SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_181839 |
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Gene Symbol: | PKIA |
Description: | Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor alpha (PKIA), transcript variant 1, mRNA. |
Gene Location: | chr8(+):79428335-79517502 |
Browse Associations |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr8:g.78602500C>A | COSN8519484 | 4537_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3153 |
cagtCTTTCCCCttgctca |
6 |
GGGGAAAG | m8a | Disrupted | -0.137000 | -0.042000 |
0.010000 |
hsa-miR-4761-5p |
cagtctttCACCTTGctca |
0 | ACAAGGUG | m7b | Created | no TS | -0.159000 |
-0.820000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr8:g.78602689C>A | COSN9681543 | AOCS-155-3-5 | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1270 |
aactTCTCCAacataatat |
12 |
CUGGAGAU | m6b | Created | -0.205000 | -0.278000 | No effect |
hsa-miR-299-3p |
aacttctCCCACATAatat |
1 |
UAUGUGGG | m8a | Disrupted | -0.295000 | no TS |
0.080000 |
hsa-miR-30c-1-3p |
aactTCTCCCAcataatat |
0 | CUGGGAGA | m7b | Disrupted | -0.269000 | -0.105000 | No effect |
hsa-miR-30c-2-3p |
aactTCTCCCAcataatat |
0 | CUGGGAGA | m7b | Disrupted | -0.287000 | -0.123000 | No effect |
hsa-miR-4296 |
aacttctCCCACATaatat |
0 | AUGUGGGC | m7a | Disrupted | NA | NA | No effect |
hsa-miR-4491 |
aacttctcCCACATaatat |
7 |
AAUGUGGA | m6b | Disrupted | -0.141000 | -0.041000 | No effect |
hsa-miR-4516 |
aaCTTCTCCCacataatat |
1 |
GGGAGAAG | m8a | (m8a->m7a) | -0.077000 | -0.164000 | No effect |
hsa-miR-4531 |
aacTTCTCCAacataatat |
0 | AUGGAGAA | m7b | (m6b->m7b) | no TS | -0.173000 | No effect |
hsa-miR-4657 |
aacttctcCCACATaatat |
7 |
AAUGUGGA | m6b | Disrupted | -0.139000 | -0.032000 | No effect |
hsa-miR-4769-5p |
aacttcTCCCACataatat |
1 |
GGUGGGAU | m6b | Disrupted | -0.154000 | no TS |
0.010000 |
hsa-miR-4781-3p |
aacttctCCAACATaatat |
4 |
AAUGUUGG | m7b | Created | -0.247000 | -0.463000 |
-0.070000 |
hsa-miR-620 |
aactTCTCCAacataatat |
12 |
AUGGAGAU | m6b | Created | -0.186000 | -0.259000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr8:g.78602908A>G | COSN7677886 | ASHPC_0003_Pa_P_2 | [pancreas][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr8:g.78602912C>A | COSN9681544 | AOCS-091-3-0 | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3657 |
tgtGGACACAaatcacaaa |
0 | UGUGUCCC | m7a | (m6a->m7a) | no TS | -0.085000 |
0.830000 |
hsa-miR-4669 |
tgtGGACACAaatcacaaa |
0 | UGUGUCCG | m7a | (m6a->m7a) | no TS | -0.087000 |
0.010000 |
hsa-miR-5010-3p |
tgtggACACAAAtcacaaa |
11 |
UUUUGUGU | m7b | Created | 0.068000 | 0.108000 | No effect |
hsa-miR-509-3p |
tgtggacACCAATCAcaaa |
14 |
UGAUUGGU | m8a | Disrupted | -0.084000 | no TS |
0.380000 |
hsa-miR-592 |
tgtgGACACAAatcacaaa |
0 | UUGUGUCA | m7a | Created | no TS | -0.049000 | No effect |
hsa-miR-599 |
tgtgGACACAAatcacaaa |
0 | GUUGUGUC | m7b | Created | no TS | -0.041000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr8:g.78603280C>T | COSN9681545 | AOCS-155-3-5 | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4417 |
aataacgAGCCCACttagc |
6 |
GGUGGGCU | m7b | Disrupted | -0.042000 | no TS |
0.860000 |
hsa-miR-4674 |
aataacGAGCCCActtagc |
5 |
CUGGGCUC | m7b | Disrupted | -0.036000 | no TS |
2.470000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr8:g.78603366C>T | COSN8519485 | 2275_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3128 |
gtggttgTGCCAGAaactc |
2 |
UCUGGCAA | m7a | Disrupted | -0.032000 | no TS |
-0.710000 |
hsa-miR-3660 |
gtggttgTGTCAGaaactc |
16 |
