| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_001145415 |
|---|---|
| Gene Symbol: | SETDB1 |
| Description: | Homo sapiens SET domain, bifurcated 1 (SETDB1), transcript variant 1, mRNA. |
| Gene Location: | chr1(+):150898814-150937220 |
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| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr1:g.150964626G>C | COSN8336418 | 0008_CRUK_PC_0008_T2_DNA | [prostate][NS][carcinoma][adenocarcinoma] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-1270 |
cccatattTCTCCAagtgt |
2 |
CUGGAGAU | m6b | Created | -0.247000 | -0.378000 |
-6.260000 |
| hsa-miR-432-5p |
cccatatttCTCCAAGtgt |
0 | UCUUGGAG | m7b | (m6c->m7b) | no TS | -0.223000 |
-3.550000 |
| hsa-miR-4434 |
cccatatTTCTCCaagtgt |
3 |
AGGAGAAG | m6b | Created | -0.152000 | -0.244000 |
-5.560000 |
| hsa-miR-4516 |
cccatatTTCTCCaagtgt |
3 |
GGGAGAAG | m6b | Created | -0.184000 | -0.286000 |
-3.110000 |
| hsa-miR-4520b-3p |
cccatattTGTCCAAgtgt |
2 |
UUUGGACA | m7b | Disrupted | -0.191000 | no TS |
11.500000 |
| hsa-miR-4531 |
cccatatTTCTCCAagtgt |
3 |
AUGGAGAA | m7b | Created | -0.054000 | -0.358000 |
-0.200000 |
| hsa-miR-539-5p |
cccatATTTCTCCaagtgt |
0 | GGAGAAAU | m8a | Created | no TS | -0.083000 |
-6.290000 |
| hsa-miR-5703 |
cccatatTTCTCCaagtgt |
3 |
AGGAGAAG | m6b | Created | -0.194000 | -0.296000 |
-5.640000 |
| hsa-miR-620 |
cccatattTCTCCAagtgt |
2 |
AUGGAGAU | m6b | Created | -0.247000 | -0.382000 |
-1.150000 |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 150964404 | rs201661003 | C | C |
hsa-miR-3915 hsa-miR-3928-3p hsa-miR-4496 hsa-miR-544b |
9 9 2 12 |
tcgtTTCCTCAgg tcgtTTCCTCAgg tcGTTTCCTcagg tcgtttCCTCAGG |
Disrupted Disrupted Disrupted Disrupted |
N N N N |
-0.136 -0.081 -0.076 -0.294 |
| T |
hsa-miR-4251 hsa-miR-4324 hsa-miR-539-5p hsa-miR-548ad |
10 12 9 2 |
tcgttTTCTCAGg tcgtttTCTCAGG tcgtTTTCTCAgg TCGTTTTctcagg |
Created Created Created Created |
N N N N |
-0.148 -0.257 -0.01 -0.087 |