SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001036
Gene Symbol: RYR3
Description: Homo sapiens ryanodine receptor 3 (RYR3), transcript variant 1, mRNA.
Gene Location: chr15(+):33603176-34158303
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Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr15:g.33865300G>A COSN9623900 C0066T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-298 tacagTTCTGCaacatatc
 1
 AGCAGAAG m6b Disrupted -0.139000 no TS 12.770000
hsa-miR-3674 tacagtTCTACAAcatatc
 0 AUUGUAGA m7b Created no TS -0.194000 -0.100000
hsa-miR-3678-3p tacagtTCTGCAacatatc
 0 CUGCAGAG m6b Disrupted -0.142000 no TS 5.890000

Mutation Mutation ID Sample Name Cancer Type
chr15:g.33865316G>A COSN8742299 AOCS-084-1-X [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-130a-5p atctgaAATGTGAcatttt
 0 UUCACAUU m7b Disrupted -0.149000 no TS 2.390000
hsa-miR-23a-3p atctgaAATGTGAcatttt
 0 AUCACAUU m7b Disrupted -0.149000 no TS 4.810000
hsa-miR-23b-3p atctgaAATGTGAcatttt
 0 AUCACAUU m7b Disrupted -0.149000 no TS 4.560000
hsa-miR-23c atctgaAATGTGAcatttt
 0 AUCACAUU m7b Disrupted -0.149000 no TS 3.910000

Mutation Mutation ID Sample Name Cancer Type
chr15:g.33865341A>- ICGC_ssm_v3_10591 BN24T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4477b gcctcCCTTAAaaaaaaaa
 1
 AUUAAGGA m6b Disrupted -0.154000 -0.151000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr15:g.33865435G>A COSN5396325 RK140_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3145-3p tgtcaAAATATCgaagaag
 39
 AGAUAUUU m7b Created -0.051000 -0.113000 -0.420000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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