SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_000318
Gene Symbol: PEX2
Description: Homo sapiens peroxisomal biogenesis factor 2 (PEX2), transcript variant 1, mRNA.
Gene Location: chr8(-):77892493-77912524
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr8:g.76980383A>T COSN15394147 AOCS-092-1-6 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3138 catttcaaaTGTCCACAtt
2
UGUGGACA m8a (m7a->m8a) -0.199000 -0.465000 1.910000
hsa-miR-5009-5p catttcaaAAGTCCAcatt
3
UUGGACUU m7b Disrupted -0.360000 -0.129000 3.100000
hsa-miR-3138 catttcaaaTGTCCACAtt
2
UGUGGACA m8a (m7a->m8a) -0.199000 -0.465000 1.910000
hsa-miR-5009-5p catttcaaAAGTCCAcatt
3
UUGGACUU m7b Disrupted -0.360000 -0.129000 3.100000


Mutation Mutation ID Sample Name Cancer Type
chr8:g.76980522T>C COSN9680663 AOCS-166-1-2 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr8:g.76980581A>C COSN6363646 RK134_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4505 cattcctgaCCCAGCCact
1
AGGCUGGG m7b (m6b->m7b) -0.426000 -0.696000 -0.030000
hsa-miR-5589-5p cattcctgACCCAGCCact
1
GGCUGGGU m8a Created -0.097000 -0.303000 -0.260000

Mutation Mutation ID Sample Name Cancer Type
chr8:g.76981223T>G ICGC_E5078106-2A78-11E2-9A67-27FD496BB9B8 CPCG_0103_Pr_P_P7 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1224-3p tcccaaagtGGTGGGatta
0 CCCCACCU m6b Created no TS -0.071 -0.06
hsa-miR-1255b-2-3p tcccaAAGTGGTgggatta
0 AACCACUU m7b Created no TS 0.015 -0.32
hsa-miR-1260a tcccaaagtGGTGGGATta
0 AUCCCACC m8a (m7a->m8a) no TS -0.104 -0.11
hsa-miR-1260b tcccaaagtGGTGGGATta
0 AUCCCACC m8a (m7a->m8a) no TS -0.113 -0.56
hsa-miR-188-3p tcccaaagtTGTGGGAtta
0 CUCCCACA m7b (m7b->m6b) -0.112 no TS 3.26

Mutation Mutation ID Sample Name Cancer Type
chr8:g.76981498A>T COSN8102028 8033691 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-508-3p tataTACAATCgtctttgt
0 UGAUUGUA m7b Created no TS -0.109000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr8:g.76981659A>G COSN14702585 CHC433T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-338-5p aaaatTATTGTaatgcata
2
AACAAUAU m6b Created 0.105000 0.177000 -1.830000
hsa-miR-369-3p aaaatTATTATaatgcata
0 AAUAAUAC m6b Disrupted -0.044000 -0.151000 0.030000
hsa-miR-374a-5p aaaatTATTATAAtgcata
1
UUAUAAUA m8a Disrupted 0.131000 no TS 0.260000
hsa-miR-374b-5p aaaatTATTATAatgcata
1
AUAUAAUA m7b Disrupted 0.152000 no TS 0.190000
hsa-miR-4528 aaaattatTATAATGcata
3
UCAUUAUA m7b Disrupted 0.020000 no TS 0.120000
hsa-miR-5692b aaaatTATTATaatgcata
6
AAUAAUAU m6b Disrupted -0.003000 -0.117000 0.170000
hsa-miR-5692c aaaatTATTATaatgcata
6
AAUAAUAU m6b Disrupted -0.003000 -0.117000 0.190000

Mutation Mutation ID Sample Name Cancer Type
chr8:g.76981874G>A COSN9680664 AOCS-105-1-9 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-16-1-3p taagATACTGaagaagttt
2
CCAGUAUU m6b Disrupted -0.068000 -0.097000 No effect
hsa-miR-222-5p taagaTACTGAagaagttt
1
CUCAGUAG m6b Disrupted 0.029000 no TS No effect
hsa-miR-4778-3p taagatactGAAGAAGttt
2
UCUUCUUC m7b (m7b->m6b) -0.007000 no TS 3.620000

Mutation Mutation ID Sample Name Cancer Type
chr8:g.76982407G>A COSN195763 PD4199a [NS][NS][NS][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-498 ggcaGCTTGAAAgtgaggc
1
UUUCAAGC m8a Created -0.062000 -0.117000 No effect
hsa-miR-498 ggcaGCTTGAAAgtgaggc
0 UUUCAAGC m8a Created -0.062 -0.117 No effect

Mutation Mutation ID Sample Name Cancer Type
chr8:g.76982447G>A COSN6363647 RK308_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-142-5p ccacagttgACTTTATatt
2
CAUAAAGU m7b (m6b->m7b) 0.064000 0.047000 -0.240000
hsa-miR-5590-3p ccacagttgACTTTATatt
2
AAUAAAGU m7b (m6b->m7b) 0.048000 0.016000 -0.010000
hsa-miR-9-3p ccacagttgGCTTTATatt
0 AUAAAGCU m7a (m7a->m6a) NA NA No effect

Mutation Mutation ID Sample Name Cancer Type
chr8:g.76982549G>A COSN2290366 RK091_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4284 attacagacGTGAGCCact
2
GGGCUCAC m7b (m7b->m6b) -0.206000 -0.081000 -0.030000
hsa-miR-654-3p attaCAGACATgagccact
0 UAUGUCUG m7b Created no TS -0.068000 -0.380000

Mutation Mutation ID Sample Name Cancer Type
chr8:g.76982744G>C ICGC_7F59DA02-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-25-5p cactgcaacCTCCGCCTcc
0 AGGCGGAG m8a (m7a->m8a) no TS -0.185 No effect
hsa-miR-377-5p cactgCAACCTCcgcctcc
0 AGAGGUUG m7b Created no TS -0.014 No effect
hsa-miR-658 cactgcaaCCTCCGCCtcc
0 GGCGGAGG m8a Created no TS -0.224 No effect

Mutation Mutation ID Sample Name Cancer Type
chr8:g.76982943G>C COSN9680665 AOCS-141-3-2 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4307 gattctAAACATaaagatt
2
AAUGUUUU m6b Created 0.053000 0.066000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr8:g.76983032A>G COSN2290367 RK157_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3117-5p caattttTAGTGTCaagaa
0 AGACACUA m7b Created no TS -0.388000 -4.420000
hsa-miR-4704-5p caattttTAGTGTCaagaa
2
GACACUAG m7a Created -0.121000 -0.121000 -0.010000
hsa-miR-489 caatttttaATGTCAagaa
0 GUGACAUC m6b Disrupted -0.116000 no TS 0.010000
hsa-miR-514a-3p caatttttaGTGTCAAgaa
0 AUUGACAC m7b (m6b->m7b) no TS -0.252000 -4.490000
hsa-miR-514b-3p caatttttaGTGTCAAgaa
0 AUUGACAC m7b (m6b->m7b) no TS -0.252000 -1.740000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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