SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
||||||||
Home | Search | Help | Download |
RefSeq ID: | NM_017952 |
---|---|
Gene Symbol: | PTCD3 |
Description: | Homo sapiens Pentatricopeptide repeat domain 3 (PTCD3), nuclear gene encoding mitochondrial protein, mRNA. |
Gene Location: | chr2(+):86333304-86369280 |
Browse Associations |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr2:g.86137625A>C | COSN1243772 | HCC98T | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-1285-5p |
agaacTGAGATataccaat |
1 |
GAUCUCAC | m6b | Disrupted | -0.122000 | no TS | No effect | |
hsa-miR-1285-5p |
agaacTGAGATataccaat |
1 |
GAUCUCAC | m6b | Disrupted | -0.122000 | no TS | No effect | |
hsa-miR-1285-5p |
agaacTGAGATataccaat |
1 |
GAUCUCAC | m6b | Disrupted | -0.122 | no TS | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr2:g.86137889C>T | 0_125 | Melanoma | |||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3131 |
cgatgctGTCCTCGtgcga |
6 |
UCGAGGAC | m7b | Disrupted | -0.229 | no TS | No effect | |
hsa-miR-4773 |
cgatgCTGTTCTcgtgcga |
3 |
CAGAACAG | m7b | Created | -0.079 | -0.096 | No effect | |
hsa-miR-5004-5p |
cgatgcTGTCCTCgtgcga |
5 |
UGAGGACA | m7b | Disrupted | -0.088 | no TS |
0.34 |
|
hsa-miR-611 |
cgatgctGTCCTCGtgcga |
6 |
GCGAGGAC | m7b | Disrupted | -0.239 | no TS |
1.17 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr2:g.86138803A>G | COSN15406011 | AOCS-167-16-X | [ovary][NS][other][neoplasm] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr2:g.86139063A>C | COSN10009539 | C0025T | [kidney][NS][other][neoplasm] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr2:g.86139223G>A | COSN5513200 | RK104_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-1228-3p |
tcttcggccAGGTGTGgtg |
0 | UCACACCU | m7b | (m6c->m7b) | no TS | 0.075000 | No effect | |
hsa-miR-941 |
tcttcgGCCGGGTGtggtg |
1 |
CACCCGGC | m8a | Disrupted | -0.113000 | no TS |
1.040000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr2:g.86139395T>G | COSN14655324 | 8069337 | [pancreas][NS][carcinoid-endocrine_tumour][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr2:g.86139767T>C | ICGC_6F4CB940-2A78-11E2-96E7-04FD496BB9B8 | CPCG_0102_Pr_P_P1 | ProstateCancer(OICR,CA) | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-143-5p |
accACTGCACtccagcctg |
0 | GGUGCAGU | m7b | (m6b->m7b) | -0.065 | 0.017 |
-0.42 |
|
hsa-miR-3135b |
accactgcaCTCCAGCCtg |
0 | GGCUGGAG | m8a | (m7b->m8a) | -0.042 | -0.093 |
-2.23 |
|
hsa-miR-3673 |
accactgCATTCCAgcctg |
2 |
AUGGAAUG | m7b | Disrupted | 0.164 | no TS |
0.61 |
|
hsa-miR-613 |
accactgCATTCCagcctg |
2 |
AGGAAUGU | m6b | Disrupted | 0.097 | no TS | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr2:g.86141058T>C | COSN1861504 | RK023_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-10a-3p |
gacaGAATTTactcccagg |
3 |
CAAAUUCG | m6b | Disrupted | 0.123000 | no TS | No effect |
hsa-miR-4452 |
gacaGAATTCActcccagg |
0 | UUGAAUUC | m7b | Created | no TS | 0.041000 |
-0.750000 |
hsa-miR-10a-3p |
gacaGAATTTactcccagg |
3 |
CAAAUUCG | m6b | Disrupted | 0.123000 | no TS | No effect |
hsa-miR-4452 |
gacaGAATTCActcccagg |
0 | UUGAAUUC | m7b | Created | no TS | 0.041000 |
-0.750000 |
hsa-miR-10a-3p |
gacaGAATTTactcccagg |
3 |
CAAAUUCG | m6b | Disrupted | 0.123 | no TS | No effect |
hsa-miR-4452 |
gacaGAATTCActcccagg |
0 | UUGAAUUC | m7b | Created | no TS | 0.041 |
-0.75 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
86139399 | rs4832024 | A | T |
hsa-miR-150-5p hsa-miR-6750-3p |
0 |
ggtgagTTGGGAG gGTGAGTTgggag |
Created Created |
N N |
0.081 0.117 |
A |
hsa-miR-1229-3p hsa-miR-1285-5p hsa-miR-2116-3p hsa-miR-6511a-3p hsa-miR-6511b-3p hsa-miR-6784-3p hsa-miR-6862-3p |
0 |
GGTGAGAtgggag gGTGAGATgggag ggtgagATGGGAG GGTGAGAtgggag GGTGAGAtgggag GGTGAGAtgggag GGTGAGAtgggag |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N |
0.029 0.132 0.04 0.006 0.006 -0.031 -0.032 |
|||
86141427 | rs150937914 | C | C |
hsa-miR-298 hsa-miR-4773 hsa-miR-589-3p |
8 3 3 |
tctgTTCTGCAct tCTGTTCTgcact tcTGTTCTGcact |
Disrupted Disrupted Disrupted |
N N N |
-0.032 -0.079 -0.025 |
G |
hsa-miR-5003-5p |
3 |
tcTGTTGTGcact |
Created |
N |
-0.056 |