SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_033135
Gene Symbol: PDGFD
Description: Homo sapiens platelet derived growth factor D (PDGFD), transcript variant 1, mRNA.
Gene Location: chr11(-):103777913-104035027
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr11:g.103907486A>T COSN8729258 AOCS-064-3-3 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-130a-3p atcttTTGCACTtctaaca
 10
 CAGUGCAA m7b Disrupted -0.213000 no TS No effect
hsa-miR-130b-3p atcttTTGCACTtctaaca
 10
 CAGUGCAA m7b Disrupted -0.203000 no TS No effect
hsa-miR-19a-3p atctTTTGCACttctaaca
 1
 UGUGCAAA m7b Disrupted -0.182000 no TS 0.040000
hsa-miR-19b-3p atctTTTGCACttctaaca
 1
 UGUGCAAA m7b Disrupted -0.182000 no TS 0.030000
hsa-miR-301a-3p atcttTTGCACTtctaaca
 10
 CAGUGCAA m7b Disrupted -0.203000 no TS No effect
hsa-miR-301b atcttTTGCACTtctaaca
 10
 CAGUGCAA m7b Disrupted -0.213000 no TS 0.010000
hsa-miR-3666 atcttTTGCACTtctaaca
 10
 CAGUGCAA m7b Disrupted -0.231000 no TS No effect
hsa-miR-4295 atcttTTGCACTtctaaca
 10
 CAGUGCAA m7b Disrupted -0.166000 no TS No effect
hsa-miR-454-3p atcttTTGCACTtctaaca
 10
 UAGUGCAA m7b Disrupted -0.194000 no TS 0.010000
hsa-miR-4795-5p atcttttgCACTTCTaaca
 0 AGAAGUGG m7a Disrupted NA NA -2.120000
hsa-miR-5197-3p atcttttgCTCTTCTaaca
 0 AAGAAGAG m7b Created no TS -0.234000 0.040000
hsa-miR-519a-3p atctttTGCACTTctaaca
 9
 AAAGUGCA m7b Disrupted -0.391000 -0.185000 No effect
hsa-miR-519b-3p atctttTGCACTTctaaca
 9
 AAAGUGCA m7b Disrupted -0.391000 -0.185000 No effect
hsa-miR-519c-3p atctttTGCACTTctaaca
 9
 AAAGUGCA m7b Disrupted -0.391000 -0.185000 No effect
hsa-miR-548aj-5p atCTTTTGCActtctaaca
 1
 UGCAAAAG m8a (m8a->m7b) -0.238000 -0.154000 0.010000
hsa-miR-548aw atcTTTTGCACttctaaca
 1
 GUGCAAAA m8a Disrupted -0.060000 0.007000 0.160000
hsa-miR-548g-5p atCTTTTGCActtctaaca
 1
 UGCAAAAG m8a (m8a->m7b) -0.238000 -0.154000 0.010000
hsa-miR-548p atcTTTTGCTcttctaaca
 9
 UAGCAAAA m7b (m6c->m7b) -0.040000 -0.125000 No effect
hsa-miR-548x-5p atCTTTTGCActtctaaca
 1
 UGCAAAAG m8a (m8a->m7b) -0.238000 -0.154000 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.103907510C>A COSN1125551 HX15T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4434 aaaCTTCTCCcttggttac
 8
 AGGAGAAG m7b (m7b->m6c) -0.203000 no TS 2.030000
hsa-miR-4516 aaaCTTCTCCCttggttac
 8
 GGGAGAAG m8a Disrupted -0.166000 no TS 0.170000
hsa-miR-5703 aaaCTTCTCCcttggttac
 8
 AGGAGAAG m7b (m7b->m6c) -0.203000 no TS 3.840000
hsa-miR-4434 aaaCTTCTCCcttggttac
 0 AGGAGAAG m7b (m7b->m6c) -0.203 no TS 2.03
hsa-miR-4516 aaaCTTCTCCCttggttac
 0 GGGAGAAG m8a Disrupted -0.166 no TS 0.17
hsa-miR-5703 aaaCTTCTCCcttggttac
 0 AGGAGAAG m7b (m7b->m6c) -0.203 no TS 3.84

Mutation Mutation ID Sample Name Cancer Type
chr11:g.103907515T>C COSN15114030 SM-4B296 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4434 tattaaaaCTTCTCCcttg
 8
 AGGAGAAG m7b Disrupted -0.203000 no TS 2.100000
hsa-miR-4516 tattaaaaCTTCTCCCttg
 8
 GGGAGAAG m8a Disrupted -0.166000 no TS 0.170000
hsa-miR-5703 tattaaaaCTTCTCCcttg
 8
 AGGAGAAG m7b Disrupted -0.203000 no TS 4.420000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.103908426G>A COSN1510295 RK137_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-376a-3p taaTCTATGAagcttgctt
 0 AUCAUAGA m7b (m6c->m7b) no TS -0.027000 -0.250000
hsa-miR-376b taaTCTATGAagcttgctt
 0 AUCAUAGA m7b (m6c->m7b) no TS -0.038000 -0.100000
hsa-miR-376a-3p taaTCTATGAagcttgctt
 0 AUCAUAGA m7b (m6c->m7b) no TS -0.027 -0.25
hsa-miR-376b taaTCTATGAagcttgctt
 0 AUCAUAGA m7b (m6c->m7b) no TS -0.038 -0.1

