SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001142770
Gene Symbol: PCDH15
Description: Homo sapiens protocadherin-related 15 (PCDH15), transcript variant A, mRNA.
Gene Location: chr10(-):55568451-56561051
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808698A>T COSN518598 TCGA-30-1857-01 [ovary][NS][carcinoma][serous_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-106a-5p caacacaGCACTTTga
 0 AAAAGUGC m7b Disrupted -0.156000 no TS 0.340000
hsa-miR-106b-5p caacacaGCACTTTga
 0 UAAAGUGC m7b Disrupted -0.156000 no TS 1.880000
hsa-miR-1276 caacacaGCTCTTTga
 0 UAAAGAGC m7b Created no TS -0.190000 -5.930000
hsa-miR-17-5p caacacaGCACTTTGa
 0 CAAAGUGC m8a Disrupted -0.156000 no TS 0.340000
hsa-miR-20a-5p caacacaGCACTTTga
 0 UAAAGUGC m7b Disrupted -0.156000 no TS 0.380000
hsa-miR-20b-5p caacacaGCACTTTGa
 0 CAAAGUGC m8a Disrupted -0.156000 no TS 0.930000
hsa-miR-302a-3p caacacAGCACTTtga
 0 UAAGUGCU m7b Disrupted -0.166000 no TS 0.850000
hsa-miR-302b-3p caacacAGCACTTtga
 0 UAAGUGCU m7b Disrupted -0.166000 no TS 0.170000
hsa-miR-302c-3p caacacAGCACTTtga
 0 UAAGUGCU m7b Disrupted -0.166000 no TS 0.030000
hsa-miR-302d-3p caacacAGCACTTtga
 0 UAAGUGCU m7b Disrupted -0.166000 no TS 0.020000
hsa-miR-302e caacacAGCACTTtga
 0 UAAGUGCU m7b Disrupted -0.138000 no TS 0.060000
hsa-miR-3609 caacacagCACTTTGa
 0 CAAAGUGA m7a Disrupted NA NA 1.940000
hsa-miR-372 caacacAGCACTTTga
 0 AAAGUGCU m8a Disrupted -0.129000 no TS 5.410000
hsa-miR-373-3p caacacAGCACTTtga
 0 GAAGUGCU m7b Disrupted -0.138000 no TS 0.210000
hsa-miR-3973 caacacagcACTTTGa
 0 ACAAAGUA m6b Disrupted -0.040000 no TS 5.230000
hsa-miR-512-3p caacaCAGCACTTtga
 0 AAGUGCUG m8a Disrupted -0.244000 no TS 6.100000
hsa-miR-519d caacacaGCACTTTGa
 0 CAAAGUGC m8a Disrupted -0.156000 no TS 12.690000
hsa-miR-520a-3p caacacAGCACTTTga
 0 AAAGUGCU m8a Disrupted -0.157000 no TS 0.880000
hsa-miR-520b caacacAGCACTTTga
 0 AAAGUGCU m8a Disrupted -0.138000 no TS 1.500000
hsa-miR-520c-3p caacacAGCACTTTga
 0 AAAGUGCU m8a Disrupted -0.138000 no TS 1.500000
hsa-miR-520d-3p caacacAGCACTTTga
 0 AAAGUGCU m8a Disrupted -0.157000 no TS 0.450000
hsa-miR-520e caacacAGCACTTTga
 0 AAAGUGCU m8a Disrupted -0.138000 no TS 0.880000
hsa-miR-520g caacacagCACTTTGa
 0 ACAAAGUG m7b Disrupted -0.196000 no TS 6.100000
hsa-miR-520h caacacagCACTTTGa
 0 ACAAAGUG m7b Disrupted -0.196000 no TS 6.100000
hsa-miR-526b-3p caacacaGCACTTTga
 0 GAAAGUGC m7b Disrupted -0.156000 no TS 1.550000
hsa-miR-583 caacacagCTCTTTGa
 0 CAAAGAGG m7a Created NA NA 2.440000
hsa-miR-93-5p caacacaGCACTTTGa
 0 CAAAGUGC m8a Disrupted -0.156000 no TS 1.560000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808702C>G cosmic_v64_1474863 Serous Ovarian
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1267 gttaCAACAGagcactttg
 0 CCUGUUGA m6b Created -0.096 -0.194 -1.96
hsa-miR-3194-3p gttacaaCAGAGCactttg
 0 AGCUCUGC m6b Created no TS -0.154 -6.71
hsa-miR-367-5p gttaCAACAGagcactttg
 0 ACUGUUGC m6b Created -0.359 -0.457 No effect
hsa-miR-512-3p gttacaacaCAGCACTTtg
 0 AAGUGCUG m8a (m8a->m7a) -0.244 no TS 4.39
hsa-miR-5691 gttacaaCAGAGCActttg
 0 UUGCUCUG m7b Created no TS -0.247 -11.08
hsa-miR-1267 gttaCAACAGagcactttg
 0 CCUGUUGA m6b Created -0.096000 -0.194000 -1.960000
hsa-miR-3194-3p gttacaaCAGAGCactttg
 0 AGCUCUGC m6b Created no TS -0.154000 -6.710000
hsa-miR-367-5p gttaCAACAGagcactttg
 0 ACUGUUGC m6b Created -0.359000 -0.457000 No effect
hsa-miR-512-3p gttacaacaCAGCACTTtg
 0 AAGUGCUG m8a (m8a->m7a) -0.244000 no TS 4.390000
hsa-miR-5691 gttacaaCAGAGCActttg
 0 UUGCUCUG m7b Created no TS -0.247000 -11.080000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808729C>A COSN2379152 TCGA-50-6590-01 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1273a agaaGTCGCCaggagcaaa
 0 GGGCGACA m6b Disrupted -0.256000 no TS 7.670000
hsa-miR-1915-5p agaagtcGCAAGGagcaaa
 0 ACCUUGCC m6b Created -0.158000 -0.323000 No effect
hsa-miR-221-5p agaagtcGCCAGGagcaaa
 0 ACCUGGCA m6b Disrupted -0.189000 no TS 5.530000
hsa-miR-4448 agaagtcgcAAGGAGCaaa
 0 GGCUCCUU m7b (m6b->m7b) -0.168000 -0.349000 -1.170000
hsa-miR-502-5p agaagtcGCAAGGAgcaaa
 0 AUCCUUGC m7b Created -0.421000 -0.601000 0.050000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808731G>A COSN519694 TCGA-AD-6889-01 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1273a aaagaaGTCGCCaggagca
 0 GGGCGACA m6b Disrupted -0.256000 no TS 7.670000
hsa-miR-221-5p aaagaagtcGCCAGGagca
 0 ACCUGGCA m6b Disrupted -0.189000 no TS 5.530000
hsa-miR-3164 aaagAAGTCACcaggagca
 0 UGUGACUU m7b Created no TS -0.148000 -0.900000
hsa-miR-4299 aaagaagTCACCAGgagca
 0 GCUGGUGA m7b Created no TS -0.184000 -0.520000
hsa-miR-4456 aaagaagtCACCAGGagca
 0 CCUGGUGG m7a Created -0.286000 -0.286000 -0.140000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808732C>A COSN1120165 HCC101T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1273a aaaagaaGTCGCCaggagc
 0 GGGCGACA m6b Disrupted -0.256000 no TS 7.670000
hsa-miR-138-1-3p aaaaGAAGTAGCcaggagc
 0 GCUACUUC m8a Created no TS -0.156000 -0.020000
hsa-miR-3682-5p aaaAGAAGTAGccaggagc
 0 CUACUUCU m8a Created no TS -0.140000 No effect
hsa-miR-4794 aaaagaagTAGCCAGgagc
 0 UCUGGCUA m7b Created -0.183000 -0.360000 -0.040000
hsa-miR-664-5p aaaagaagTAGCCAGgagc
 0 ACUGGCUA m7b Created -0.189000 -0.366000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808732C>T COSN5025473 TCGA-D3-A2JO-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1273a aaaagaaGTCGCCaggagc
 0 GGGCGACA m6b Disrupted -0.256000 no TS 7.670000
hsa-miR-196a-3p aaaagaaGTTGCCaggagc
 0 CGGCAACA m6b Created no TS -0.155000 -4.660000
hsa-miR-221-5p aaaagaagtTGCCAGGagc
 0 ACCUGGCA m7b (m6b->m7b) -0.189000 -0.445000 0.510000
hsa-miR-3128 aaaagaagTTGCCAGgagc
 0 UCUGGCAA m7b Created no TS -0.148000 -0.050000
hsa-miR-4720-5p aaaagaagtTGCCAGGagc
 0 CCUGGCAU m7a (m6a->m7a) NA NA -1.110000
hsa-miR-891b aaaagAAGTTGCcaggagc
 0 UGCAACUU m7b Created no TS -0.152000 -3.620000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808732C>A COSN5251949 HCC101 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1273a aaaagaaGTCGCCaggagc
 0 GGGCGACA m6b Disrupted -0.256000 no TS 7.670000
hsa-miR-138-1-3p aaaaGAAGTAGCcaggagc
 0 GCUACUUC m8a Created no TS -0.156000 -0.020000
hsa-miR-3682-5p aaaAGAAGTAGccaggagc
 0 CUACUUCU m8a Created no TS -0.140000 No effect
hsa-miR-4794 aaaagaagTAGCCAGgagc
 0 UCUGGCUA m7b Created -0.183000 -0.360000 -0.040000
hsa-miR-664-5p aaaagaagTAGCCAGgagc
 0 ACUGGCUA m7b Created -0.189000 -0.366000 No effect
hsa-miR-1273a aaaagaaGTCGCCaggagc
 0 GGGCGACA m6b Disrupted -0.256 no TS 7.67
hsa-miR-138-1-3p aaaaGAAGTAGCcaggagc
 0 GCUACUUC m8a Created no TS -0.156 -0.02
hsa-miR-3682-5p aaaAGAAGTAGccaggagc
 0 CUACUUCU m8a Created no TS -0.14 No effect
hsa-miR-4794 aaaagaagTAGCCAGgagc
 0 UCUGGCUA m7b Created -0.183 -0.36 -0.04
hsa-miR-664-5p aaaagaagTAGCCAGgagc
 0 ACUGGCUA m7b Created -0.189 -0.366 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808734G>A COSN1120166 HCC32T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1273a ccaaaagaaGTCGCCagga
 0 GGGCGACA m6b Disrupted -0.256000 no TS 7.670000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808734G>T COSN519695 TCGA-CM-4744-01 [large_intestine][caecum][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1273a ccaaaagaaGTCGCCagga
 0 GGGCGACA m6b Disrupted -0.256000 no TS 7.670000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808734G>A COSN5251950 HCC32 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1273a ccaaaagaaGTCGCCagga
 0 GGGCGACA m6b Disrupted -0.256000 no TS 7.670000
hsa-miR-1273a ccaaaagaaGTCGCCagga
 0 GGGCGACA m6b Disrupted -0.256 no TS 7.67

