SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_000926
Gene Symbol: PGR
Description: Homo sapiens progesterone receptor (PGR), transcript variant 2, mRNA.
Gene Location: chr11(-):100900354-101000544
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr11:g.101029836C>T COSN7077208 8016470 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1273f tgcaaaatcCCATCTCtgt
2
GGAGAUGG m7b (m7b->m6b) -0.221000 0.035000 0.250000
hsa-miR-1290 tgcAAAATCCcatctctgt
2
UGGAUUUU m7b (m7b->m6c) 0.021000 0.105000 No effect
hsa-miR-143-3p tgcaaaatcTCATCTCtgt
3
UGAGAUGA m7b (m6b->m7b) 0.000000 -0.189000 No effect
hsa-miR-4770 tgcaaaatcTCATCTCtgt
3
UGAGAUGA m7b (m6b->m7b) 0.000000 -0.180000 -0.060000
hsa-miR-5089 tgcaaAATCCCAtctctgt
2
GUGGGAUU m7b Disrupted -0.176000 0.044000 0.040000
hsa-miR-5186 tgcaaAATCTCatctctgt
4
AGAGAUUG m6b Created 0.067000 -0.027000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.101029972T>A COSN8532864 tumor_4135099 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3169 aggtgaaaCAGTCCTttca
5
UAGGACUG m7b Created -0.035000 -0.262000 -0.150000
hsa-miR-452-5p aggtgAAACAGTcctttca
0 AACUGUUU m7b Created -0.149000 -0.154000 No effect
hsa-miR-4676-3p aggtgAAACAGTcctttca
0 CACUGUUU m7b Created -0.139000 -0.181000 -0.540000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.101030238T>C COSN1509098 RK001_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3161 gttgCTTATCAGtaaaact
0 CUGAUAAG m8a Created 0.280000 0.234000 No effect
hsa-miR-3161 gttgCTTATCAGtaaaact
0 CUGAUAAG m8a Created 0.28 0.234 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.101030302G>C COSN5294538 RK140_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5583-3p cacatggtaCATATTCaca
0 GAAUAUGG m7a (m6a->m7a) -0.312000 -0.312000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.101030742T>C COSN6606506 CHC322T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4422 tagaccATGCTTTTcgctt
2
AAAAGCAU m8a Created 0.201000 0.297000 -0.020000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.101030778C>T COSN7077209 8058184 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5009-5p tgcttAAGTCCAcctttta
0 UUGGACUU m7b Disrupted -0.026000 0.037000 0.020000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.101031512T>C COSN5294539 RK143_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-370 ggtgagCAGCAGGttgaag
1
GCCUGCUG m7b Created -0.035000 -0.012000 No effect
hsa-miR-4714-3p ggtgagcagTAGGTTGaag
2
CCAACCUA m7b (m7b->m6b) 0.040000 0.027000 No effect
hsa-miR-490-3p ggtgagcagCAGGTTGaag
7
CAACCUGG m7a (m6a->m7a) 0.020000 0.020000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.101031564C>A COSN14545670 8069331 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-224-5p acattGTGACTTcatgagc
0 CAAGUCAC m7b Disrupted -0.010000 no TS 3.180000
hsa-miR-4452 acattgtGAATTCAtgagc
2
UUGAAUUC m7b Created 0.121000 0.217000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.101031844G>A COSN5294540 RK030_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-182-3p tagattctTAGAACCtcga
0 UGGUUCUA m7b Created -0.028000 -0.023000 No effect
hsa-miR-3653 tagaTTCTTAGaacctcga
3
CUAAGAAG m7a Created 0.105000 0.105000 -0.010000
hsa-miR-4263 tagattCTTAGAAcctcga
2
AUUCUAAG m7b Created 0.132000 0.230000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.101031955G>T COSN8212228 PCSI_0083_Pa_P_526 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3661 caaagtCCAGGTCtataca
3
