SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_133487
Gene Symbol: RAD51
Description: Homo sapiens RAD51 homolog (S. cerevisiae) (RAD51), transcript variant 4, mRNA.
Gene Location: chr15(+):40987326-41024356
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Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr15:g.40731824C>A ICGC_89BE1616-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3192 gcgcctgtaCTCCCAGcac
 0 UCUGGGAG m7b (m7b->m6c) -0.159 no TS No effect
hsa-miR-5089 gcgcctgtAATCCCAgcac
 0 GUGGGAUU m7b Created -0.122 -0.182 -0.13
hsa-miR-5095 gcGCCTGTAAtcccagcac
 0 UUACAGGC m8a (m7a->m8a) -0.254 -0.41 -0.55

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
40731817 rs45511893 G G hsa-miR-4438
hsa-miR-5095
hsa-miR-7151-3p
2
2
2
 tcttgcGCCTGTA
tcttgcGCCTGTA
tcttgcGCCTGTA
 Disrupted
Disrupted
Disrupted
N
N
N
 -0.097
-0.107
-0.06
A hsa-miR-4696
hsa-miR-552-3p
hsa-miR-764
1
1
1
 TCTTGCAcctgta
tcttgCACCTGTA
tcttGCACCTGta
 Created
Created
Created
N
N
N
 -0.159
-0.222
-0.185

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