SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_000958
Gene Symbol: PTGER4
Description: Homo sapiens prostaglandin E receptor 4 (subtype EP4) (PTGER4), mRNA.
Gene Location: chr5(+):40680031-40693837
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr5:g.40692453T>C COSN1316037 BN45T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4501 catGTCACATttagctgtg
 2
 UAUGUGAC m7b (m7b->m6b) -0.248000 no TS No effect
hsa-miR-595 catgtCACACTTagctgtg
 0 GAAGUGUG m7b Created no TS -0.358000 -2.270000
hsa-miR-648 catgtCACACTTagctgtg
 0 AAGUGUGC m7a Created NA NA -0.480000
hsa-miR-4501 catGTCACATttagctgtg
 2
 UAUGUGAC m7b (m7b->m6b) -0.248000 no TS No effect
hsa-miR-595 catgtCACACTTagctgtg
 0 GAAGUGUG m7b Created no TS -0.358000 -2.270000
hsa-miR-648 catgtCACACTTagctgtg
 0 AAGUGUGC m7a Created NA NA -0.480000
hsa-miR-4501 catGTCACATttagctgtg
 2
 UAUGUGAC m7b (m7b->m6b) -0.248 no TS No effect
hsa-miR-595 catgtCACACTTagctgtg
 0 GAAGUGUG m7b Created no TS -0.358 -2.27
hsa-miR-648 catgtCACACTTagctgtg
 0 AAGUGUGC m7a Created NA NA -0.48

Mutation Mutation ID Sample Name Cancer Type
chr5:g.40692801T>A COSN5076587 HX22T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-578 actaaagCAAGAAatgtga
 0 CUUCUUGU m6b Created no TS -0.057000 -0.650000


Mutation Mutation ID Sample Name Cancer Type
chr5:g.40692952T>C COSN2105999 RK086_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr5:g.40693007C>T COSN4849890 tumor_4102009 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-144-5p gatTGATATCtataaaata
 3
 GGAUAUCA m7b (m7b->m6b) -0.233000 no TS -0.280000
hsa-miR-340-5p gattgataTTTATAAaata
 0 UUAUAAAG m7a Created no TS 0.050000 -0.950000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.40693364A>G COSN7941725 8016470 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3941 agtGTGTGTAgttttactt
 7
 UUACACAC m7b (m7b->m6b) -0.233000 -0.062000 0.070000
hsa-miR-497-3p agtgtgtGTGGTTTtactt
 0 CAAACCAC m7b Created no TS -0.137000 -5.590000
hsa-miR-548a-3p agtgtgtgtAGTTTTactt
 4
 CAAAACUG m6b Disrupted -0.055000 -0.091000 1.200000
hsa-miR-548aa agtgtgtgTGGTTTTactt
 7
 AAAAACCA m7b Created -0.257000 -0.389000 -6.210000
hsa-miR-548ap-3p agtgtgtgTGGTTTTactt
 7
 AAAAACCA m7b Created -0.257000 -0.389000 -6.460000
hsa-miR-548at-3p agtgtgtgtGGTTTTactt
 8
 CAAAACCG m6b Created -0.100000 -0.146000 -5.230000
hsa-miR-548e agtgtgtgtAGTTTTactt
 4
 AAAAACUG m6b Disrupted -0.050000 -0.082000 0.400000
hsa-miR-548f agtgtgtgtAGTTTTactt
 4
 AAAAACUG m6b Disrupted -0.059000 -0.091000 1.460000
hsa-miR-548t-3p agtgtgtgTGGTTTTactt
 7
 AAAAACCA m7b Created -0.257000 -0.389000 -6.210000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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