SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
  Home Search Help Download  

PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_033103
Gene Symbol: RHPN2
Description: Homo sapiens rhophilin, Rho GTPase binding protein 2 (RHPN2), mRNA.
Gene Location: chr19(-):33469497-33555824
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr19:g.32978870C>A COSN9355056 AOCS-055-1-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3199 caccacaaCAGTCCCacta
 0 AGGGACUG m7b Created no TS -0.430000 -8.800000
hsa-miR-365a-5p caccacaacAGTCCCacta
 0 AGGGACUU m6b Created no TS -0.179000 -5.130000
hsa-miR-365b-5p caccacaacAGTCCCacta
 0 AGGGACUU m6b Created no TS -0.179000 -1.270000
hsa-miR-92b-5p caccacaaCCGTCCCacta
 1
 AGGGACGG m7b Disrupted -0.609000 no TS 0.490000

Mutation Mutation ID Sample Name Cancer Type
chr19:g.32978914C>T COSN9355057 AOCS-055-1-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3929 cacccaccTCAGCCTCcca
 1
 GAGGCUGA m8a Disrupted -0.135000 -0.067000 0.010000
hsa-miR-3975 cacccacctTAGCCTCcca
 0 UGAGGCUA m7b (m6b->m7b) no TS -0.136000 -1.360000
hsa-miR-4419b cacccaccTCAGCCTCcca
 1
 GAGGCUGA m8a Disrupted -0.154000 -0.076000 0.020000
hsa-miR-4478 cacccaccTCAGCCTCcca
 1
 GAGGCUGA m8a Disrupted -0.191000 -0.104000 No effect
hsa-miR-4735-3p caccCACCTTagcctccca
 0 AAAGGUGC m6b Created no TS -0.072000 -0.060000
hsa-miR-485-5p cacccacctCAGCCTCcca
 1
 AGAGGCUG m7b (m7b->m6b) -0.273000 -0.125000 -0.070000

Mutation Mutation ID Sample Name Cancer Type
chr19:g.32978923C>T COSN9355058 AOCS-055-1-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-197-5p caaatgaTCTACCCacctc
 0 CGGGUAGA m7b Created no TS -0.353000 -0.030000
hsa-miR-3132 caaatgaTCTACCCAcctc
 0 UGGGUAGA m8a Created no TS -0.374000 -0.260000
hsa-miR-3165 caaatgATCCACCcacctc
 1
 AGGUGGAU m7b Disrupted -0.143000 no TS 3.210000
hsa-miR-363-5p caaatgaTCCACCCacctc
 1
 CGGGUGGA m7b Disrupted -0.359000 no TS 3.530000
hsa-miR-4483 caaatgatCCACCCacctc
 1
 GGGGUGGU m6b Disrupted -0.151000 no TS 3.480000
hsa-miR-5694 caaATGATCTacccacctc
 0 CAGAUCAU m7b (m6c->m7b) no TS -0.192000 -8.130000

Mutation Mutation ID Sample Name Cancer Type
chr19:g.32978924C>T COSN9355059 AOCS-055-1-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1262 tcaaatgatTCACCCAcct
 0 AUGGGUGA m7b (m6b->m7b) no TS -0.185000 -4.060000
hsa-miR-15b-3p tcaaATGATTCacccacct
 5
 CGAAUCAU m7b Created -0.181000 -0.320000 -2.860000
hsa-miR-3165 tcaaatgATCCACCcacct
 1
 AGGUGGAU m7b Disrupted -0.143000 no TS 2.240000
hsa-miR-363-5p tcaaatgaTCCACCCacct
 1
 CGGGUGGA m7b Disrupted -0.359000 no TS 2.870000
hsa-miR-4483 tcaaatgatCCACCCacct
 1
 GGGGUGGU m6b Disrupted -0.151000 no TS 3.480000
hsa-miR-4701-3p tcaaatgatTCACCCAcct
 0 AUGGGUGA m7b (m6b->m7b) no TS -0.175000 -2.110000

Mutation Mutation ID Sample Name Cancer Type
chr19:g.32979088C>T COSN9355060 AOCS-055-1-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-377-5p agctcagtgCAACCTCcgc
 1
 AGAGGUUG m7b (m7b->m6b) -0.019000 no TS 0.220000

Mutation Mutation ID Sample Name Cancer Type
chr19:g.32979445C>G COSN9355061 AOCS-055-1-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1283 atgctaTTTGTAGAaaaag
 1
 UCUACAAA m8a Created -0.099000 -0.278000 -0.990000
hsa-miR-4777-5p atgctattTCTAGAAaaag
 1
 UUCUAGAU m7a Disrupted -0.078000 no TS 1.660000
hsa-miR-518d-5p atgctattTCTAGAaaaag
 1
 CUCUAGAG m6b Disrupted -0.086000 no TS 0.030000
hsa-miR-518e-5p atgctattTCTAGAaaaag
 1
 CUCUAGAG m6b Disrupted -0.079000 no TS 0.010000
hsa-miR-518f-5p atgctattTCTAGAaaaag
 1
 CUCUAGAG m6b Disrupted -0.086000 no TS 0.050000
hsa-miR-519a-5p atgctattTCTAGAaaaag
 1
 CUCUAGAG m6b Disrupted -0.079000 no TS 0.010000
hsa-miR-519b-5p atgctattTCTAGAaaaag
 1
 CUCUAGAG m6b Disrupted -0.079000 no TS 0.010000
hsa-miR-519c-5p atgctattTCTAGAaaaag
 1
 CUCUAGAG m6b Disrupted -0.079000 no TS 0.010000
hsa-miR-520c-5p atgctattTCTAGAaaaag
 1
 CUCUAGAG m6b Disrupted -0.086000 no TS 0.030000
hsa-miR-520d-5p atgctaTTTGTAGaaaaag
 0 CUACAAAG m7a Created NA NA No effect
hsa-miR-522-5p atgctattTCTAGAaaaag
 1
 CUCUAGAG m6b Disrupted -0.079000 no TS 0.010000
hsa-miR-523-5p atgctattTCTAGAaaaag
 1
 CUCUAGAG m6b Disrupted -0.079000 no TS 0.010000
hsa-miR-524-5p atgctaTTTGTAGaaaaag
 0 CUACAAAG m7a Created NA NA -0.020000
hsa-miR-526a atgctattTCTAGAaaaag
 1
 CUCUAGAG m6b Disrupted -0.086000 no TS 0.030000
hsa-miR-5680 atgctATTTCTagaaaaag
 0 GAGAAAUG m6b Disrupted 0.050000 no TS 0.020000

