SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_153616
Gene Symbol: SEMA6D
Description: Homo sapiens sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (SEMA6D), transcript variant 7, mRNA.
Gene Location: chr15(+):48010685-48066420
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr15:g.47771810G>T COSN5398008 RK088_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4422 ttcccatgtTGCTTTatcc
 19
 AAAAGCAU m6b Created -0.258000 -0.318000 -1.550000
hsa-miR-449b-3p ttcccaTGTGGCTttatcc
 16
 CAGCCACA m7b Disrupted -0.244000 no TS 4.380000
hsa-miR-4717-3p ttcCCATGTGgctttatcc
 7
 ACACAUGG m7b (m7b->m6b) -0.130000 0.022000 0.330000

Mutation Mutation ID Sample Name Cancer Type
chr15:g.47771811G>T COSN5398009 RK088_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3617 tcccatgTGTCTTTatcct
 0 AAAGACAU m7a Created NA NA -0.240000
hsa-miR-449b-3p tcccaTGTGGCTttatcct
 16
 CAGCCACA m7b Disrupted -0.244000 no TS 4.380000
hsa-miR-4643 tccCATGTGTCtttatcct
 0 GACACAUG m8a Created -0.328000 -0.454000 No effect
hsa-miR-4717-3p tcCCATGTGTctttatcct
 7
 ACACAUGG m8a (m7a->m8a) -0.130000 -0.159000 -1.200000
hsa-miR-548u tcccatgtGTCTTTatcct
 0 CAAAGACU m6b Created no TS -0.054000 -0.020000
hsa-miR-641 tcccatgTGTCTTTatcct
 0 AAAGACAU m7a Created NA NA -5.030000
hsa-miR-642a-3p tcccATGTGTCTttatcct
 0 AGACACAU m8a Created no TS -0.148000 -1.110000
hsa-miR-642b-3p tcccATGTGTCTttatcct
 0 AGACACAU m8a Created no TS -0.148000 -1.250000


Mutation Mutation ID Sample Name Cancer Type
chr15:g.47771869G>T COSN8745544 AOCS-119-3-9 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr15:g.47772175T>A COSN1677699 RK027_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5580-3p acattttaATATGTatgca
 13
 CACAUAUG m6b Disrupted -0.059000 -0.048000 No effect
hsa-miR-5580-3p acattttaATATGTatgca
 0 CACAUAUG m6b Disrupted -0.059 -0.048 No effect

Mutation Mutation ID Sample Name Cancer Type
chr15:g.47772630A>C COSN8174060 PCSI_0224_Pa_P_526 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2054 tattcATTACAacttgtat
 9
 CUGUAAUA m6b Created -0.154000 -0.119000 -0.010000
hsa-miR-382-5p tattcattACAACTTgtat
 0 GAAGUUGU m7b Created no TS -0.060000 -0.130000

Mutation Mutation ID Sample Name Cancer Type
chr15:g.47772804C>T COSN8745545 AOCS-055-1-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3175 gttcgttTCTCCCCcccca
 0 CGGGGAGA m7b Created no TS -0.123000 0.880000
hsa-miR-4723-5p gttcgtttCTCCCCCccca
 0 UGGGGGAG m7b Created no TS -0.175000 -2.400000
hsa-miR-5698 gttcgtttCTCCCCCccca
 0 UGGGGGAG m7b Created no TS -0.175000 -0.660000
hsa-miR-625-5p gttcgtTTCCCCCccccca
 0 AGGGGGAA m7b Disrupted -0.084000 no TS 3.390000

Mutation Mutation ID Sample Name Cancer Type
chr15:g.47773335G>T COSN8745546 AOCS-061-1-8 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4496 tcaaatgagGTTTCCTggg
 4
 GAGGAAAC m7b (m7b->m6c) 0.043000 0.043000 1.600000

Mutation Mutation ID Sample Name Cancer Type
chr15:g.47773407C>T COSN8174061 PCSI_0083_Pa_P_526 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3157-5p aaccacttaTGGCTGAtga
 0 UUCAGCCA m7b (m6c->m7b) no TS -0.184000 -3.870000
hsa-miR-4691-3p aaccacttaTGGCTGatga
 0 CCAGCCAC m6b Created no TS -0.079000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr15:g.47774030A>G COSN5398010 RK102_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4724-3p tgcaAAGGTAaacgcagat
 0 GUACCUUC m6b Disrupted -0.067000 0.021000 No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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