| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_007023 |
|---|---|
| Gene Symbol: | RAPGEF4 |
| Description: | Homo sapiens Rap guanine nucleotide exchange factor (GEF) 4 (RAPGEF4), transcript variant 2, mRNA. |
| Gene Location: | chr2(+):173600524-173917620 |
| Browse Associations | |
| Browse Pathways | |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr2:g.173052368A>G | COSN1806962 | RK035_C01 | [liver][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-1185-1-3p |
tgaaTGTATATagaataat |
0 | AUAUACAG | m7a | Disrupted | NA | NA |
0.320000 |
| hsa-miR-1185-2-3p |
tgaaTGTATATagaataat |
0 | AUAUACAG | m7a | Disrupted | NA | NA |
3.520000 |
| hsa-miR-1185-1-3p |
tgaaTGTATATagaataat |
0 | AUAUACAG | m7a | Disrupted | NA | NA |
0.32 |
| hsa-miR-1185-2-3p |
tgaaTGTATATagaataat |
0 | AUAUACAG | m7a | Disrupted | NA | NA |
3.52 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr2:g.173052766G>A | COSN4799236 | tumor_4177376 | [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-3924 |
atttagTACATAattttga |
7 |
AUAUGUAU | m6b | Created | -0.227000 | -0.324000 | No effect |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr2:g.173052790T>C | COSN9116699 | AOCS-139-12-5 | [ovary][NS][other][neoplasm] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-4668-5p |
attTTTTCCCgttttcaca |
0 | AGGGAAAA | m7b | (m6b->m7b) | no TS | -0.181000 |
-3.510000 |
| hsa-miR-4681 |
attttTTCCCGTTttcaca |
0 | AACGGGAA | m8a | Created | no TS | -0.386000 |
-3.270000 |
| hsa-miR-548ad |
attttttccCGTTTTCaca |
0 | GAAAACGA | m7a | (m6b->m7a) | NA | NA |
-5.030000 |
| hsa-miR-570-3p |
attttttccTGTTTTCaca |
6 |
CGAAAACA | m7b | (m7b->m6c) | -0.151000 | -0.024000 |
1.630000 |