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808752G>T COSN1080042 TCGA-BS-A0TC-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-137 cagaAGCAATAAtgcaaac
 0 UUAUUGCU m8a Created no TS -0.320000 -2.230000
hsa-miR-137 cagaAGCAATAAtgcaaac
 0 UUAUUGCU m8a Created no TS -0.32 -2.23

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808757A>T COSN5263107 CHC469T [liver][NS][other][adenoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-103a-2-5p tatgacAGAAGCaagaatg
 0 AGCUUCUU m6b Disrupted -0.123000 no TS 0.060000
hsa-miR-3182 tatgACAGAAGCaagaatg
 0 GCUUCUGU m8a Disrupted -0.435000 -0.321000 No effect
hsa-miR-3977 tatgacaGAAGCAagaatg
 0 GUGCUUCA m6b Disrupted -0.193000 -0.093000 10.100000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808759G>T COSN1080041 TCGA-B5-A0JY-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-103a-2-5p cgtatgacAGAAGCaagaa
 0 AGCUUCUU m6b Disrupted -0.123000 no TS 0.010000
hsa-miR-3182 cgtatgACAGAAGCaagaa
 0 GCUUCUGU m8a Disrupted -0.435000 -0.321000 No effect
hsa-miR-3977 cgtatgacaGAAGCAagaa
 0 GUGCUUCA m6b Disrupted -0.193000 -0.093000 10.100000
hsa-miR-103a-2-5p cgtatgacAGAAGCaagaa
 0 AGCUUCUU m6b Disrupted -0.123 no TS 0.01
hsa-miR-3182 cgtatgACAGAAGCaagaa
 0 GCUUCUGU m8a Disrupted -0.435 -0.321 No effect
hsa-miR-3977 cgtatgacaGAAGCAagaa
 0 GUGCUUCA m6b Disrupted -0.193 -0.093 10.1

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808763G>A cosmic_v64_1673891 Melanoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-let-7d-3p ccagCGTATAacagaagca
 0 CUAUACGA m6b Created no TS -0.162 -8.01
hsa-let-7e-3p ccagCGTATAacagaagca
 0 CUAUACGG m6b Created no TS -0.16 -8.25
hsa-miR-4652-3p ccagcgtatAACAGAAgca
 0 GUUCUGUU m7b (m6b->m7b) -0.09 -0.172 -0.26
hsa-miR-485-3p ccagcGTATGACagaagca
 0 GUCAUACA m7a Disrupted NA NA 6.71

