m7b | Created | no TS | -0.039 | No effect |
hsa-miR-4430 |
gcacTCCAGCCTgggcaac |
0 | AGGCUGGA | m8a | Created | no TS | -0.029 | No effect |
hsa-miR-4463 |
gcactCCAGTCTgggcaac |
1 |
GAGACUGG | m7b | Disrupted | -0.292 | -0.243 | No effect |
hsa-miR-4494 |
gcactcCAGTCTGGgcaac |
1 |
CCAGACUG | m8a | Disrupted | -0.135 | -0.146 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr18:g.50393807G>A | COSN14959567 | LP6005409-DNA_G03 | [oesophagus][NS][carcinoma][adenocarcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr18:g.50394003G>T | COSN6125865 | RK205_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-345-3p |
agcTTCAGGGttggcaaac |
2 |
GCCCUGAA | m7b | (m7b->m6b) | -0.423000 | -0.302000 | No effect |