SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_001204255 |
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Gene Symbol: | SCARB2 |
Description: | Homo sapiens scavenger receptor class B, member 2 (SCARB2), transcript variant 2, mRNA. |
Gene Location: | chr4(-):77079891-77135052 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.76159459A>G | ICGC_756D424A-2A78-11E2-96E7-04FD496BB9B8 | CPCG_0102_Pr_P_P1 | ProstateCancer(OICR,CA) | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4284 |
tacaggcGTGAGCCaccgg |
0 | GGGCUCAC | m7b | Created | no TS | -0.147 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.76159879T>C | COSN5063872 | HX25T | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.76160252A>T | COSN7843309 | 8062308 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-145-5p |
ttgtttaaAACTGGAtttc |
3 |
GUCCAGUU | m7b | Disrupted | -0.087000 | no TS |
1.750000 |
|
hsa-miR-4328 |
ttgtttAAAACTGGatttc |
0 | CCAGUUUU | m8a | Disrupted | 0.052000 | no TS |
0.010000 |
|
hsa-miR-488-5p |
ttgtttaaATCTGGatttc |
0 | CCCAGAUA | m6b | Created | no TS | -0.036000 |
-0.490000 |
|
hsa-miR-5195-3p |
ttgtttaaAACTGGATttc |
3 |
AUCCAGUU | m8a | Disrupted | -0.050000 | no TS |
0.890000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.76160540A>G | COSN6843769 | RK190_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-382-3p |
gacaGAATGATggatgttt |
2 |
AAUCAUUC | m7b | Disrupted | 0.093000 | 0.091000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.76161450T>G | COSN7843310 | 8061178 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3065-5p |
tatagtaatTTTGTTGttg |
0 | UCAACAAA | m7b | (m7b->m6b) | -0.129000 | no TS |
3.830000 |
|
hsa-miR-323a-3p |
tataGTAATGTtgttgttg |
0 | CACAUUAC | m7b | Created | no TS | -0.111000 |
-1.210000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr4:g.76161564G>A | COSN523705 | TCGA-BH-A0HP-01 | [breast][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3150a-5p |
ttctggccaGAGGTTaaag |
0 | CAACCUCG | m6b | Disrupted | -0.124000 | no TS |
1.880000 |
hsa-miR-3150b-5p |
ttctggccaGAGGTTaaag |
0 | CAACCUCG | m6b | Disrupted | -0.124000 | no TS |
4.250000 |
hsa-miR-3176 |
ttctGGCCAGaggttaaag |
4 |
ACUGGCCU | m6b | Disrupted | -0.163000 | no TS |
0.060000 |
hsa-miR-3187-3p |
ttcTGGCCAAaggttaaag |
0 | UUGGCCAU | m7a | (m6b->m7a) | no TS | -0.163000 |
-0.480000 |
hsa-miR-3190-5p |
ttcTGGCCAGAggttaaag |
3 |
UCUGGCCA | m8a | Disrupted | -0.512000 | -0.128000 |
-0.070000 |
hsa-miR-4701-5p |
ttcTGGCCAAaggttaaag |
0 | UUGGCCAC | m7a | (m6b->m7a) | no TS | -0.175000 |
-0.010000 |
hsa-miR-588 |
ttcTGGCCAAaggttaaag |
0 | UUGGCCAC | m7a | (m6b->m7a) | no TS | -0.168000 |
-0.080000 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
76161449 | rs151231727 | T | T |
hsa-miR-3065-5p hsa-miR-3529-3p |
2 3 |
gtaatTTTGTTGt gtaattTTGTTGT |
Disrupted Disrupted |
N N |
-0.129 -0.189 |
G |
hsa-miR-4275 |
5 |
GTAATTGtgttgt |
Created |
N |
-0.124 |