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808783G>A COSN1080040 TCGA-BS-A0UF-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3189-5p gtccATGGGGCtatcaggt
 0 UGCCCCAU m7b Disrupted -0.210000 no TS 8.640000
hsa-miR-3651 gtccatgGGGCTATcaggt
 0 CAUAGCCC m7b Disrupted -0.203000 no TS 10.130000
hsa-miR-4323 gtccaTGGGGCTatcaggt
 0 CAGCCCCA m7b Disrupted -0.492000 no TS 9.740000
hsa-miR-5588-3p gtccaTGGGACTatcaggt
 0 AAGUCCCA m7b Created no TS -0.420000 -0.080000
hsa-miR-3189-5p gtccATGGGGCtatcaggt
 0 UGCCCCAU m7b Disrupted -0.21 no TS 8.64
hsa-miR-3651 gtccatgGGGCTATcaggt
 0 CAUAGCCC m7b Disrupted -0.203 no TS 10.13
hsa-miR-4323 gtccaTGGGGCTatcaggt
 0 CAGCCCCA m7b Disrupted -0.492 no TS 9.74
hsa-miR-5588-3p gtccaTGGGACTatcaggt
 0 AAGUCCCA m7b Created no TS -0.42 -0.08

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808798C>T cosmic_v64_1474871 Serous Ovarian
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4494 aaagtCAGTCTGGaggtcc
 0 CCAGACUG m8a Disrupted -0.375 -0.213 0.17
hsa-miR-4499 aaagTCAGTCTggaggtcc
 0 AAGACUGA m7b Disrupted -0.077 no TS 1.3
hsa-miR-4513 aaaGTCAGTCTggaggtcc
 0 AGACUGAC m8a Disrupted -0.193 no TS 1.33
hsa-miR-4494 aaagtCAGTCTGGaggtcc
 0 CCAGACUG m8a Disrupted -0.375000 -0.213000 0.170000
hsa-miR-4499 aaagTCAGTCTggaggtcc
 0 AAGACUGA m7b Disrupted -0.077000 no TS 1.300000
hsa-miR-4513 aaaGTCAGTCTggaggtcc
 0 AGACUGAC m8a Disrupted -0.193000 no TS 1.330000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808800G>A COSN5025474 TCGA-EE-A3J8-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4494 cgaaagtCAGTCTGGaggt
 0 CCAGACUG m8a Disrupted -0.375000 -0.213000 0.240000
hsa-miR-4499 cgaaagTCAGTCTggaggt
 0 AAGACUGA m7b Disrupted -0.077000 no TS 5.870000
hsa-miR-4513 cgaaaGTCAGTCTggaggt
 0 AGACUGAC m8a Disrupted -0.193000 no TS 7.770000
hsa-miR-488-5p cgaaagtcaATCTGGaggt
 0 CCCAGAUA m6b Created no TS -0.094000 -0.020000


Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808808G>A COSN8309302 TCGA-AN-A046-01 [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808853G>A COSN5025475 TCGA-EE-A2MD-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1228-3p ggAGGTGTGAaaagtgagg
 0 UCACACCU m8a (m7b->m8a) -0.136000 -0.312000 0.110000
hsa-miR-3692-3p ggaggTGTGGAAagtgagg
 0 GUUCCACA m7b Disrupted -0.281000 -0.077000 3.510000
hsa-miR-377-3p ggagGTGTGAaaagtgagg
 0 AUCACACA m6b Created no TS -0.098000 -4.190000
hsa-miR-5003-3p ggaggtgtGAAAAGTgagg
 0 UACUUUUC m7b Created no TS -0.031000 0.010000
hsa-miR-5096 ggaggtGTGAAAagtgagg
 0 GUUUCACC m6b Created no TS 0.001000 -0.420000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808870C>T COSN1080039 TCGA-AP-A0LM-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-320a aatCAGCTTTggtggaagg
 0 AAAAGCUG m7b (m6c->m7b) no TS -0.091000 -6.130000
hsa-miR-320b aatCAGCTTTggtggaagg
 0 AAAAGCUG m7b (m6c->m7b) no TS -0.091000 -6.130000
hsa-miR-320c aatCAGCTTTggtggaagg
 0 AAAAGCUG m7b (m6c->m7b) no TS -0.091000 -6.930000
hsa-miR-320d aatCAGCTTTggtggaagg
 0 AAAAGCUG m7b (m6c->m7b) no TS -0.091000 -3.330000
hsa-miR-4429 aatCAGCTTTggtggaagg
 0 AAAAGCUG m7b (m6c->m7b) no TS -0.100000 -6.740000
hsa-miR-320a aatCAGCTTTggtggaagg
 0 AAAAGCUG m7b (m6c->m7b) no TS -0.091 -6.13
hsa-miR-320b aatCAGCTTTggtggaagg
 0 AAAAGCUG m7b (m6c->m7b) no TS -0.091 -6.13
hsa-miR-320c aatCAGCTTTggtggaagg
 0 AAAAGCUG m7b (m6c->m7b) no TS -0.091 -6.93
hsa-miR-320d aatCAGCTTTggtggaagg
 0 AAAAGCUG m7b (m6c->m7b) no TS -0.091 -3.33
hsa-miR-4429 aatCAGCTTTggtggaagg
 0 AAAAGCUG m7b (m6c->m7b) no TS -0.1 -6.74

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808876C>T COSN5793614 OSCC-GB_00050111 [upper_aerodigestive_tract][mouth][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4778-5p gtgCAGAATTagcttcggt
 0 AAUUCUGU m7a (m6b->m7a) -0.044000 -0.044000 -0.030000
hsa-miR-5571-5p gtgcAGAATTagcttcggt
 0 CAAUUCUC m6b Created no TS 0.034000 -2.520000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808904G>C COSN4710408 TCGA-BS-A0UA-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-190a gaagctcaACATATCcctg
 0 UGAUAUGU m7b Created no TS -0.082000 -2.760000
hsa-miR-190b gaagctcaACATATCcctg
 0 UGAUAUGU m7b Created no TS -0.091000 -2.770000
hsa-miR-3201 gaagctcaaCATATCCCtg
 0 GGGAUAUG m8a (m7a->m8a) no TS -0.137000 -2.670000
hsa-miR-4781-3p gaagctCAACATatccctg
 0 AAUGUUGG m6b Created no TS -0.022000 -0.160000
hsa-miR-4791 gaagctcaaCATATCCctg
 0 UGGAUAUG m7b (m6b->m7b) no TS -0.155000 -1.970000
hsa-miR-526b-5p gaagCTCAAGAtatccctg
 0 CUCUUGAG m7b Disrupted -0.124000 no TS 0.830000
hsa-miR-190a gaagctcaACATATCcctg
 0 UGAUAUGU m7b Created no TS -0.082000 -2.760000
hsa-miR-190b gaagctcaACATATCcctg
 0 UGAUAUGU m7b Created no TS -0.091000 -2.770000
hsa-miR-3201 gaagctcaaCATATCCCtg
 0 GGGAUAUG m8a (m7a->m8a) no TS -0.137000 -2.670000
hsa-miR-4781-3p gaagctCAACATatccctg
 0 AAUGUUGG m6b Created no TS -0.022000 -0.160000
hsa-miR-4791 gaagctcaaCATATCCctg
 0 UGGAUAUG m7b (m6b->m7b) no TS -0.155000 -1.970000
hsa-miR-526b-5p gaagCTCAAGAtatccctg
 0 CUCUUGAG m7b Disrupted -0.124000 no TS 0.830000
hsa-miR-190a gaagctcaACATATCcctg
 0 UGAUAUGU m7b Created no TS -0.082 -2.76
hsa-miR-190b gaagctcaACATATCcctg
 0 UGAUAUGU m7b Created no TS -0.091 -2.77
hsa-miR-3201 gaagctcaaCATATCCCtg
 0 GGGAUAUG m8a (m7a->m8a) no TS -0.137 -2.67
hsa-miR-4781-3p gaagctCAACATatccctg
 0 AAUGUUGG m6b Created no TS -0.022 -0.16
hsa-miR-4791 gaagctcaaCATATCCctg
 0 UGGAUAUG m7b (m6b->m7b) no TS -0.155 -1.97
hsa-miR-526b-5p gaagCTCAAGAtatccctg
 0 CUCUUGAG m7b Disrupted -0.124 no TS 0.83

