SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_014521
Gene Symbol:	SH3BP4
Description:	Homo sapiens SH3-domain binding protein 4 (SH3BP4), mRNA.
Gene Location:	chr2(+):235860627-235964358
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.235054051A>G			COSN6175046		RK210_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-513a-3p	taagtatAAATTTAaattt	9	UAAAUUUC	m7a	Disrupted	0.076000	0.049000	0.860000
hsa-miR-513c-3p	taagtatAAATTTAaattt	9	UAAAUUUC	m7a	Disrupted	0.076000	0.049000	0.330000

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.235054690C>T			COSN7240445		8036161		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-186-5p	tgttttTTCTTTGaggtca	0	CAAAGAAU	m7a	Created	0.112000	0.112000	No effect
hsa-miR-3148	tgtTTTTTCCttgaggtca	11	UGGAAAAA	m7b	(m7b->m6b)	-0.030000	-0.078000	No effect
hsa-miR-561-5p	tgtttttTCCTTGAggtca	0	AUCAAGGA	m7b	Disrupted	-0.112000	no TS	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.235055002G>T			COSN6681610		CHC433T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3662	gcaagatgaTCATTTTgta	0	GAAAAUGA	m7b	(m6c->m7b)	no TS	0.025000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.235055163A>G			COSN7240446		8069319		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-29a-5p	tggcAAATCAGTagagtga	2	ACUGAUUU	m8a	Disrupted	0.036000	0.012000	No effect
hsa-miR-3920	tggcaAATCAGTagagtga	2	ACUGAUUA	m7a	Disrupted	0.069000	0.069000	1.550000

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.235055246C>A			COSN5500297		RK143_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3145-3p	atcccgAATATCattctct	0	AGAUAUUU	m6b	Created	no TS	0.031000	-0.020000
hsa-miR-5186	atcccgAATCTCattctct	6	AGAGAUUG	m6b	Disrupted	-0.048000	-0.011000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.235055663G>T			COSN8990311		AOCS-091-1-3		[ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-603	taAGTGTGTGtgtgttttc	0	CACACACU	m8a	(m8a->m7a)	-0.225000	-0.252000	1.580000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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