UGACCUGG m7b Disrupted -0.147000 -0.056000 3.950000
hsa-miR-3684 caaagtccAGGTCTAtaca
3
UUAGACCU m7b Disrupted -0.039000 -0.059000 0.030000
hsa-miR-3690 caaaGTCCAGGTctataca
2
ACCUGGAC m8a Disrupted -0.069000 no TS 3.440000
hsa-miR-378a-3p caaAGTCCAGgtctataca
4
ACUGGACU m7b (m7b->m6c) -0.217000 -0.193000 0.030000
hsa-miR-378b caaAGTCCAGgtctataca
4
ACUGGACU m7b (m7b->m6c) -0.206000 -0.163000 1.340000
hsa-miR-378c caaAGTCCAGgtctataca
4
ACUGGACU m7b (m7b->m6c) -0.217000 -0.193000 0.390000
hsa-miR-378d caaAGTCCAGgtctataca
4
ACUGGACU m7b (m7b->m6c) -0.217000 -0.193000 0.540000
hsa-miR-378e caaAGTCCAGgtctataca
4
ACUGGACU m7b (m7b->m6c) -0.217000 -0.193000 1.050000
hsa-miR-378f caaAGTCCAGgtctataca
4
ACUGGACU m7b (m7b->m6c) -0.205000 -0.181000 0.350000
hsa-miR-378h caaAGTCCAGgtctataca
4
ACUGGACU m7b (m7b->m6c) -0.220000 -0.196000 0.780000
hsa-miR-378i caaAGTCCAGgtctataca
4
ACUGGACU m7b (m7b->m6c) -0.217000 -0.193000 4.870000
hsa-miR-422a caaAGTCCAGgtctataca
4
ACUGGACU m7b (m7b->m6c) -0.227000 -0.193000 0.050000
hsa-miR-4802-3p caaagTCCATGTctataca
2
UACAUGGA m7b Created -0.259000 -0.203000 -0.010000
hsa-miR-619 caaagTCCAGGTCtataca
2
GACCUGGA m8a Disrupted 0.001000 0.044000 0.240000
hsa-miR-631 caaagtCCAGGTCTataca
3
AGACCUGG m8a Disrupted -0.187000 -0.096000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.101032193T>C COSN5891004 RK216_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4781-3p tggaagataCAACATagga
0 AAUGUUGG m6b Created no TS 0.088000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.101032480A>T COSN5891005 RK211_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4704-3p tggatgatGTGACTGAaga
1
UCAGUCAC m8a Created 0.002000 -0.029000 -3.240000
hsa-miR-622 tggatgatgAGACTGaaga
2
ACAGUCUG m6b Disrupted 0.048000 no TS No effect


Mutation Mutation ID Sample Name Cancer Type
chr11:g.101032716A>C COSN15247732 LP6007420-DNA_A01 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Mutation Mutation ID Sample Name Cancer Type
chr11:g.101033440A>C COSN8937629 SS6003149 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr11:g.101033558A>T COSN10076321 C0091T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1261 ataacaattTTATCCAcac
0 AUGGAUAA m7b (m6b->m7b) -0.176000 -0.197000 No effect
hsa-miR-3163 ataacaATTTTATccacac
6
UAUAAAAU m7b Created 0.955000 1.186000 No effect
hsa-miR-3201 ataacaattATATCCacac
2
GGGAUAUG m6b Disrupted 0.036000 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.101034453A>G COSN1509099 RK209_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3910 tcaatacATGCCTTctctg
4
AAAGGCAU m7b Created -0.013000 0.015000 No effect
hsa-miR-3924 tcaATACATAccttctctg
2
AUAUGUAU m7b (m7b->m6c) 0.191000 0.091000 0.060000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.101034495T>A COSN1509100 RK180_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-200a-5p ggtaGTAAGATaaacacag
2
CAUCUUAC m7b Created 0.059000 0.116000 -0.040000
hsa-miR-200b-5p ggtaGTAAGATaaacacag
2
CAUCUUAC m7b Created 0.059000 0.127000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.101034920A>G COSN7077210 8051974 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3692-3p ggctgaGTGGAAacaacaa
0 GUUCCACA m6b Created no TS 0.055000 No effect
hsa-miR-4436b-5p ggctgAGTGGAaacaacaa
2
GUCCACUU m6b Created 0.056000 0.065000 No effect
hsa-miR-5096 ggctgaGTGAAAacaacaa
3