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808913G>A COSN8407886 ESCC-184T [oesophagus][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2909 acagaCCCTAAagctcaag
 0 GUUAGGGC m6b Created no TS -0.101000 -3.270000
hsa-miR-3127-5p acagaCCCTGAagctcaag
 0 AUCAGGGC m6b Disrupted -0.404000 -0.289000 0.040000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808944A>G COSN1080038 TCGA-B5-A0JY-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4436b-5p agaAAGTGGACcagcccct
 0 GUCCACUU m8a Disrupted -0.114000 no TS No effect
hsa-miR-4436b-5p agaAAGTGGACcagcccct
 0 GUCCACUU m8a Disrupted -0.114 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53808952G>T COSN4710409 TCGA-BS-A0UA-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4659a-3p gaagaAGAAGAAAgtggac
 0 UUUCUUCU m8a Disrupted -0.473000 -0.395000 0.030000
hsa-miR-4659b-3p gaagaAGAAGAAAgtggac
 0 UUUCUUCU m8a Disrupted -0.473000 -0.395000 0.050000
hsa-miR-4778-3p gaaGAAGAAGAaagtggac
 0 UCUUCUUC m8a Disrupted -1.425000 -1.224000 0.870000
hsa-miR-4659a-3p gaagaAGAAGAAAgtggac
 0 UUUCUUCU m8a Disrupted -0.473000 -0.395000 0.030000
hsa-miR-4659b-3p gaagaAGAAGAAAgtggac
 0 UUUCUUCU m8a Disrupted -0.473000 -0.395000 0.050000
hsa-miR-4778-3p gaaGAAGAAGAaagtggac
 0 UCUUCUUC m8a Disrupted -1.425000 -1.224000 0.870000
hsa-miR-4659a-3p gaagaAGAAGAAAgtggac
 0 UUUCUUCU m8a Disrupted -0.473 -0.395 0.03
hsa-miR-4659b-3p gaagaAGAAGAAAgtggac
 0 UUUCUUCU m8a Disrupted -0.473 -0.395 0.05
hsa-miR-4778-3p gaaGAAGAAGAaagtggac
 0 UCUUCUUC m8a Disrupted -1.425 -1.224 0.87

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809009C>A COSN2378374 TCGA-34-5231-01 [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4268 aaaGAGGAGCCacaagaag
 0 GGCUCCUC m8a Disrupted -0.390000 -0.161000 0.280000
hsa-miR-4279 aaaGAGGAGAcacaagaag
 0 CUCUCCUC m7b (m6c->m7b) -0.176000 -0.359000 -0.400000
hsa-miR-4448 aaagAGGAGCCacaagaag
 0 GGCUCCUU m7a Disrupted -0.168000 -0.168000 3.460000
hsa-miR-4474-3p aaagaggAGCCACAAgaag
 0 UUGUGGCU m8a Disrupted -0.302000 no TS 10.450000
hsa-miR-4711-3p aaagaggAGACACaagaag
 0 CGUGUCUU m6b Created no TS -0.110000 -1.950000
hsa-miR-581 aaagaggagACACAAGAag
 0 UCUUGUGU m8a (m7a->m8a) -0.088000 -0.253000 -1.460000
hsa-miR-599 aaagaggaGACACAAgaag
 0 GUUGUGUC m7b Created no TS -0.136000 -3.040000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809013G>T COSN4710410 TCGA-BS-A0UA-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-130b-5p tagGAAAGAGgagccacaa
 0 ACUCUUUC m7b (m7b->m6c) -0.053000 no TS 1.230000
hsa-miR-4268 taggaaaGAGGAGCCacaa
 0 GGCUCCUC m8a Disrupted -0.390000 -0.161000 0.280000
hsa-miR-4284 taggaaagaTGAGCCacaa
 0 GGGCUCAC m6b Created no TS -0.129000 -9.210000
hsa-miR-4448 taggaaagAGGAGCCacaa
 0 GGCUCCUU m7a Disrupted -0.168000 -0.168000 3.460000
hsa-miR-130b-5p tagGAAAGAGgagccacaa
 0 ACUCUUUC m7b (m7b->m6c) -0.053000 no TS 1.230000
hsa-miR-4268 taggaaaGAGGAGCCacaa
 0 GGCUCCUC m8a Disrupted -0.390000 -0.161000 0.280000
hsa-miR-4284 taggaaagaTGAGCCacaa
 0 GGGCUCAC m6b Created no TS -0.129000 -9.210000
hsa-miR-4448 taggaaagAGGAGCCacaa
 0 GGCUCCUU m7a Disrupted -0.168000 -0.168000 3.460000
hsa-miR-130b-5p tagGAAAGAGgagccacaa
 0 ACUCUUUC m7b (m7b->m6c) -0.053 no TS 1.23
hsa-miR-4268 taggaaaGAGGAGCCacaa
 0 GGCUCCUC m8a Disrupted -0.39 -0.161 0.28
hsa-miR-4284 taggaaagaTGAGCCacaa
 0 GGGCUCAC m6b Created no TS -0.129 -9.21
hsa-miR-4448 taggaaagAGGAGCCacaa
 0 GGCUCCUU m7a Disrupted -0.168 -0.168 3.46

