SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_001001890 |
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Gene Symbol: | RUNX1 |
Description: | Homo sapiens runt-related transcription factor 1 (RUNX1), transcript variant 2, mRNA. |
Gene Location: | chr21(-):36160097-36260987 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr21:g.34787974G>A | COSN7145145 | 8067182 | [pancreas][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3689d |
gggtgggcCACCTCCCctc |
0 | GGGAGGUG | m8a | Created | no TS | -0.083000 |
-0.220000 |
hsa-miR-663b |
gggtGGGCCACCtcccctc |
0 | GGUGGCCC | m8a | Created | no TS | -0.206000 |
-1.120000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr21:g.34788396T>G | COSN10026018 | C0007T | [kidney][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3609 |
aagtTCACTTTttttgttc |
0 | CAAAGUGA | m7b | Disrupted | -0.212000 | -0.079000 |
-0.040000 |
hsa-miR-3613-3p |
aagttcactTTTTTTGTtc |
0 | ACAAAAAA | m8a | (m8a->m7a) | 0.566000 | 0.511000 | No effect |
hsa-miR-548ah-5p |
aagtTCACTTTTtttgttc |
0 | AAAAGUGA | m8a | Disrupted | -0.184000 | -0.088000 |
-0.030000 |
hsa-miR-548t-5p |
aagttCACTTTTtttgttc |
0 | CAAAAGUG | m7b | Disrupted | -0.122000 | -0.064000 |
-0.030000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr21:g.34788477T>G | COSN8611711 | 759_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3129-3p |
ctttgtTTAGTTTagactt |
0 | AAACUAAU | m7a | Created | NA | NA | No effect |
hsa-miR-5583-5p |
ctttgtTTAGTTTagactt |
0 | AAACUAAU | m7a | Created | NA | NA |
-0.010000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr21:g.34788527A>T | COSN10026019 | C0035T | [kidney][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr21:g.34788822G>T | COSN9157446 | AOCS-097-1-X | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3613-3p |
tgaaaatTTTTTTGacaat |
0 | ACAAAAAA | m7b | Created | 0.566000 | 0.704000 |
-3.130000 |
hsa-miR-4282 |
tgaAAATTTTtttgacaat |
8 |
UAAAAUUU | m7b | (m6c->m7b) | 0.378000 | 0.488000 |
-0.010000 |
hsa-miR-7-1-3p |
tgaaaATTTGTTtgacaat |
2 |
CAACAAAU | m7b | Disrupted | 0.200000 | 0.171000 | No effect |
hsa-miR-7-2-3p |
tgaaaATTTGTTtgacaat |
2 |
CAACAAAU | m7b | Disrupted | 0.181000 | 0.152000 |
2.100000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr21:g.34788990T>A | COSN5136171 | PD4085a | [breast][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-34a-3p |
tgctCTGATTagaaaggaa |
10 |
CAAUCAGC | m6b | Disrupted | 0.086000 | 0.040000 |
0.010000 |
hsa-miR-361-5p |
tgcTCTGATAAgaaaggaa |
3 |
UUAUCAGA | m8a | Created | -0.021000 | 0.010000 | No effect |
hsa-miR-374a-3p |
tgctCTGATAAGaaaggaa |
4 |
CUUAUCAG | m8a | Created | 0.013000 | 0.019000 | No effect |
hsa-miR-4263 |
tgctctgaTTAGAAaggaa |
10 |
AUUCUAAG | m6b | Disrupted | 0.125000 | no TS |
0.010000 |
hsa-miR-576-5p |
tgctctgATTAGAAaggaa |
10 |
AUUCUAAU | m7b | Disrupted | 0.181000 | no TS |
1.730000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr21:g.34789384T>A | COSN1891500 | RK086_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1278 |
tatttCAGTACTttctttt |
15 |
UAGUACUG | m7b | Created | -0.065000 | -0.187000 |
-0.270000 |
hsa-miR-3133 |
tatttcaGTTCTTTctttt |
0 | UAAAGAAC | m7b | Disrupted | 0.083000 | 0.038000 |
0.050000 |
hsa-miR-4511 |
tatttcAGTTCTTtctttt |
0 | GAAGAACU | m7b | Disrupted | 0.296000 | 0.250000 | No effect |
hsa-miR-548av-5p |
tatttcaGTACTTTctttt |
0 | AAAAGUAC | m7b | Created | no TS | 0.034000 |
