SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_002886 |
---|---|
Gene Symbol: | RAP2B |
Description: | Homo sapiens RAP2B, member of RAS oncogene family (RAP2B), mRNA. |
Gene Location: | chr3(+):152880028-152886263 |
Browse Associations |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr3:g.153163374G>A | COSN1270039 | HCC82T | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3194-5p |
gggagcccGGCTGGCCtcc |
3 |
GGCCAGCC | m8a | Disrupted | -0.124000 | no TS | No effect | |
hsa-miR-3944-3p |
gggAGCCCGActggcctcc |
0 | UUCGGGCU | m7b | (m6b->m7b) | no TS | -0.190000 |
1.190000 |
|
hsa-miR-3194-5p |
gggagcccGGCTGGCCtcc |
3 |
GGCCAGCC | m8a | Disrupted | -0.124000 | no TS | No effect | |
hsa-miR-3944-3p |
gggAGCCCGActggcctcc |
0 | UUCGGGCU | m7b | (m6b->m7b) | no TS | -0.190000 |
1.190000 |
|
hsa-miR-3194-5p |
gggagcccGGCTGGCCtcc |
0 | GGCCAGCC | m8a | Disrupted | -0.124 | no TS | No effect | |
hsa-miR-3944-3p |
gggAGCCCGActggcctcc |
0 | UUCGGGCU | m7b | (m6b->m7b) | no TS | -0.19 |
1.19 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr3:g.153165014G>T | COSN7623796 | PCSI_0002_Pa_P | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3162-3p |
ttgtaGGTAGGGAacaaga |
0 | UCCCUACC | m8a | Disrupted | -0.320000 | -0.136000 |
0.010000 |
|
hsa-miR-587 |
ttgtaggTATGGAAcaaga |
0 | UUUCCAUA | m7b | Created | no TS | 0.071000 |
-1.580000 |
|
hsa-miR-642b-5p |
ttgtaggtAGGGAACaaga |
1 |
GGUUCCCU | m7b | Disrupted | -0.174000 | -0.080000 |
1.790000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr3:g.153165188A>T | COSN1270040 | HX14T | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-331-5p |
gttATACCTAGtgatgttt |
0 | CUAGGUAU | m8a | Disrupted | -0.027000 | no TS |
3.910000 |
|
hsa-miR-34c-3p |
gttataccTAGTGATgttt |
2 |
AAUCACUA | m7b | Disrupted | 0.046000 | no TS |
0.150000 |
|
hsa-miR-4457 |
gttataCCTTGTGAtgttt |
1 |
UCACAAGG | m8a | Created | 0.020000 | -0.078000 |
-4.230000 |
|
hsa-miR-513b |
gttatacCTTGTGAtgttt |
2 |
UUCACAAG | m7b | Created | 0.059000 | 0.075000 |
-0.640000 |
|
hsa-miR-624-3p |
gttatACCTTGTGatgttt |
0 | CACAAGGU | m8a | Created | no TS | -0.037000 |
-2.150000 |
|
hsa-miR-331-5p |
gttATACCTAGtgatgttt |
0 | CUAGGUAU | m8a | Disrupted | -0.027 | no TS |
3.91 |
|
hsa-miR-34c-3p |
gttataccTAGTGATgttt |
0 | AAUCACUA | m7b | Disrupted | 0.046 | no TS |
0.15 |
|
hsa-miR-4457 |
gttataCCTTGTGAtgttt |
0 | UCACAAGG | m8a | Created | 0.02 | -0.078 |
-4.23 |
|
hsa-miR-513b |
gttatacCTTGTGAtgttt |
0 | UUCACAAG | m7b | Created | 0.059 | 0.075 |
-0.64 |
|
hsa-miR-624-3p |
gttatACCTTGTGatgttt |
0 | CACAAGGU | m8a | Created | no TS | -0.037 |
-2.15 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr3:g.153165919C>T | COSN6736843 | RK220_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-105-5p |
aagaaaagGCATTTGgcat |
11 |
UCAAAUGC | m7b | Disrupted | 0.362000 | 0.296000 |
0.010000 |
|
hsa-miR-532-5p |
aagaaAAGGCATttggcat |
6 |
CAUGCCUU | m7b | Disrupted | -0.050000 | no TS |
0.060000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr3:g.153167276A>T | COSN7623797 | PCSI_0112_Pa_P | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-577 |
tcTTTATCTAttaactgga |
3 |
UAGAUAAA | m8a | (m8a->m7a) | 0.544000 | 0.494000 |
0.010000 |
|
hsa-miR-633 |
tctttatCTATTAactgga |
2 |