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809019G>A COSN8355726 TCGA-EE-A2M6-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-130b-5p caagggtagGAAAGAGgag
 0 ACUCUUUC m7b (m7b->m6b) -0.053000 no TS 1.280000
hsa-miR-155-3p caaggGTAGGAaagaggag
 0 CUCCUACA m6b Disrupted -0.099000 no TS 5.600000
hsa-miR-3124-3p caagggtAGGAAAGaggag
 0 ACUUUCCU m7b Disrupted -0.167000 no TS 0.080000
hsa-miR-3685 caaggGTAGGAAAgaggag
 0 UUUCCUAC m8a Disrupted -0.169000 no TS 5.540000
hsa-miR-384 caagggTAGGAAagaggag
 0 AUUCCUAG m6b Disrupted -0.025000 no TS 1.420000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809062G>T cosmic_v64_1651648 Rectum
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-25-3p tgctTGCAATaagaaggcc
 0 CAUUGCAC m6b Created no TS -0.033 -0.01
hsa-miR-32-5p tgctTGCAATAagaaggcc
 0 UAUUGCAC m7a Created no TS -0.04 -1.82
hsa-miR-363-3p tgctTGCAATaagaaggcc
 0 AAUUGCAC m6b Created no TS -0.037 -3.88
hsa-miR-367-3p tgctTGCAATaagaaggcc
 0 AAUUGCAC m6b Created no TS -0.054 -2.13
hsa-miR-4659a-3p tgcttgcaAGAAGAAggcc
 0 UUUCUUCU m7b Disrupted -0.473 -0.473 -0.01
hsa-miR-4659b-3p tgcttgcaAGAAGAAggcc
 0 UUUCUUCU m7b Disrupted -0.473 -0.473 No effect
hsa-miR-4778-3p tgcttgcAAGAAGAaggcc
 0 UCUUCUUC m7a Disrupted -1.425 -1.325 No effect
hsa-miR-578 tgcttgCAAGAAGaaggcc
 0 CUUCUUGU m7a Disrupted -0.026 -0.026 0.03
hsa-miR-92a-3p tgctTGCAATAagaaggcc
 0 UAUUGCAC m7a Created no TS -0.026 No effect
hsa-miR-92b-3p tgctTGCAATAagaaggcc
 0 UAUUGCAC m7a Created no TS -0.033 -0.05
hsa-miR-25-3p tgctTGCAATaagaaggcc
 0 CAUUGCAC m6b Created no TS -0.033000 -0.010000
hsa-miR-32-5p tgctTGCAATAagaaggcc
 0 UAUUGCAC m7a Created no TS -0.040000 -1.820000
hsa-miR-363-3p tgctTGCAATaagaaggcc
 0 AAUUGCAC m6b Created no TS -0.037000 -3.880000
hsa-miR-367-3p tgctTGCAATaagaaggcc
 0 AAUUGCAC m6b Created no TS -0.054000 -2.130000
hsa-miR-4659a-3p tgcttgcaAGAAGAAggcc
 0 UUUCUUCU m7b Disrupted -0.473000 -0.473000 -0.010000
hsa-miR-4659b-3p tgcttgcaAGAAGAAggcc
 0 UUUCUUCU m7b Disrupted -0.473000 -0.473000 No effect
hsa-miR-4778-3p tgcttgcAAGAAGAaggcc
 0 UCUUCUUC m7a Disrupted -1.425000 -1.325000 No effect
hsa-miR-578 tgcttgCAAGAAGaaggcc
 0 CUUCUUGU m7a Disrupted -0.026000 -0.026000 0.030000
hsa-miR-92a-3p tgctTGCAATAagaaggcc
 0 UAUUGCAC m7a Created no TS -0.026000 No effect
hsa-miR-92b-3p tgctTGCAATAagaaggcc
 0 UAUUGCAC m7a Created no TS -0.033000 -0.050000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809077A>G cosmic_v64_1651109 Colorectal
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3140-3p caaggAAAAGCattgtgct
 0 AGCUUUUG m6b Created -0.006 -0.007 -0.17
hsa-miR-33a-3p caaggaaAAACATTGtgct
 0 CAAUGUUU m8a Disrupted -0.007 no TS 0.1
hsa-miR-4307 caaggaAAAACATTgtgct
 0 AAUGUUUU m8a Disrupted 0 no TS 0.19
hsa-miR-3140-3p caaggAAAAGCattgtgct
 0 AGCUUUUG m6b Created -0.006000 -0.007000 -0.170000
hsa-miR-33a-3p caaggaaAAACATTGtgct
 0 CAAUGUUU m8a Disrupted -0.007000 no TS 0.100000
hsa-miR-4307 caaggaAAAACATTgtgct
 0 AAUGUUUU m8a Disrupted -0.000000 no TS 0.190000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809079A>T COSN8860811 TCGA-HE-7129-01 [kidney][NS][carcinoma][papillary_renal_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-33a-3p agcaaggaaAAACATTGtg
 0 CAAUGUUU m8a (m8a->m7a) -0.007000 no TS -0.390000
hsa-miR-4307 agcaaggaAAAACATTgtg
 0 AAUGUUUU m8a Disrupted -0.000000 no TS 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809082G>A COSN5025476 TCGA-D3-A3C1-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1915-5p aaaaGCAAGGaaaaacatt
 0 ACCUUGCC m6b Disrupted -0.158000 no TS -0.030000
hsa-miR-502-5p aaaaGCAAGGAaaaacatt
 0 AUCCUUGC m7b Disrupted -0.421000 -0.048000 1.390000
hsa-miR-578 aaaagCAAGAAaaaacatt
 0 CUUCUUGU m6b Created -0.026000 -0.072000 -0.070000
hsa-miR-1915-5p aaaaGCAAGGaaaaacatt
 0 ACCUUGCC m6b Disrupted -0.158000 no TS -0.030000
hsa-miR-502-5p aaaaGCAAGGAaaaacatt
 0 AUCCUUGC m7b Disrupted -0.421000 -0.048000 1.390000
hsa-miR-578 aaaagCAAGAAaaaacatt
 0 CUUCUUGU m6b Created -0.026000 -0.072000 -0.070000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809086C>T COSN409397 TCGA-BP-4161-01 [kidney][NS][carcinoma][clear_cell_renal_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1915-5p gagaaaaaGCAAGGaaaaa
 0 ACCUUGCC m6b Disrupted -0.158000 no TS 0.550000
hsa-miR-3140-3p gagaAAAAGCaaggaaaaa
 0 AGCUUUUG m6b Disrupted -0.006000 no TS 0.130000
hsa-miR-5003-3p gagaAAAAGTAaggaaaaa
 0 UACUUUUC m7a Created no TS 0.043000 0.010000
hsa-miR-502-5p gagaaaaaGCAAGGAaaaa
 0 AUCCUUGC m7b Disrupted -0.421000 -0.048000 0.140000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809095G>A COSN5025478 TCGA-GN-A26C-01 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1237 agtCAGAAGGAgaaaaagc
 0 UCCUUCUG m8a Disrupted -0.268000 no TS 7.380000
hsa-miR-4279 agtcagaAGGAGAaaaagc
 0 CUCUCCUC m6b Disrupted -0.176000 -0.092000 0.400000
hsa-miR-4659a-3p agtcagaAGAAGAAAaagc
 0 UUUCUUCU m8a Created -0.473000 -0.659000 -0.090000
hsa-miR-4659b-3p agtcagaAGAAGAAAaagc
 0 UUUCUUCU m8a Created -0.473000 -0.659000 -0.110000
hsa-miR-4778-3p agtcaGAAGAAGAaaaagc
 0 UCUUCUUC m8a Created -1.425000 -1.613000 -0.010000
hsa-miR-629-3p agtcagaaGGAGAAaaagc
 0 GUUCUCCC m6b Disrupted -0.067000 no TS 0.150000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809101C>T COSN504360 8014187 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1237 ccacagagtCAGAAGGAga
 0 UCCUUCUG m8a (m8a->m7a) -0.268000 -0.074000 1.670000
hsa-miR-345-5p ccacaGAGTCAGaaggaga
 0 GCUGACUC m7b Disrupted -0.656000 -0.326000 0.030000
hsa-miR-3664-5p ccACAGAGTTagaaggaga
 0 AACUCUGU m8a (m7b->m8a) -0.091000 -0.118000 -0.760000
hsa-miR-4256 ccacagaGTCAGAaggaga
 0 AUCUGACC m6b Disrupted -0.084000 no TS 8.020000
hsa-miR-4522 ccaCAGAGTCAgaaggaga
 0 UGACUCUG m8a Disrupted -0.292000 no TS 1.580000
hsa-miR-4714-5p ccaCAGAGTTagaaggaga
 0 AACUCUGA m7a (m6b->m7a) NA NA -0.460000
hsa-miR-618 ccacAGAGTTagaaggaga
 0 AAACUCUA m6b Created no TS -0.062000 -2.510000
hsa-miR-1237 ccacagagtCAGAAGGAga
 0 UCCUUCUG m8a (m8a->m7a) -0.268 -0.074 1.67
hsa-miR-345-5p ccacaGAGTCAGaaggaga
 0 GCUGACUC m7b Disrupted -0.656 -0.326 0.03
hsa-miR-3664-5p ccACAGAGTTagaaggaga
 0 AACUCUGU m8a (m7b->m8a) -0.091 -0.118 -0.76
hsa-miR-4256 ccacagaGTCAGAaggaga
 0 AUCUGACC m6b Disrupted -0.084 no TS 8.02
hsa-miR-4522 ccaCAGAGTCAgaaggaga
 0 UGACUCUG m8a Disrupted -0.292 no TS 1.58
hsa-miR-4714-5p ccaCAGAGTTagaaggaga
 0 AACUCUGA m7a (m6b->m7a) NA NA -0.46
hsa-miR-618 ccacAGAGTTagaaggaga
 0 AAACUCUA m6b Created no TS -0.062 -2.51