-0.020000 |
hsa-miR-548k |
tatttcaGTACTTTctttt |
0 | AAAAGUAC | m7b | Created | no TS | 0.034000 |
-0.010000 |
hsa-miR-1278 |
tatttCAGTACTttctttt |
0 | UAGUACUG | m7b | Created | -0.065 | -0.187 |
-0.27 |
hsa-miR-3133 |
tatttcaGTTCTTTctttt |
0 | UAAAGAAC | m7b | Disrupted | 0.083 | 0.038 |
0.05 |
hsa-miR-4511 |
tatttcAGTTCTTtctttt |
0 | GAAGAACU | m7b | Disrupted | 0.296 | 0.25 | No effect |
hsa-miR-548av-5p |
tatttcaGTACTTTctttt |
0 | AAAAGUAC | m7b | Created | no TS | 0.034 |
-0.02 |
hsa-miR-548k |
tatttcaGTACTTTctttt |
0 | AAAAGUAC | m7b | Created | no TS | 0.034 |
-0.01 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr21:g.34789387A>C | COSN1891501 | RK086_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-191-5p |
acatatTTCCGTTctttct |
0 | CAACGGAA | m7b | Created | no TS | -0.094000 | No effect |
hsa-miR-4511 |
acatatttcAGTTCTTtct |
0 | GAAGAACU | m7b | (m7b->m6b) | 0.296000 | 0.250000 | No effect |
hsa-miR-191-5p |
acatatTTCCGTTctttct |
0 | CAACGGAA | m7b | Created | no TS | -0.094 | No effect |
hsa-miR-4511 |
acatatttcAGTTCTTtct |
0 | GAAGAACU | m7b | (m7b->m6b) | 0.296 | 0.25 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr21:g.34789821T>G | COSN1891502 | RK133_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3188 |
aaaccAGCCTCatgctctg |
3 |
AGAGGCUU | m6b | Disrupted | -0.028000 | no TS |
0.300000 |
hsa-miR-3929 |
aaacCAGCCTCatgctctg |
12 |
GAGGCUGA | m7a | Disrupted | -0.010000 | -0.010000 |
0.160000 |
hsa-miR-4419b |
aaacCAGCCTCatgctctg |
12 |
GAGGCUGA | m7a | Disrupted | -0.029000 | -0.029000 |
0.150000 |
hsa-miR-4478 |
aaacCAGCCTCatgctctg |
12 |
GAGGCUGA | m7a | Disrupted | 0.018000 | 0.018000 |
0.130000 |
hsa-miR-485-5p |
aaacCAGCCTCatgctctg |
0 | AGAGGCUG | m7b | Disrupted | -0.110000 | -0.043000 |
2.910000 |
hsa-miR-3188 |
aaaccAGCCTCatgctctg |
0 | AGAGGCUU | m6b | Disrupted | -0.028 | no TS |
0.3 |
hsa-miR-3929 |
aaacCAGCCTCatgctctg |
0 | GAGGCUGA | m7a | Disrupted | -0.01 | -0.01 |
0.16 |
hsa-miR-4419b |
aaacCAGCCTCatgctctg |
0 | GAGGCUGA | m7a | Disrupted | -0.029 | -0.029 |
0.15 |
hsa-miR-4478 |
aaacCAGCCTCatgctctg |
0 | GAGGCUGA | m7a | Disrupted | 0.018 | 0.018 |
0.13 |
hsa-miR-485-5p |
aaacCAGCCTCatgctctg |
0 | AGAGGCUG | m7b | Disrupted | -0.11 | -0.043 |
2.91 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr21:g.34790435T>G | COSN9157447 | AOCS-116-1-3 | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1226-3p |
tccaaatgaGCTGGTGgtt |
1 |
UCACCAGC | m7b | (m6b->m7b) | -0.279000 | -0.363000 | No effect |
hsa-miR-4267 |
tccaaatGAGCTGGtggtt |
0 | UCCAGCUC | m7b | Created | -0.115000 | -0.217000 |
-4.190000 |
hsa-miR-5694 |
tccaaATGATCTGgtggtt |
12 |
CAGAUCAU | m8a | Disrupted | 0.063000 | no TS | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr21:g.34790525T>C | COSN5452751 | RK307_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-224-3p |
ttatggcACCATTTTtatt |
0 | AAAAUGGU | m8a | Created | no TS | 0.093000 |
-1.590000 |
hsa-miR-33b-3p |
ttatGGCACTatttttatt |
0 | CAGUGCCU | m6b | Disrupted | -0.233000 | -0.147000 |
4.500000 |
hsa-miR-371a-3p |
ttatGGCACTatttttatt |
14 |
AAGUGCCG | m6b | Disrupted | -0.127000 | no TS |
2.510000 |
hsa-miR-371b-3p |
ttatGGCACTatttttatt |
14 |
AAGUGCCC | m6b | Disrupted | -0.093000 | no TS |
0.610000 |
hsa-miR-515-3p |
ttatGGCACTatttttatt |
0 | GAGUGCCU | m6b | Disrupted | -0.217000 | -0.128000 |
6.280000 |
hsa-miR-519e-3p |
ttatGGCACTatttttatt |