GUUUCACC m6b Disrupted -0.019000 -0.134000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.101035015G>C COSN8728380 AOCS-120-3-6 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-32-3p tcCTAAATTGcttatcctt
0 CAAUUUAG m8a (m8a->m7b) 1.069000 1.069000 -0.010000
hsa-miR-3942-5p tcctaaATTGCTTatcctt
0 AAGCAAUA m7a Disrupted 0.028000 0.028000 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.101035865A>T COSN8728381 AOCS-091-3-0 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1183 atattCTACAGTGaaagca
2
CACUGUAG m8a Disrupted -0.045000 0.028000 0.260000
hsa-miR-1208 atattctACAGTGAaagca
2
UCACUGUU m7a Disrupted 0.029000 no TS 0.110000
hsa-miR-128 atattctACTGTGAaagca
2
UCACAGUG m7a Created 0.126000 0.170000 -0.100000
hsa-miR-181b-3p atattctaCAGTGAaagca
2
CUCACUGA m6b Disrupted 0.027000 no TS 1.480000
hsa-miR-27a-3p atattctACTGTGAAagca
1
UUCACAGU m8a Created 0.092000 0.109000 -0.130000
hsa-miR-27b-3p atattctACTGTGAAagca
1
UUCACAGU m8a Created 0.092000 0.109000 -0.270000
hsa-miR-3681-3p atattctACTGTGaaagca
2
ACACAGUG m6b Created 0.088000 0.129000 No effect
hsa-miR-4420 atattctaCAGTGAaagca
2
GUCACUGA m6b Disrupted 0.016000 no TS 3.180000
hsa-miR-513a-5p atattctaCTGTGAAagca
1
UUCACAGG m7a Created 0.126000 0.170000 -0.030000
hsa-miR-936 atatTCTACTGTgaaagca
0 ACAGUAGA m8a Created no TS -0.028000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.101036670A>T COSN5891006 RK181_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-548c-3p ggatttaATTTTTaaggct
0 CAAAAAUC m6b Created 2.024000 2.252000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.101036842C>T COSN7077211 8062306 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-32-3p gataTAAATTatttccacc
0 CAAUUUAG m6b Created 1.069000 1.226000 No effect
hsa-miR-5093 gatataaatCATTTCCacc
7
AGGAAAUG m7b (m7b->m6b) 0.131000 0.145000 No effect
hsa-miR-5692a gatataaATTATTTccacc
2
CAAAUAAU m7b Created 1.531000 1.709000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.101037255G>T COSN7077213 8012342 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-500a-3p tactaggtAGGTGCAaaac
3
AUGCACCU m7b Disrupted -0.142000 no TS No effect
hsa-miR-5589-3p tactaggtATGTGCAaaac
1
UGCACAUG m7a Created -0.037000 -0.043000 No effect


Mutation Mutation ID Sample Name Cancer Type
chr11:g.101037537G>T COSN1509101 RK208_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr11:g.101037763C>T COSN1509102 RK067_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3613-3p tgcataTTTTTGTacccat
6
ACAAAAAA m7a Created 0.744000 0.744000 No effect
hsa-miR-3613-3p tgcataTTTTTGTacccat
0 ACAAAAAA m7a Created 0.744 0.744 -2.61


Mutation Mutation ID Sample Name Cancer Type
chr11:g.101037933A>T COSN1509103 RK189_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Mutation Mutation ID Sample Name Cancer Type
chr11:g.101038352T>C COSN1509104 RK006_C02 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr11:g.101038556A>T COSN1509105 RK084_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3529-3p aatagaTTGTTGTTcttca
3
AACAACAA m8a Created 0.055000 -0.058000 No effect
hsa-miR-3529-3p aatagaTTGTTGTTcttca
0 AACAACAA m8a Created 0.055 -0.058 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.101038557G>T COSN1509106 RK084_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4803 aaatagatTTATGTTcttc
0 UAACAUAA m7b Created 0.040000 -0.019000 No effect
hsa-miR-4803 aaatagatTTATGTTcttc
0 UAACAUAA m7b Created 0.04 -0.019 -1.17

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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