SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_018715 |
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Gene Symbol: | RCC2 |
Description: | Homo sapiens regulator of chromosome condensation 2 (RCC2), transcript variant 2, mRNA. |
Gene Location: | chr1(-):17733250-17766220 |
Browse Associations |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr1:g.17407068A>C | COSN6430621 | CHC322T | [liver][NS][carcinoma][hepatocellular_carcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-1305 |
agaTTGAAAAatgggcttc |
1 |
UUUUCAAC | m7a | (m7a->m6b) | 0.036000 | no TS |
0.230000 |
|
hsa-miR-4641 |
agattgaaaCATGGGCttc |
0 | UGCCCAUG | m7b | (m6b->m7b) | no TS | -0.283000 |
-1.810000 |
|
hsa-miR-4716-5p |
agattgaAACATGGgcttc |
1 |
UCCAUGUU | m7b | Created | -0.067000 | -0.182000 |
-0.070000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr1:g.17408329A>G | COSN6009877 | RK175_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4719 |
aacATTTGTGtcagttgag |
0 | UCACAAAU | m7b | (m6c->m7b) | no TS | 0.098000 |
-4.220000 |
hsa-miR-642a-3p |
aacattTGTGTCagttgag |
0 | AGACACAU | m6b | Created | no TS | -0.023000 | No effect |
hsa-miR-642b-3p |
aacattTGTGTCagttgag |
0 | AGACACAU | m6b | Created | no TS | -0.027000 |
-0.010000 |
hsa-miR-888-3p |
aacatttgTGTCAGTtgag |
0 | GACUGACA | m7b | Created | no TS | -0.046000 |
-0.010000 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
17407068 | rs7191 | A | A |
hsa-miR-1305 hsa-miR-153-5p hsa-miR-335-3p |
1 2 1 |
TTGAAAAatgggc ttgAAAAATGggc tTGAAAAAtgggc |
Disrupted Disrupted Disrupted |
N N N |
0.036 0.091 0.051 |
C |
hsa-miR-4641 hsa-miR-4716-5p |
11 2 |
ttgaaaCATGGGC ttgaAACATGGgc |
Created Created |
N N |
-0.283 -0.115 |