0 | AAGUGCCU | m6b | Disrupted | -0.215000 | -0.119000 |
2.530000 |
hsa-miR-522-3p |
ttatggcACCATTTTtatt |
0 | AAAAUGGU | m8a | Created | no TS | 0.083000 |
-0.550000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr21:g.34791522A>T | cosmic_v64_1760549 | Leukemia/T-ALL | ||||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3124-3p |
catGGAAAGTaatatgatt |
0 | ACUUUCCU | m7a | (m6b->m7a) | 0.152 | 0.197 |
-0.01 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr21:g.34791822G>A | COSN5769094 | HX33T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1470 |
aagattccCGGAGGGaaac |
0 | GCCCUCCG | m7b | Disrupted | -0.519000 | -0.140000 |
5.490000 |
hsa-miR-204-3p |
aagaTTCCCAGagggaaac |
4 |
GCUGGGAA | m7b | Created | -0.122000 | -0.346000 |
-0.060000 |
hsa-miR-326 |
aagattCCCAGAGGgaaac |
0 | CCUCUGGG | m8a | Created | no TS | -0.258000 |
-0.670000 |
hsa-miR-330-5p |
aagattCCCAGAGggaaac |
0 | UCUCUGGG | m7b | Created | no TS | -0.202000 |
-0.050000 |
hsa-miR-4314 |
aagatTCCCAGAGggaaac |
3 |
CUCUGGGA | m8a | Created | -0.398000 | -0.548000 |
-0.050000 |
hsa-miR-4497 |
aagatTCCCGGAGggaaac |
4 |
CUCCGGGA | m8a | Disrupted | -0.287000 | no TS |
1.110000 |
hsa-miR-4646-5p |
aagaTTCCCAGagggaaac |
4 |
ACUGGGAA | m7b | Created | -0.129000 | -0.406000 |
-0.400000 |
hsa-miR-4667-3p |
aagattcccGGAGGGAaac |
0 | UCCCUCCU | m7a | (m7a->m6a) | -0.468000 | -0.308000 |
0.900000 |
hsa-miR-642a-5p |
aagattcccAGAGGGAaac |
0 | GUCCCUCU | m7b | (m6b->m7b) | -0.127000 | -0.297000 |
0.270000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr21:g.34791884C>T | COSN15001571 | LP6007414-DNA_A02 | [oesophagus][NS][carcinoma][adenocarcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-18a-5p |
gacGCACCTTgagggtgtc |
17 |
UAAGGUGC | m7b | (m6c->m7b) | -0.305000 | -0.355000 | No effect |
hsa-miR-18b-5p |
gacGCACCTTgagggtgtc |
17 |
UAAGGUGC | m7b | (m6c->m7b) | -0.295000 | -0.345000 | No effect |
hsa-miR-4735-3p |
gacGCACCTTgagggtgtc |
17 |
AAAGGUGC | m7b | (m6c->m7b) | -0.389000 | -0.457000 | No effect |
hsa-miR-4761-5p |
gacgCACCTTGagggtgtc |
0 | ACAAGGUG | m7b | Created | no TS | -0.179000 |
-0.070000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr21:g.34792014G>C | cosmic_v64_1860009 | Esophageal | ||||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1307-3p |
ccgtcctggCGCCGAGggc |
0 | ACUCGGCG | m7b | (m6b->m7b) | no TS | -0.15 |
-0.97 |
hsa-miR-1469 |
ccgtcctgGCGCCGAGggc |
0 | CUCGGCGC | m8a | Created | no TS | -0.269 |
-1.14 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr21:g.34792097C>T | COSN5769095 | HCC159 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3714 |
gcgggccgCTGCCTTCgcc |
2 |
GAAGGCAG | m8a | Created | -0.074000 | -0.053000 | No effect |
hsa-miR-3960 |
gcgggCCGCCGCCttcgcc |
0 | GGCGGCGG | m8a | Disrupted | -0.524000 | -0.244000 | No effect |
hsa-miR-4467 |
gcgggcCGCCGCCttcgcc |
0 | UGGCGGCG | m7b | Disrupted | -0.698000 | -0.479000 | No effect |
hsa-miR-885-3p |
gcgggcCGCTGCCTtcgcc |
0 | AGGCAGCG | m8a | Created | no TS | -0.110000 | No effect |
hsa-miR-3714 |
gcgggccgCTGCCTTCgcc |
2 |
GAAGGCAG | m8a | Created | -0.074000 | -0.053000 | No effect |
hsa-miR-3960 |
gcgggCCGCCGCCttcgcc |
0 | GGCGGCGG | m8a | Disrupted | -0.524000 | -0.244000 | No effect |
hsa-miR-4467 |
gcgggcCGCCGCCttcgcc |
0 | UGGCGGCG | m7b | Disrupted | -0.698000 | -0.479000 | No effect |
hsa-miR-885-3p |
gcgggcCGCTGCCTtcgcc |
0 | AGGCAGCG | m8a | Created | no TS | -0.110000 | No effect |