| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_006251 |
|---|---|
| Gene Symbol: | PRKAA1 |
| Description: | Homo sapiens protein kinase, AMP-activated, alpha 1 catalytic subunit (PRKAA1), transcript variant 1, mRNA. |
| Gene Location: | chr5(-):40759480-40798297 |
| Browse Associations | |
| Browse Pathways | |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr5:g.40759666T>A | COSN4849891 | tumor_4191799 | [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-141-3p |
ccatggatCAGTGTTctga |
0 | UAACACUG | m7b | Created | no TS | -0.096000 | No effect |
| hsa-miR-200a-3p |
ccatggatCAGTGTTctga |
0 | UAACACUG | m7b | Created | no TS | -0.096000 | No effect |
| hsa-miR-640 |
ccaTGGATCAgtgttctga |
0 | AUGAUCCA | m7b | (m6c->m7b) | no TS | -0.135000 |
-1.710000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr5:g.40759734T>C | COSN6297151 | RK308_C01 | [liver][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-3529-3p |
ttttgaTGTTGTagtgaca |
2 |
AACAACAA | m6b | Disrupted | -0.273000 | -0.244000 | No effect |
| hsa-miR-3913-3p |
tttTGATGTCgtagtgaca |
0 | AGACAUCA | m7b | (m6c->m7b) | no TS | -0.207000 |
-0.300000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr5:g.40760444C>A | COSN8492777 | 296_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-21-5p |
cgctatATAAGCTgttgtg |
0 | UAGCUUAU | m7b | Created | -0.049000 | -0.058000 | No effect |
| hsa-miR-590-5p |
cgctatATAAGCTgttgtg |
0 | GAGCUUAU | m7b | Created | -0.059000 | -0.077000 |
-0.540000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr5:g.40761415T>G | COSN5605475 | RK169_C01 | [liver][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-3148 |
tatatgctTTTTTCCccct |
0 | UGGAAAAA | m7b | Disrupted | 0.104000 | -0.065000 | No effect |
| hsa-miR-4261 |
tatatgctTGTTTCCccct |
0 | AGGAAACA | m7b | Created | no TS | 0.062000 |
-0.100000 |
| hsa-miR-4422 |
tatATGCTTTTttccccct |
11 |
AAAAGCAU | m8a | Disrupted | -0.074000 | -0.089000 | No effect |
| hsa-miR-4668-5p |
tatatgcttTTTTCCCcct |
0 | AGGGAAAA | m7b | (m7b->m6b) | -0.101000 | -0.140000 | No effect |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr5:g.40762025G>C | ICGC_77A42C40-2A78-11E2-96E7-04FD496BB9B8 | CPCG_0102_Pr_P_P1 | ProstateCancer(OICR,CA) | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-1224-3p |
cccaaagtGGTGGGattac |
0 | CCCCACCU | m6b | Disrupted | -0.085 | no TS | No effect |
| hsa-miR-1255b-2-3p |
cccaAAGTGGTgggattac |
0 | AACCACUU | m7b | Disrupted | -0.095 | -0.059 |
0.57 |
| hsa-miR-1260a |
cccaaagtGGTGGGATtac |
0 | AUCCCACC | m8a | Disrupted | -0.127 | no TS | No effect |
| hsa-miR-1260b |
cccaaagtGGTGGGATtac |
0 | AUCCCACC | m8a | Disrupted | -0.136 | no TS |
0.86 |
| hsa-miR-4530 |
cccaaagTGCTGGGattac |
0 | CCCAGCAG | m7a | Created | NA | NA |
-1.1 |