SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_152754 |
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Gene Symbol: | SEMA3D |
Description: | Homo sapiens sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D (SEMA3D), mRNA. |
Gene Location: | chr7(-):84624871-84751247 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr7:g.84995609T>C | COSN6895609 | RK176_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-586 |
tgttaAATGCATAttttgg |
2 |
UAUGCAUU | m8a | Created | -0.052000 | -0.486000 |
0.100000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr7:g.84996286T>C | COSN15110585 | SM-4B296 | [oesophagus][NS][carcinoma][adenocarcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-494 |
agtATGTTTCgttcctgct |
2 |
UGAAACAU | m7b | (m6c->m7b) | 0.126000 | 0.092000 |
-1.430000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr7:g.84996562T>G | COSN8042939 | 8069446 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-323a-3p |
ctaatTAATGTatgtagag |
2 |
CACAUUAC | m6b | Created | -0.045000 | -0.009000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr7:g.84996567T>C | COSN2239844 | RK051_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr7:g.84996571C>T | COSN15043711 | LP6007594 | [oesophagus][NS][carcinoma][adenocarcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr7:g.84996733C>T | COSN8042940 | 8033523 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3613-3p |
tcatgTTTTTGTatttttc |
0 | ACAAAAAA | m7a | Created | NA | NA |
-0.960000 |
|
hsa-miR-570-3p |
tcaTGTTTTCGtatttttc |
0 | CGAAAACA | m8a | Disrupted | 0.040000 | -0.001000 |
2.160000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr7:g.84996770C>T | 9_16502 | CRC-3-Tumor | Colorectal adenocarcinoma | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4797-5p |
ttgACTCTGTggaggggat |
2 |
GACAGAGU | m7b | (m6c->m7b) | -0.17 | -0.185 |
-0.06 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr7:g.84997082C>A | COSN8042941 | 8069459 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3713 |
ctttGGATACaatactctt |
3 |
GGUAUCCG | m6b | Disrupted | -0.047000 | no TS |
2.390000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr7:g.84997288C>T | COSN8042942 | 8058184 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-711 |
ttgTGGGTCCgacagtaat |
2 |
GGGACCCA | m7b | (m7b->m6c) | -0.093000 | no TS |
3.360000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr7:g.84997318T>A | COSN2239845 | RK023_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-656 |
attttTAATATaaaaaaaa |
0 | AAUAUUAU | m6b | Created | no TS | 0.133000 |
-0.010000 |
|
hsa-miR-656 |
attttTAATATaaaaaaaa |
0 | AAUAUUAU | m6b | Created | no TS | 0.133 |
-0.01 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr7:g.84998711G>C | COSN9772674 | C0094T | [kidney][NS][other][neoplasm] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-1179 |
ggacaGAATGCTTaataaa |
0 | AAGCAUUC | m8a | Disrupted | -0.144000 | no TS |
1.010000 |
|
hsa-miR-4320 |
ggacAGAATCCttaataaa |
3 |
GGGAUUCU | m7b | Created | -0.072000 | -0.192000 |
-0.530000 |
|
hsa-miR-4477b |
ggacagaaTCCTTAATaaa |
2 |
AUUAAGGA | m8a | Created | -0.005000 | -0.140000 |
-0.420000 |
|
hsa-miR-4503 |
ggacagaaTGCTTAAtaaa |
7 |
UUUAAGCA | m7b | Disrupted | -0.112000 | no TS | No effect | |
hsa-miR-541-5p |
ggacagAATCCTTaataaa |
0 | AAAGGAUU | m7b | Created | no TS | -0.158000 |
-2.070000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr7:g.84998721G>A | COSN9512640 | AOCS-104-1-6 | [ovary][NS][other][neoplasm] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3674 |
agcTCTACAAggacagaat |
3 |
AUUGUAGA | m7b | (m6c->m7b) | -0.013000 | -0.041000 |
-0.020000 |
|
hsa-miR-670 |
agctctaCAGGGACagaat |
0 | GUCCCUGA | m7a | Disrupted | NA | NA |
2.320000 |
|
hsa-miR-676-3p |
agctctacaAGGACAGaat |
0 | CUGUCCUA | m7a | (m6a->m7a) | NA | NA |
-0.030000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr7:g.84999002T>A | COSN2239846 | RK001_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4457 |
gctaCCTTGTGgtagggaa |
6 |
UCACAAGG | m7b | Disrupted | -0.229000 | -0.063000 | No effect | |