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809107C>A COSN525994 TCGA-97-7938-01 [lung][right_upper_lobe][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3664-5p cggaatccACAGAGTcaga
 0 AACUCUGU m7b Disrupted -0.091000 no TS 1.010000
hsa-miR-3691-5p cggaATCCACagagtcaga
 0 AGUGGAUG m6b Disrupted -0.081000 no TS 7.920000
hsa-miR-4522 cggaatccaCAGAGTCAga
 0 UGACUCUG m8a (m8a->m7a) -0.292000 -0.092000 1.130000
hsa-miR-4752 cggaATCCACAgagtcaga
 0 UUGUGGAU m7b Disrupted -0.135000 no TS 0.930000
hsa-miR-5004-3p cggAATCCAAagagtcaga
 0 CUUGGAUU m7b (m6c->m7b) no TS -0.098000 -12.970000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809142G>T COSN1080037 TCGA-AP-A051-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4279 ggagGAGGAGAGttccacc
 0 CUCUCCUC m8a Disrupted -0.176000 -0.084000 0.120000
hsa-miR-4680-5p ggaggaggAGAGTTCcacc
 0 AGAACUCU m7b Disrupted -0.126000 -0.089000 2.280000
hsa-miR-4279 ggagGAGGAGAGttccacc
 0 CUCUCCUC m8a Disrupted -0.176 -0.084 0.12
hsa-miR-4680-5p ggaggaggAGAGTTCcacc
 0 AGAACUCU m7b Disrupted -0.126 -0.089 2.28