Mutation Mutation ID Sample Name Cancer Type
chr11:g.103908754C>A COSN6606627 CHC433T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-33a-3p aaaagtgAACATTGaaaca
 0 CAAUGUUU m7a Disrupted NA NA 4.360000
hsa-miR-5096 aaaaGTGAAAattgaaaca
 0 GUUUCACC m6b Created 0.016000 0.024000 -0.220000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.103908836A>G COSN15109689 SM-4B296 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1200 atccttTCAGGAatggcat
 0 CUCCUGAG m6b Created no TS -0.029000 No effect
hsa-miR-3140-5p atcctTTCAGGaatggcat
 0 ACCUGAAU m6b Created no TS -0.023000 -0.170000
hsa-miR-378a-5p atccttTCAGGAatggcat
 0 CUCCUGAC m6b Created no TS -0.032000 -2.840000
hsa-miR-4635 atcctTTCAAGAatggcat
 6
 UCUUGAAG m7a Disrupted 0.042000 no TS No effect
hsa-miR-4766-5p atcCTTTCAGgaatggcat
 0 UCUGAAAG m7b (m6c->m7b) no TS -0.006000 -0.120000
hsa-miR-488-3p atCCTTTCAAgaatggcat
 3
 UUGAAAGG m8a (m8a->m7b) -0.135000 -0.066000 0.010000
hsa-miR-526b-5p atccttTCAAGAatggcat
 1
 CUCUUGAG m6b Disrupted -0.093000 -0.096000 0.230000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.103909394->TTT ICGC_ssm_v2_17278 HX5T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3613-3p aatgttTTTTTTGgtatatataa
 0 ACAAAAAA m7b Disrupted 0.126000 0.094000 -0.750000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.103909545G>T COSN1125553 BN31T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-330-3p cctTGCTTTGttaatgcca
 1
 GCAAAGCA m7b (m7b->m6c) -0.209000 -0.056000 0.050000
hsa-miR-495 ccttgcTTTGTTaatgcca
 0 AAACAAAC m6b Disrupted 0.029000 no TS 0.020000
hsa-miR-5688 ccttgcTTTGTTAatgcca
 0 UAACAAAC m7a Disrupted 0.032000 no TS 0.507000
hsa-miR-7-1-3p ccttgcTTTGTTaatgcca
 0 CAACAAAU m6b Disrupted 0.030000 no TS 1.400000
hsa-miR-7-2-3p ccttgcTTTGTTaatgcca
 0 CAACAAAU m6b Disrupted 0.033000 no TS 0.350000
hsa-miR-330-3p cctTGCTTTGttaatgcca
 0 GCAAAGCA m7b (m7b->m6c) -0.209 -0.056 0.05
hsa-miR-495 ccttgcTTTGTTaatgcca
 0 AAACAAAC m6b Disrupted 0.029 no TS 0.02
hsa-miR-5688 ccttgcTTTGTTAatgcca
 0 UAACAAAC m7a Disrupted 0.032 no TS 0.507
hsa-miR-7-1-3p ccttgcTTTGTTaatgcca
 0 CAACAAAU m6b Disrupted 0.03 no TS 1.4
hsa-miR-7-2-3p ccttgcTTTGTTaatgcca
 0 CAACAAAU m6b Disrupted 0.033 no TS 0.35

Mutation Mutation ID Sample Name Cancer Type
chr11:g.103909562A>T COSN8729259 AOCS-001-1-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3120-3p tggTTGCTGTGtctcagcc
 0 CACAGCAA m8a Created no TS -0.067000 -0.750000
hsa-miR-3672 tggttgctgAGTCTCAgcc
 3
 AUGAGACU m7b (m7b->m6b) -0.096000 no TS 3.860000
hsa-miR-512-5p tggttGCTGAGTctcagcc
 7
 CACUCAGC m7b Disrupted -0.200000 no TS 2.560000
hsa-miR-873-3p tggttgctgAGTCTCagcc
 3
 GGAGACUG m6b Disrupted -0.096000 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.103909612C>T COSN15450165 AOCS-164-1-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-138-5p tcctACCAGCaaccaaact
 2
 AGCUGGUG m6b Disrupted -0.302000 -0.138000 0.110000
hsa-miR-409-5p tcctaccaGTAACCaaact
 0 AGGUUACC m6b Created no TS -0.146000 -0.010000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.103909666C>A COSN8863128 SNUH_G16_S1 [haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][acute_myeloid_leukaemia]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-30a-3p acattaagcCTGAAAGaac
 0 CUUUCAGU m7a (m7a->m6a) NA NA 0.080000
hsa-miR-30d-3p acattaagcCTGAAAGaac
 0 CUUUCAGU m7a (m7a->m6a) NA NA No effect
hsa-miR-30e-3p acattaagcCTGAAAGaac
 0 CUUUCAGU m7a (m7a->m6a) NA NA 0.180000
hsa-miR-3155a acattaAGCCTGaaagaac
 2
 CCAGGCUC m6b Disrupted -0.196000 no TS 0.090000
hsa-miR-3155b acattaAGCCTGaaagaac
 2
 CCAGGCUC m6b Disrupted -0.196000 no TS 0.140000
hsa-miR-484 acattaAGCCTGAaagaac
 2
 UCAGGCUC m7a Disrupted -0.189000 no TS 0.020000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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