| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_003560 |
|---|---|
| Gene Symbol: | PLA2G6 |
| Description: | Homo sapiens phospholipase A2, group VI (cytosolic, calcium-independent) (PLA2G6), transcript variant 2, mRNA. |
| Gene Location: | chr22(-):38507501-38577761 |
| Browse Associations | |
| Browse Pathways | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr22:g.38111677G>A | COSN1261820 | HCC111T | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-3124-3p |
ccatcagctAGGAAAGccc |
0 | ACUUUCCU | m7b | (m6b->m7b) | no TS | -0.016000 |
-2.120000 |
|
| hsa-miR-384 |
ccatcagCTAGGAAagccc |
0 | AUUCCUAG | m7b | Created | no TS | -0.152000 |
-1.930000 |
|
| hsa-miR-5571-3p |
ccatcagCTAGGAaagccc |
0 | GUCCUAGG | m6b | Created | no TS | -0.083000 | No effect | |
| hsa-miR-3124-3p |
ccatcagctAGGAAAGccc |
0 | ACUUUCCU | m7b | (m6b->m7b) | no TS | -0.016000 |
-2.120000 |
|
| hsa-miR-384 |
ccatcagCTAGGAAagccc |
0 | AUUCCUAG | m7b | Created | no TS | -0.152000 |
-1.930000 |
|
| hsa-miR-5571-3p |
ccatcagCTAGGAaagccc |
0 | GUCCUAGG | m6b | Created | no TS | -0.083000 | No effect | |
| hsa-miR-3124-3p |
ccatcagctAGGAAAGccc |
0 | ACUUUCCU | m7b | (m6b->m7b) | no TS | -0.016 |
-2.12 |
|
| hsa-miR-384 |
ccatcagCTAGGAAagccc |
0 | AUUCCUAG | m7b | Created | no TS | -0.152 |
-1.93 |
|
| hsa-miR-5571-3p |
ccatcagCTAGGAaagccc |
0 | GUCCUAGG | m6b | Created | no TS | -0.083 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr22:g.38111728G>A | COSN9165769 | AOCS-059-1-8 | [ovary][NS][other][neoplasm] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1292 |
ctctgctcCGTTCCCtggg |
1 |
UGGGAACG | m7b | Disrupted | -0.160000 | no TS |
5.420000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr22:g.38111811C>A | COSN6692914 | CHC320T | [liver][NS][carcinoma][hepatocellular_carcinoma] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1205 |
agggCCTGCAGggctgcct |
0 | UCUGCAGG | m7b | Created | no TS | -0.009000 | No effect | |
| hsa-miR-3173-5p |
agggcctGCAGGGCtgcct |
0 | UGCCCUGC | m7b | Created | no TS | -0.152000 |
-1.100000 |
|
| hsa-miR-3940-3p |
agggcctgCCGGGCTGcct |
0 | CAGCCCGG | m8a | Disrupted | -0.183000 | no TS |
0.380000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr22:g.38112077A>G | COSN10030398 | C0038T | [kidney][NS][other][neoplasm] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-18a-3p |
ctcccGGGCAGatctgggc |
4 |
ACUGCCCU | m6b | Disrupted | -0.131000 | no TS |
0.910000 |
| hsa-miR-324-3p |
ctcccGGGCAGatctgggc |
4 |
ACUGCCCC | m6b | Disrupted | -0.129000 | no TS |
6.410000 |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 38111810 | rs140193489 | G | G |
hsa-miR-3940-3p |
0 |
cctgCCGGGCTgc |
Disrupted |
N |
-0.183 |
| A |
hsa-miR-1207-5p hsa-miR-221-5p hsa-miR-4736 hsa-miR-4763-3p hsa-miR-6868-5p hsa-miR-7150 hsa-miR-8073 |
0 |
CCTGCCAggctgc ccTGCCAGGctgc CCTGCCAggctgc CCTGCCAggctgc cCTGCCAGgctgc CCTGCCAggctgc ccTGCCAGGctgc |
Created Created Created Created Created Created Created |
N N N N N N N |
-0.083 -0.034 -0.088 -0.066 -0.032 -0.061 -0.09 |
|||
| 38111811 | rs11570770 | A | C |
hsa-miR-3940-3p |
0 |
gcctgCCGGGCTg |
Created |
N |
-0.183 |
| A |
hsa-miR-1205 hsa-miR-3173-5p hsa-miR-6511b-5p hsa-miR-6779-3p hsa-miR-6799-3p hsa-miR-6811-5p |
0 |
gCCTGCAGggctg gcctGCAGGGCtg GCCTGCAgggctg gcctgCAGGGCTg gcctGCAGGGCtg GCCTGCAgggctg |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N |
-0.009 -0.152 -0.074 -0.097 -0.152 -0.046 |
|||
| 38112080 | rs112920700 | G | G |
hsa-miR-1247-3p hsa-miR-18a-3p hsa-miR-1913 hsa-miR-324-3p |
1 4 4 4 |
cTCCCGGGcagat ctcccGGGCAGAt ctcccGGGCAGAt ctcccGGGCAGAt |
Disrupted Disrupted Disrupted Disrupted |
N N N N |
-0.192 -0.131 -0.129 -0.129 |
| T |
hsa-miR-3130-3p hsa-miR-3177-3p hsa-miR-4793-3p |
4 1 4 |
ctcccGTGCAGAt ctcCCGTGCAgat ctcccGTGCAGAt |
Created Created Created |
N N N |
-0.102 -0.211 -0.099 |
|||
| 38112081 | rs11570767 | G | G |
hsa-miR-1247-3p hsa-miR-18a-3p hsa-miR-1913 hsa-miR-324-3p |
1 4 4 4 |
ccTCCCGGGcaga cctcccGGGCAGA cctcccGGGCAGA cctcccGGGCAGA |
Disrupted Disrupted Disrupted Disrupted |
N N N N |
-0.192 -0.131 -0.129 -0.129 |
| A |
hsa-miR-1254 hsa-miR-1273h-5p hsa-miR-149-3p hsa-miR-30b-3p hsa-miR-3116 hsa-miR-3192-5p hsa-miR-3689a-3p hsa-miR-3689b-3p hsa-miR-3689c hsa-miR-4728-5p hsa-miR-5001-3p hsa-miR-661 hsa-miR-6779-5p hsa-miR-6780a-5p hsa-miR-6785-5p hsa-miR-6799-5p hsa-miR-6883-5p hsa-miR-7106-5p |
1 1 1 1 1 1 1 1 1 1 4 1 1 1 1 1 1 1 |
cctcCCAGGCAga CCTCCCAggcaga CCTCCCAggcaga CCTCCCAggcaga cctcCCAGGCAga cCTCCCAGgcaga CCTCCCAggcaga CCTCCCAggcaga CCTCCCAggcaga CCTCCCAggcaga cctcccAGGCAGA cctCCCAGGCAga CCTCCCAggcaga CCTCCCAggcaga CCTCCCAggcaga CCTCCCAggcaga CCTCCCAggcaga CCTCCCAggcaga |
Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created |
N N N N N N N N N N N N N N N N N N |
-0.151 -0.133 -0.211 -0.086 -0.151 -0.098 -0.077 -0.077 -0.077 -0.209 -0.103 -0.442 -0.114 -0.105 -0.208 -0.122 -0.208 -0.102 |