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809156T>A COSN2378373 TCGA-43-2578-01 [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-194-3p gagacaCCCACTGaggagg
 0 CCAGUGGG m7b Created no TS -0.345000 -5.320000
hsa-miR-4257 gagacacCCTCTGaggagg
 0 CCAGAGGU m6b Disrupted -0.096000 no TS 2.580000
hsa-miR-4330 gagacacccTCTGAGGagg
 0 CCUCAGAU m7a (m7a->m6a) -0.206000 -0.206000 2.760000
hsa-miR-5693 gagacacCCACTGaggagg
 0 GCAGUGGC m6b Created no TS -0.086000 -0.250000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809157C>T COSN2378372 TCGA-60-2698-01 [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3154 agagacaCCTTCTGaggag
 0 CAGAAGGG m7a Created NA NA -0.300000
hsa-miR-4257 agagacacCCTCTGaggag
 0 CCAGAGGU m6b Disrupted -0.096000 no TS 0.140000
hsa-miR-3154 agagacaCCTTCTGaggag
 0 CAGAAGGG m7a Created NA NA -0.300000
hsa-miR-4257 agagacacCCTCTGaggag
 0 CCAGAGGU m6b Disrupted -0.096000 no TS 0.140000
hsa-miR-3154 agagacaCCTTCTGaggag
 0 CAGAAGGG m7a Created NA NA -0.300000
hsa-miR-4257 agagacacCCTCTGaggag
 0 CCAGAGGU m6b Disrupted -0.096000 no TS 0.140000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809167C>T COSN8309303 TCGA-AC-A2B8-01 [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-146a-3p aatctgagTCAGAGacacc
 0 CCUCUGAA m6b Disrupted -0.068000 no TS 9.130000
hsa-miR-301a-5p aatctgaGTCAGAGacacc
 0 GCUCUGAC m7b Disrupted -0.284000 no TS 0.030000
hsa-miR-345-5p aatctGAGTCAGagacacc
 0 GCUGACUC m7b Disrupted -0.656000 -0.330000 0.010000
hsa-miR-593-3p aatctgagtCAGAGACAcc
 0 UGUCUCUG m8a (m8a->m7a) -0.353000 -0.162000 -0.020000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809177G>A COSN8355727 TCGA-FW-A3R5-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-10b-3p acagaagagGAATCTGagt
 0 ACAGAUUC m7b (m7b->m6b) -0.190000 -0.022000 0.740000
hsa-miR-1236 acaGAAGAGGaatctgagt
 0 CCUCUUCC m7a (m7a->m6b) -0.369000 -0.448000 -0.010000
hsa-miR-145-3p acagaagAGGAATCtgagt
 0 GGAUUCCU m7b Disrupted -0.638000 -0.528000 -0.010000
hsa-miR-4753-3p acagAAGAGAAatctgagt
 0 UUCUCUUU m7a Created no TS -0.038000 -0.030000
hsa-miR-4768-5p acagaAGAGAAatctgagt
 0 AUUCUCUC m6b Created no TS -0.012000 -0.210000
hsa-miR-877-3p acaGAAGAGGAatctgagt
 0 UCCUCUUC m8a Disrupted -0.692000 -0.380000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809219G>A COSN14654518 TCGA-BF-A1PZ-01 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1183 gaaTACAGTGaagaagagt
 0 CACUGUAG m7a (m7a->m6b) no TS -0.087000 -0.010000
hsa-miR-1208 gaatACAGTGAagaagagt
 0 UCACUGUU m7a Disrupted -0.107000 no TS 0.010000
hsa-miR-181b-3p gaataCAGTGAagaagagt
 0 CUCACUGA m6b Disrupted -0.230000 -0.142000 0.180000
hsa-miR-412 gaatacaGTGAAGaagagt
 0 ACUUCACC m6b Disrupted -0.367000 -0.279000 No effect
hsa-miR-4420 gaataCAGTGAagaagagt
 0 GUCACUGA m6b Disrupted -0.231000 -0.133000 0.090000
hsa-miR-4693-5p gaatACAGTAaagaagagt
 0 AUACUGUG m6b Created no TS -0.092000 No effect
hsa-miR-4778-3p gaatacagtGAAGAAGAgt
 0 UCUUCUUC m8a (m8a->m7a) -1.425000 -1.234000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809238C>G COSN2379150 TCGA-50-5045-01 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2114-5p atcctccAGGGACTAtact
 0 UAGUCCCU m8a Created no TS -0.349000 -0.110000
hsa-miR-3135b atcCTCCAGCgactatact
 0 GGCUGGAG m7b (m7b->m6c) -0.166000 no TS 0.520000
hsa-miR-4254 atcCTCCAGGgactatact
 0 GCCUGGAG m7b (m6c->m7b) no TS -0.214000 -3.890000
hsa-miR-4292 atcctCCAGGGactatact
 0 CCCCUGGG m6b Created no TS -0.155000 No effect
hsa-miR-4308 atccTCCAGGGActatact
 0 UCCCUGGA m8a Created no TS -0.382000 -5.430000
hsa-miR-5588-3p atcctccaGGGACTatact
 0 AAGUCCCA m6b Created no TS -0.157000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809249G>A COSN5025479 TCGA-D3-A5GN-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-145-3p tcagaggAGGAATCCtcca
 0 GGAUUCCU m8a Disrupted -0.638000 -0.544000 0.010000
hsa-miR-3167 tcagaggaGAAATCCTcca
 0 AGGAUUUC m8a Created no TS -0.104000 0.050000
hsa-miR-4279 tcaGAGGAGAaatcctcca
 0 CUCUCCUC m7b (m6c->m7b) -0.176000 -0.541000 No effect
hsa-miR-4691-5p tcagaGGAGGAatcctcca
 0 GUCCUCCA m6b Disrupted -0.268000 -0.136000 No effect
hsa-miR-5193 tcaGAGGAGGAatcctcca
 0 UCCUCCUC m8a Disrupted -1.637000 -1.237000 No effect
hsa-miR-629-3p tcagaGGAGAAatcctcca
 0 GUUCUCCC m6b Created -0.067000 -0.137000 No effect
hsa-miR-660-3p tcagAGGAGGaatcctcca
 0 ACCUCCUG m6b Disrupted -0.436000 -0.308000 No effect
hsa-miR-876-5p tcagaggaGAAATCCtcca
 0 UGGAUUUC m7b Created no TS -0.132000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809255G>A COSN525993 TCGA-55-6972-01 [lung][right_upper_lobe][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-146a-3p gtagaaTCAGAGGaggaat
 0 CCUCUGAA m7a Disrupted -0.068000 -0.068000 0.110000
hsa-miR-29a-5p gtagAATCAGaggaggaat
 0 ACUGAUUU m6b Disrupted -0.088000 -0.057000 No effect
hsa-miR-3920 gtagAATCAGaggaggaat
 0 ACUGAUUA m6b Disrupted -0.135000 -0.095000 No effect
hsa-miR-5193 gtagaatcaGAGGAGGAat
 0 UCCUCCUC m8a (m8a->m7a) -1.637000 -1.377000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809283G>T COSN4710411 TCGA-BS-A0UA-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2115-5p ggaccaagaGGAAGCaaca
 0 AGCUUCCA m6b Disrupted -0.144000 no TS No effect
hsa-miR-3977 ggaccaagaTGAAGCAaca
 0 GUGCUUCA m7b (m6b->m7b) -0.193000 -0.375000 -0.270000
hsa-miR-452-3p ggaccaAGATGAagcaaca
 0 CUCAUCUG m6b Created no TS -0.044000 -2.200000
hsa-miR-516a-3p ggaccaagAGGAAGCAaca
 0 UGCUUCCU m8a Disrupted -0.334000 no TS No effect
hsa-miR-516b-3p ggaccaagAGGAAGCAaca
 0 UGCUUCCU m8a Disrupted -0.334000 no TS No effect
hsa-miR-877-3p ggaccAAGAGGAagcaaca
 0 UCCUCUUC m7a Disrupted -0.692000 -0.606000 No effect
hsa-miR-2115-5p ggaccaagaGGAAGCaaca
 0 AGCUUCCA m6b Disrupted -0.144000 no TS No effect
hsa-miR-3977 ggaccaagaTGAAGCAaca
 0 GUGCUUCA m7b (m6b->m7b) -0.193000 -0.375000 -0.270000
hsa-miR-452-3p ggaccaAGATGAagcaaca
 0 CUCAUCUG m6b Created no TS -0.044000 -2.200000
hsa-miR-516a-3p ggaccaagAGGAAGCAaca
 0 UGCUUCCU m8a Disrupted -0.334000 no TS No effect
hsa-miR-516b-3p ggaccaagAGGAAGCAaca
 0 UGCUUCCU m8a Disrupted -0.334000 no TS No effect
hsa-miR-877-3p ggaccAAGAGGAagcaaca
 0 UCCUCUUC m7a Disrupted -0.692000 -0.606000 No effect
hsa-miR-2115-5p ggaccaagaGGAAGCaaca
 0 AGCUUCCA m6b Disrupted -0.144 no TS No effect
hsa-miR-3977 ggaccaagaTGAAGCAaca
 0 GUGCUUCA m7b (m6b->m7b) -0.193 -0.375 -0.27
hsa-miR-452-3p ggaccaAGATGAagcaaca
 0 CUCAUCUG m6b Created no TS -0.044 -2.2
hsa-miR-516a-3p ggaccaagAGGAAGCAaca
 0 UGCUUCCU m8a Disrupted -0.334 no TS No effect
hsa-miR-516b-3p ggaccaagAGGAAGCAaca
 0 UGCUUCCU m8a Disrupted -0.334 no TS No effect
hsa-miR-877-3p ggaccAAGAGGAagcaaca
 0 UCCUCUUC m7a Disrupted -0.692 -0.606 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809294C>G COSN2379149 TCGA-50-6590-01 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-128 aaactCACTGTGgaccaag
 0 UCACAGUG m7b Created no TS -0.177000 -1.320000
hsa-miR-198 aaactcacTCTGGACCaag
 0 GGUCCAGA m8a Disrupted -0.198000 no TS 0.020000
hsa-miR-3681-3p aaactCACTGTGgaccaag
 0 ACACAGUG m7b Created no TS -0.187000 -1.960000
hsa-miR-520a-5p aaactcaCTCTGGAccaag
 0 CUCCAGAG m7b Disrupted -0.194000 no TS No effect
hsa-miR-525-5p aaactcaCTCTGGAccaag
 0 CUCCAGAG m7b Disrupted -0.184000 no TS No effect
hsa-miR-5586-3p aaacTCACTCTGgaccaag
 0 CAGAGUGA m8a Disrupted -0.134000 no TS No effect
hsa-miR-759 aaactCACTCTGgaccaag
 0 GCAGAGUG m7b Disrupted -0.320000 -0.109000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809312G>T COSN1080036 TCGA-B5-A0JY-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5692b gaagataaATATTATTtga
 0 AAUAAUAU m8a Created no TS -0.040000 1.090000
hsa-miR-5692c gaagataaATATTATTtga
 0 AAUAAUAU m8a Created no TS -0.040000 0.390000
hsa-miR-5692b gaagataaATATTATTtga
 0 AAUAAUAU m8a Created no TS -0.04 1.09
hsa-miR-5692c gaagataaATATTATTtga
 0 AAUAAUAU m8a Created no TS -0.04 0.39