hsa-miR-4777-3p |
gctacctTGAGGTAgggaa |
0 | AUACCUCA | m7b | Created | no TS | -0.140000 |
-4.110000 |
|
hsa-miR-624-3p |
gctACCTTGTGgtagggaa |
6 |
CACAAGGU | m8a | Disrupted | -0.127000 | no TS | No effect | |
hsa-miR-4457 |
gctaCCTTGTGgtagggaa |
0 | UCACAAGG | m7b | Disrupted | -0.229 | -0.063 | No effect | |
hsa-miR-4777-3p |
gctacctTGAGGTAgggaa |
0 | AUACCUCA | m7b | Created | no TS | -0.14 |
-4.11 |
|
hsa-miR-624-3p |
gctACCTTGTGgtagggaa |
0 | CACAAGGU | m8a | Disrupted | -0.127 | no TS | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr7:g.84999092C>T | COSN4935485 | PD4005a | [breast][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-181a-5p |
ttattccctTGAATGTcca |
6 |
AACAUUCA | m7b | (m6b->m7b) | 0.025000 | -0.020000 |
-1.670000 |
|
hsa-miR-181b-5p |
ttattccctTGAATGTcca |
6 |
AACAUUCA | m7b | (m6b->m7b) | 0.025000 | -0.010000 | No effect | |
hsa-miR-181c-5p |
ttattccctTGAATGTcca |
6 |
AACAUUCA | m7b | (m6b->m7b) | 0.034000 | -0.020000 |
-0.660000 |
|
hsa-miR-181d |
ttattccctTGAATGTcca |
6 |
AACAUUCA | m7b | (m6b->m7b) | 0.015000 | -0.020000 | No effect | |
hsa-miR-4262 |
ttattccctTGAATGTCca |
6 |
GACAUUCA | m8a | (m7a->m8a) | 0.043000 | -0.011000 |
-0.220000 |
|
hsa-miR-4475 |
ttatTCCCTTGaatgtcca |
7 |
CAAGGGAC | m7a | Created | -0.185000 | -0.185000 |
-3.940000 |
|
hsa-miR-561-5p |
ttattcCCTTGAatgtcca |
0 | AUCAAGGA | m6b | Created | no TS | -0.125000 |
-3.660000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr7:g.84999246A>G | COSN2239847 | RK137_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4273 |
tccaAGAACAaatcttgca |
0 | GUGUUCUC | m6b | Disrupted | -0.049000 | 0.028000 |
0.010000 |
|
hsa-miR-4677-5p |
tccAAGAACAAatcttgca |
0 | UUGUUCUU | m8a | Disrupted | -0.231000 | -0.036000 |
0.110000 |
|
hsa-miR-4273 |
tccaAGAACAaatcttgca |
0 | GUGUUCUC | m6b | Disrupted | -0.049 | 0.028 |
0.01 |
|
hsa-miR-4677-5p |
tccAAGAACAAatcttgca |
0 | UUGUUCUU | m8a | Disrupted | -0.231 | -0.036 |
0.11 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr7:g.84999365T>C | COSN2239848 | RK096_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-183-3p |
cccttatagTAATTCAtaa |
2 |
GUGAAUUA | m7b | (m7b->m6b) | -0.106000 | 0.042000 |
2.880000 |
hsa-miR-219-2-3p |
cccttatagCAATTCataa |
0 | AGAAUUGU | m6b | Created | no TS | -0.113000 | No effect |
hsa-miR-2964a-3p |
cccttataGCAATTCataa |
0 | AGAAUUGC | m7b | Created | no TS | -0.412000 |
-0.100000 |
hsa-miR-302f |
cccttatAGCAATTcataa |
0 | UAAUUGCU | m7b | Created | 0.048000 | -0.126000 | No effect |
hsa-miR-625-3p |
ccctTATAGTaattcataa |
0 | GACUAUAG | m6b | Disrupted | -0.177000 | -0.108000 | No effect |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
84995644 | rs191959760 | T | |||||||
C |
hsa-miR-221-3p hsa-miR-222-3p hsa-miR-624-3p |
9 9 12 |
ATGTAGCcttgta ATGTAGCcttgta atgtagCCTTGTA |
Created Created Created |
N N N |
-0.268 -0.268 -0.168 |
|||
84996732 | rs138653004 | G | |||||||
A |
hsa-miR-4517 hsa-miR-570-3p |
1 1 |
gtttTCATATTtt GTTTTCAtatttt |
Created Created |
N N |
-0.025 0.013 |
|||
84996734 | rs76283272 | T | T |
hsa-miR-570-3p |
1 |
aTGTTTTCgtatt |
Disrupted |
N |
0.041 |
C |
hsa-miR-4261 hsa-miR-494-3p |
1 2 |
aTGTTTCCgtatt ATGTTTCcgtatt |
Created Created |
N N |
-0.035 0.083 |
|||
84998054 | rs189339965 | G | G |
hsa-miR-4275 hsa-miR-7849-3p |
1 1 |
GTAATTGtagtat gtAATTGTAgtat |
Disrupted Disrupted |
N N |
-0.009 0.1 |
A |
hsa-miR-625-3p |
1 |
gtaatTATAGTAt |
Created |
N |
0.036 |
|||
84998706 | rs181521389 | A | A |
hsa-miR-4477a hsa-miR-4503 hsa-miR-6792-5p |
7 7 7 |
tgCTTAATAAata TGCTTAAtaaata TGCTTAAtaaata |
Disrupted Disrupted Disrupted |
N N N |
-0.007 -0.112 -0.059 |
84999253 | rs186298749 | C | C |
hsa-miR-3148 hsa-miR-3978 hsa-miR-432-5p hsa-miR-6124 |
7 8 8 7 |
gTTTTCCAagaac gtTTTCCAAgaac gtttTCCAAGAac gTTTTCCAagaac |
Disrupted Disrupted Disrupted Disrupted |
N N N N |
-0.037 -0.046 -0.137 -0.033 |
A |
hsa-miR-510-3p hsa-miR-570-3p hsa-miR-6844 |
8 7 9 |
gtTTTCAAAgaac GTTTTCAaagaac gttttCAAAGAAc |
Created Created Created |
N N N |
0.017 -0.018 -0.068 |