| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_015425 |
|---|---|
| Gene Symbol: | POLR1A |
| Description: | Homo sapiens polymerase (RNA) I polypeptide A, 194kDa (POLR1A), mRNA. |
| Gene Location: | chr2(-):86253450-86333278 |
| Browse Associations | |
| Browse Pathways | |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr2:g.86026694A>G | COSN10009525 | C0056T | [kidney][NS][other][neoplasm] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-182-3p |
cccacacaTAGAACCcagg |
4 |
UGGUUCUA | m7b | Disrupted | -0.089000 | no TS |
0.840000 |
| hsa-miR-23a-5p |
cccacacatGGAACCCagg |
2 |
GGGGUUCC | m7b | (m6b->m7b) | -0.119000 | -0.387000 |
-2.930000 |
| hsa-miR-23b-5p |
cccacacatGGAACCCAgg |
2 |
UGGGUUCC | m8a | (m7a->m8a) | -0.109000 | -0.355000 |
-2.370000 |
| hsa-miR-4716-5p |
cccacACATGGAacccagg |
0 | UCCAUGUU | m7a | Created | no TS | -0.038000 |
-0.080000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr2:g.86026781C>T | COSN14841859 | 8016470 | [pancreas][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-128 |
gccctgcCACTGTGtggcg |
1 |
UCACAGUG | m7b | Disrupted | 0.003000 | no TS | No effect |
| hsa-miR-3681-3p |
gccctgcCACTGTGTggcg |
1 |
ACACAGUG | m8a | Disrupted | -0.007000 | no TS |
1.880000 |
| hsa-miR-5197-5p |
gcccTGCCATTGtgtggcg |
0 | CAAUGGCA | m8a | Created | no TS | 0.004000 |
-1.140000 |
| hsa-miR-5693 |
gccctGCCACTGtgtggcg |
1 |
GCAGUGGC | m7b | Disrupted | -0.088000 | no TS | No effect |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr2:g.86026824A>C | COSN9391693 | AOCS-093-3-6 | [ovary][NS][other][neoplasm] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-363-5p |
tagtccTCCACCCacccaa |
6 |
CGGGUGGA | m7b | Disrupted | -0.391000 | -0.104000 |
4.560000 |
| hsa-miR-4447 |
tagtcctcCCCCCACCcaa |
1 |
GGUGGGGG | m8a | Created | -0.118000 | -0.225000 |
-0.080000 |
| hsa-miR-4472 |
tagtcctcCCCCCACCcaa |
1 |
GGUGGGGG | m8a | Created | -0.118000 | -0.225000 |
-4.910000 |
| hsa-miR-4483 |
tagtcctCCACCCacccaa |
6 |
GGGGUGGU | m6b | Disrupted | -0.219000 | -0.100000 |
2.370000 |
| hsa-miR-4525 |
tagtccTCCCCCCacccaa |
0 | GGGGGGAU | m7a | Created | NA | NA |
-7.510000 |
| hsa-miR-4723-5p |
tagtcCTCCCCCcacccaa |
0 | UGGGGGAG | m7b | Created | no TS | -0.145000 |
-2.420000 |
| hsa-miR-5698 |
tagtcCTCCCCCcacccaa |
0 | UGGGGGAG | m7b | Created | no TS | -0.145000 |
-3.420000 |
| hsa-miR-92a-2-5p |
tagtcctccCCCCACCCaa |
0 | GGGUGGGG | m8a | (m7a->m8a) | no TS | -0.115000 |
0.840000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr2:g.86027377G>T | COSN4893496 | PCSI_0090_Pa_X | [pancreas][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-122-3p |
ccttggtgATGGCGTggcc |
0 | AACGCCAU | m7b | Created | no TS | -0.173000 |
-2.870000 |