SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_021133
Gene Symbol: RNASEL
Description: Homo sapiens ribonuclease L (2,5-oligoisoadenylate synthetase-dependent) (RNASEL), mRNA.
Gene Location: chr1(-):182542768-182558394
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr1:g.182575040A>G 10_17375 6408 Breast cancer
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-105-5p tcccCATTTGAgaactgag
 0 UCAAAUGC m7a Created -0.019 -0.003 No effect
hsa-miR-2116-5p tccccattTAAGAACtgag
 0 GGUUCUUA m7b Disrupted -0.104 no TS No effect
hsa-miR-302a-5p tccccaTTTAAGaactgag
 0 ACUUAAAC m6b Disrupted 0.045 no TS 0.6
hsa-miR-371a-5p tccccaTTTGAGaactgag
 0 ACUCAAAC m6b Created no TS 0.006 -0.06
hsa-miR-371b-5p tccccaTTTGAGaactgag
 0 ACUCAAAA m6b Created no TS 0.027 -0.196
hsa-miR-373-5p tccccaTTTGAGaactgag
 0 ACUCAAAA m6b Created no TS 0.017 -3.56
hsa-miR-4694-3p tccCCATTTGagaactgag
 10
 CAAAUGGA m7a (m6b->m7a) -0.033 no TS 0.62
hsa-miR-513c-5p tccccatTTGAGAActgag
 0 UUCUCAAG m7a Created 0.025 0.003 -0.18
hsa-miR-514b-5p tccccatTTGAGAActgag
 0 UUCUCAAG m7a Created 0.015 -0.01 -4.71
hsa-miR-616-5p tccccaTTTGAGaactgag
 0 ACUCAAAA m6b Created no TS 0.031 -0.14

Mutation Mutation ID Sample Name Cancer Type
chr1:g.182575103G>A COSN5359112 RK057_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1277-5p gctgcATATATTacaattc
 0 AAAUAUAU m7b Created no TS 0.051000 -0.050000
hsa-miR-194-5p gctgcataTGTTACAattc
 0 UGUAACAG m7a Disrupted -0.077000 no TS 5.250000
hsa-miR-2054 gctgcataTATTACAattc
 0 CUGUAAUA m7b Created no TS -0.180000 -1.130000
hsa-miR-5580-3p gctgCATATGTtacaattc
 2
 CACAUAUG m7b Disrupted -0.164000 -0.093000 0.250000

Mutation Mutation ID Sample Name Cancer Type
chr1:g.182575136A>G COSN1416494 RK086_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3121-5p tgcacCAAAGGAatgagtg
 0 UCCUUUGC m7a Created no TS -0.083000 No effect
hsa-miR-9-5p tgcACCAAAGgaatgagtg
 0 UCUUUGGU m7b (m6c->m7b) no TS -0.073000 -2.260000
hsa-miR-3121-5p tgcacCAAAGGAatgagtg
 0 UCCUUUGC m7a Created no TS -0.083 No effect
hsa-miR-9-5p tgcACCAAAGgaatgagtg
 0 UCUUUGGU m7b (m6c->m7b) no TS -0.073 -2.26

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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