ACUGACAG | m6b | Created | -0.078000 | -0.057000 |
-0.550000 |
hsa-miR-4256 |
gtggttgtGTCAGAaactc |
0 | AUCUGACC | m6b | Created | no TS | 0.029000 |
-0.020000 |
hsa-miR-4526 |
gtggttgTGTCAGaaactc |
16 |
GCUGACAG | m6b | Created | -0.081000 | -0.053000 | No effect |
hsa-miR-4720-5p |
gtggttgTGCCAGaaactc |
2 |
CCUGGCAU | m6b | Disrupted | -0.023000 | no TS |
0.090000 |
hsa-miR-4762-3p |
gtggttgtgTCAGAAactc |
0 | CUUCUGAU | m6b | Created | no TS | 0.097000 |
-0.020000 |
hsa-miR-4799-3p |
gtggttgTGCCAGaaactc |
2 |
ACUGGCAU | m6b | Disrupted | -0.030000 | no TS |
5.810000 |
hsa-miR-5588-5p |
gtggttgTGCCAGaaactc |
2 |
ACUGGCAU | m6b | Disrupted | -0.027000 | no TS |
0.020000 |
hsa-miR-642a-3p |
gtggtTGTGTCagaaactc |
0 | AGACACAU | m6b | Created | no TS | 0.045000 | No effect |
hsa-miR-642b-3p |
gtggtTGTGTCagaaactc |
0 | AGACACAU | m6b | Created | no TS | 0.045000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr8:g.78603464A>T | COSN8326973 | SS6003317 | [oesophagus][NS][carcinoma][adenocarcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-129-1-3p |
aatAAGGGCTTggttgcat |
18 |
AAGCCCUU | m8a | Created | -0.265000 | -0.336000 |
0.700000 |
hsa-miR-129-2-3p |
aatAAGGGCTTggttgcat |
18 |
AAGCCCUU | m8a | Created | -0.265000 | -0.336000 |
0.490000 |
hsa-miR-938 |
aaTAAGGGCAtggttgcat |
3 |
UGCCCUUA | m8a | (m8a->m7a) | -0.073000 | -0.053000 |
0.900000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr8:g.78603760A>T | COSN9681546 | AOCS-104-1-6 | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4282 |
tgtgAATTTTAacttctct |
0 | UAAAAUUU | m7a | Created | 0.620000 | 0.834000 | No effect |
hsa-miR-4670-3p |
tgtgaatttTAACTTCtct |
0 | UGAAGUUA | m7b | (m6c->m7b) | no TS | 0.001000 |
-0.010000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr8:g.78604073A>G | COSN8103313 | 8066464 | [pancreas][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4659a-5p |
tgcttattCATGGCAtctt |
0 | CUGCCAUG | m7b | Disrupted | -0.167000 | no TS |
0.470000 |
hsa-miR-4659b-5p |
tgcttattCATGGCAtctt |
0 | UUGCCAUG | m7b | Disrupted | -0.167000 | no TS |
0.450000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr8:g.78604367T>G | COSN14496065 | 8069334 | [pancreas][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3605-3p |
gtgatgaACGGAGGatttg |
0 | CCUCCGUG | m7a | Created | NA | NA |
0.110000 |
hsa-miR-4277 |
gtgatGAACTGaggatttg |
1 |
GCAGUUCU | m6b | Disrupted | -0.015000 | no TS | No effect |
hsa-miR-5000-5p |
gtgaTGAACTGaggatttg |
0 | CAGUUCAG | m7a | Disrupted | NA | NA | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr8:g.78605111C>T | COSN4942055 | PD4103a | [breast][NS][carcinoma][ductal_carcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-376a-3p |
ggaaaggaTCTATGATtta |
4 |
AUCAUAGA | m8a | Disrupted | -0.213000 | no TS |
-0.320000 |
hsa-miR-376b |
ggaaaggaTCTATGATtta |
4 |
AUCAUAGA | m8a | Disrupted | -0.213000 | no TS |
-0.580000 |
hsa-miR-500a-5p |
ggaAAGGATTtatgattta |
0 | UAAUCCUU | m7b | (m6b->m7b) | no TS | -0.195000 |
-0.880000 |
hsa-miR-501-5p |
ggAAAGGATTtatgattta |
8 |
AAUCCUUU | m8a | (m7a->m8a) | -0.120000 | -0.147000 |
-0.020000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr8:g.78605156A>G | COSN9681547 | AOCS-112-1-2 | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-106a-3p |
tctttaATTGCAagagtgg |
4 |
CUGCAAUG | m6b | Created | -0.139000 | -0.228000 | No effect |
hsa-miR-2054 |
tctttaATTACAagagtgg |
2 |
CUGUAAUA | m6b | Disrupted | -0.049000 | no TS |
0.320000 |
hsa-miR-643 |
tctttaatTACAAGagtgg |
2 |
ACUUGUAU | m6b | Disrupted | -0.093000 | no TS |
0.010000 |