CUAAUAGU | m6b | Disrupted | 0.475000 | 0.398000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr3:g.153167528A>G | COSN7623798 | PCSI_0083_Pa_P_526 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr3:g.153167607A>C | COSN8488506 | 3844_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-1183 |
gtctaCTACAGTtagagaa |
1 |
CACUGUAG | m7b | Disrupted | -0.078000 | 0.017000 | No effect | |
hsa-miR-20b-3p |
gtctACTACAGTtagagaa |
1 |
ACUGUAGU | m8a | Disrupted | -0.151000 | no TS |
1.540000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr3:g.153168405T>C | COSN9136939 | AOCS-148-1-4 | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-106a-5p |
ccattttCACTTTTaatgc |
0 | AAAAGUGC | m7a | Created | 0.067000 | 0.067000 |
-0.020000 |
hsa-miR-3609 |
ccatttTCACTTTtaatgc |
0 | CAAAGUGA | m7b | Created | -0.001000 | -0.177000 |
-2.170000 |
hsa-miR-3646 |
ccattTTCATTTTtaatgc |
3 |
AAAAUGAA | m8a | Disrupted | 0.439000 | 0.535000 |
0.080000 |
hsa-miR-3662 |
ccatttTCATTTTtaatgc |
3 |
GAAAAUGA | m7b | Disrupted | 0.378000 | 0.468000 | No effect |
hsa-miR-548ah-5p |
ccatttTCACTTTTaatgc |
0 | AAAAGUGA | m8a | Created | 0.002000 | -0.174000 |
-0.010000 |
hsa-miR-548c-3p |
ccattttcATTTTTaatgc |
3 |
CAAAAAUC | m6b | Disrupted | 1.021000 | 0.949000 | No effect |
hsa-miR-548n |
ccattttcACTTTTaatgc |
9 |
CAAAAGUA | m6b | Created | 0.433000 | 0.405000 |
-0.350000 |
hsa-miR-548t-5p |
ccattttCACTTTTaatgc |
9 |
CAAAAGUG | m7b | Created | 0.477000 | 0.235000 |
-2.740000 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
153163749 | rs13093372 | A | A |
hsa-miR-205-5p hsa-miR-218-2-3p hsa-miR-5007-3p hsa-miR-584-5p hsa-miR-758-5p |
10 3 6 3 3 |
aaccatATGAAGG AACCATAtgaagg aacCATATGAAgg AACCATAtgaagg AACCATAtgaagg |
Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N |
-0.132 -0.097 -0.051 -0.064 -0.044 |
T |
hsa-miR-105-5p hsa-miR-224-3p hsa-miR-3671 hsa-miR-522-3p hsa-miR-607 hsa-miR-7853-5p |
6 3 6 3 6 6 |
aacCATTTGAagg aACCATTTgaagg aaccATTTGAAgg aACCATTTgaagg aaccATTTGAAgg aacCATTTGAagg |
Created Created Created Created Created Created |
N N N N N N |
0.017 -0.026 0.079 -0.026 0.107 0.014 |
|||
153164233 | rs140629909 | G | G |
hsa-miR-1183 hsa-miR-4742-3p |
8 6 |
aaTACAGTAcaaa AATACAGtacaaa |
Disrupted Disrupted |
N N |
-0.026 -0.075 |
T |
hsa-miR-2054 |
9 |
aatacATTACAAa |
Created |
N |
0.006 |
|||
153166486 | rs185548519 | T | T |
hsa-miR-577 |
6 |
tcTTTATCTtggg |
Disrupted |
N |
0.206 |
C |
hsa-miR-548ag hsa-miR-548ai hsa-miR-548ba hsa-miR-570-5p hsa-miR-6814-5p |
5 5 5 5 2 |
tctTTACCTTggg tctTTACCTTggg tctTTACCTTggg tctTTACCTTggg tctttaCCTTGGG |
Created Created Created Created Created |
N N N N N |
0.092 0.092 0.101 0.092 -0.055 |
|||
153167421 | rs139001345 | G | G |
hsa-miR-3162-3p hsa-miR-4740-3p |
6 2 |
tctcgGGTAGGGt TCTCGGGtagggt |
Disrupted Disrupted |
N N |
-0.136 -0.097 |
A |
hsa-miR-454-5p |
6 |
tctcgGATAGGGt |
Created |
N |
-0.054 |
|||
153167810 | rs6785014 | T | A |
hsa-miR-1251-3p hsa-miR-3152-5p hsa-miR-4774-3p hsa-miR-6836-3p |
0 |
gagGCAAAGCcta GAGGCAAAgccta gAGGCAAAgccta GAGGCAAagccta |
Created Created Created Created |
N N N N |
-0.091 -0.359 -0.087 -0.125 |
T |
hsa-miR-31-3p hsa-miR-4633-5p hsa-miR-532-5p |
0 |
gagGCATAGCcta gAGGCATAgccta gAGGCATAgccta |
Disrupted Disrupted Disrupted |
N N N |
-0.184 -0.109 -0.096 |
|||
153168070 | rs3821547 | A | A |
hsa-miR-1252-3p hsa-miR-1253 hsa-miR-3646 hsa-miR-6770-5p |
2 2 2 2 |
cttCTCATTTAgt CTTCTCAtttagt cttcTCATTTAgt CTTCTCAtttagt |
Disrupted Disrupted Disrupted Disrupted |
N N N N |
-0.154 -0.088 0.039 -0.143 |