Mutation Mutation ID Sample Name Cancer Type
chr19:g.32979499C>T COSN9355062 AOCS-055-1-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-10a-3p atagGAATTTattaaccta
 0 CAAAUUCG m6b Created no TS -0.033000 -4.830000
hsa-miR-4452 atagGAATTCAttaaccta
 0 UUGAAUUC m7b Disrupted -0.202000 -0.117000 0.010000
hsa-miR-569 ataggaattCATTAACcta
 0 AGUUAAUG m7b (m7b->m6b) -0.137000 no TS 0.320000

Mutation Mutation ID Sample Name Cancer Type
chr19:g.32979573C>G COSN9355063 AOCS-055-1-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1229 aaggcaGGTGAGAGgactg
 0 CUCUCACC m8a Created no TS -0.182000 -0.050000
hsa-miR-146a-3p aaggcaggTCAGAGGactg
 0 CCUCUGAA m7a Disrupted NA NA 0.290000
hsa-miR-192-5p aaggcAGGTCAGaggactg
 0 CUGACCUA m7a Disrupted NA NA 1.840000
hsa-miR-301a-5p aaggcagGTCAGAGgactg
 3
 GCUCUGAC m7b Disrupted -0.123000 no TS 3.890000
hsa-miR-3183 aaggcaggtGAGAGGactg
 0 GCCUCUCU m6b Created no TS -0.090000 -3.090000
hsa-miR-4256 aaggcaGGTCAGAggactg
 3
 AUCUGACC m7b Disrupted -0.171000 no TS 4.560000
hsa-miR-4723-3p aaggcaggtGAGAGGactg
 0 CCCUCUCU m6b Created no TS -0.104000 -3.490000
hsa-miR-631 aaggCAGGTCagaggactg
 7
 AGACCUGG m6b Disrupted -0.131000 no TS 0.040000


Mutation Mutation ID Sample Name Cancer Type
chr19:g.32979683C>G COSN9355064 AOCS-055-1-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr19:g.32979855T>G COSN14799637 8051709 [pancreas][NS][carcinoid-endocrine_tumour][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-548ac ttgatgtGTTTTTatgaag
 2
 CAAAAACC m6b Disrupted 0.028000 no TS -0.360000
hsa-miR-548ae ttgatgtGTTTTTatgaag
 2
 CAAAAACU m6b Disrupted 0.037000 no TS -0.270000
hsa-miR-548ah-3p ttgatgtGTTTTTatgaag
 2
 CAAAAACU m6b Disrupted 0.041000 no TS -0.270000
hsa-miR-548am-3p ttgatgtGTTTTTatgaag
 2
 CAAAAACU m6b Disrupted 0.041000 no TS -0.220000
hsa-miR-548aq-3p ttgatgtGTTTTTatgaag
 2
 CAAAAACU m6b Disrupted 0.037000 no TS -0.257000
hsa-miR-548d-3p ttgatgtGTTTTTatgaag
 2
 CAAAAACC m6b Disrupted 0.034000 no TS -0.216000
hsa-miR-548h-3p ttgatgtGTTTTTatgaag
 2
 CAAAAACC m6b Disrupted 0.034000 no TS 0.200000
hsa-miR-548z ttgatgtGTTTTTatgaag
 2
 CAAAAACC m6b Disrupted 0.034000 no TS 0.200000

Mutation Mutation ID Sample Name Cancer Type
chr19:g.32979953C>G COSN9355065 AOCS-055-1-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-197-3p tttccgGTGGTGActcggc
 0 UUCACCAC m7b Created no TS -0.127000 -0.980000
hsa-miR-3065-3p tttccGGTGCTGActcggc
 3
 UCAGCACC m8a Disrupted -0.392000 no TS 0.320000
hsa-miR-5702 tttccggtgCTGACTCggc
 0 UGAGUCAG m7b (m7b->m6b) -0.133000 no TS 6.300000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
32979958 rs193271085 C C hsa-miR-5093
1
 CATTTCCggtgct
 Disrupted
N
 -0.114
T hsa-miR-29a-3p
hsa-miR-29b-3p
hsa-miR-29c-3p
hsa-miR-5680
2
2
2
1
 catttcTGGTGCT
catttcTGGTGCT
catttcTGGTGCT
CATTTCTggtgct
 Created
Created
Created
Created
N
N
N
N
 -0.24
-0.24
-0.24
-0.034

Genome Browser