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809324G>A COSN8355728 TCGA-FW-A3R5-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1238 cgccttGAGGAAGaagata
 0 CUUCCUCG m7a Disrupted NA NA No effect
hsa-miR-4778-3p cgccttgagGAAGAAGAta
 0 UCUUCUUC m8a (m8a->m7a) -1.425000 -1.245000 No effect
hsa-miR-513c-5p cgcCTTGAGAAagaagata
 0 UUCUCAAG m8a Created no TS -0.231000 -1.700000
hsa-miR-514b-5p cgcCTTGAGAAagaagata
 0 UUCUCAAG m8a Created no TS -0.220000 -0.040000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809331C>T COSN513685 TCGA-GV-A3JZ-01 [urinary_tract][bladder][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3186-5p gcagaGACGCCTtgaggaa
 0 CAGGCGUC m7b Disrupted -0.326000 no TS 1.490000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809331T>T ICGC_64819 TCGA-GV-A3JZ-01A-11D-A21A-08 BladderUrothelialCarcinoma(TCGA,US)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3186-5p gcagaGACGCCTtgaggaa
 0 CAGGCGUC m7b Disrupted -0.326 no TS 1.49

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809332G>A COSN4894297 8062308 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3186-5p ggcagaGACGCCTtgagga
 0 CAGGCGUC m7b Disrupted -0.326000 no TS 2.520000
hsa-miR-4761-5p ggcagagaCACCTTGagga
 0 ACAAGGUG m7b Created -0.098000 -0.471000 -0.780000
hsa-miR-593-3p ggCAGAGACAccttgagga
 0 UGUCUCUG m8a (m7b->m8a) -0.353000 -0.521000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809334A>T COSN4894298 8013222 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3186-5p gtggcagaGACGCCTtgag
 0 CAGGCGUC m7b Disrupted -0.326000 no TS 3.910000
hsa-miR-4431 gtggcAGAGTCGCcttgag
 0 GCGACUCU m8a Created no TS -0.230000 No effect
hsa-miR-4522 gtggCAGAGTCgccttgag
 0 UGACUCUG m7b Created -0.292000 -0.391000 No effect
hsa-miR-593-3p gtggCAGAGACgccttgag
 0 UGUCUCUG m7b Disrupted -0.353000 -0.252000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809335G>A COSN8892748 TCGA-BR-8680-01 [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3186-5p agtggcagaGACGCCTtga
 0 CAGGCGUC m7b (m7b->m6b) -0.326000 no TS 6.200000
hsa-miR-5001-3p agtGGCAGAAacgccttga
 0 UUCUGCCU m7a (m6b->m7a) no TS -0.135000 No effect
hsa-miR-544a agtgGCAGAAacgccttga
 0 AUUCUGCA m6b Created -0.058000 -0.133000 -0.010000
hsa-miR-593-3p agtggCAGAGACgccttga
 0 UGUCUCUG m7b Disrupted -0.353000 -0.252000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809346A>T COSN8892749 TCGA-CD-A487-01 [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-412 tgagGGTGAAGagtggcag
 0 ACUUCACC m7b Disrupted -0.367000 -0.088000 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809348G>A COSN5025480 TCGA-EE-A29D-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3620 cttgAGGGTGAagagtggc
 0 UCACCCUG m7a Disrupted -0.156000 no TS 0.230000
hsa-miR-412 cttgagGGTGAAGagtggc
 0 ACUUCACC m7b Disrupted -0.367000 -0.088000 0.010000


Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809363G>T COSN4710412 TCGA-BS-A0UA-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809364C>T COSN5025481 TCGA-EE-A20C-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-145-3p aagAGGAATCgttgacctt
 0 GGAUUCCU m7b (m7b->m6c) -0.638000 -0.472000 No effect
hsa-miR-505-3p aagaggaatTGTTGACctt
 0 CGUCAACA m7b (m6b->m7b) no TS -0.199000 -1.650000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809368G>A COSN5025482 TCGA-FW-A3TU-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-145-3p ataaaagAGGAATCgttga
 0 GGAUUCCU m7b Disrupted -0.638000 -0.472000 No effect
hsa-miR-4753-3p ataAAAGAGAAatcgttga
 0 UUCUCUUU m8a Created no TS -0.260000 No effect
hsa-miR-4768-5p ataaaAGAGAAatcgttga
 0 AUUCUCUC m6b Created no TS -0.066000 No effect
hsa-miR-877-3p ataaAAGAGGAatcgttga
 0 UCCUCUUC m7a Disrupted -0.692000 -0.573000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809401T>C COSN2378371 TCGA-18-3409-01 [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-302a-5p ccatgattTTTAAGaaagt
 0 ACUUAAAC m6b Disrupted -0.024000 no TS 5.800000
hsa-miR-548c-3p ccatGATTTTTaagaaagt
 0 CAAAAAUC m7b Disrupted -0.048000 no TS 0.080000
hsa-miR-5680 ccatgATTTCTaagaaagt
 0 GAGAAAUG m6b Created no TS -0.011000 -1.540000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809406G>A COSN5025483 TCGA-GN-A266-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2681-3p attccCCATGATttttaag
 0 UAUCAUGG m7b Disrupted -0.206000 no TS 0.030000
hsa-miR-3115 attcCCCATAatttttaag
 0 AUAUGGGU m6b Created no TS -0.210000 -4.930000
hsa-miR-3675-5p attCCCCATAatttttaag
 0 UAUGGGGC m7a (m6b->m7a) no TS -0.235000 -0.930000
hsa-miR-548c-3p attccccatGATTTTTaag
 0 CAAAAAUC m7b (m7b->m6b) -0.048000 0.085000 0.070000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809418A>T COSN525992 TCGA-95-7039-01 [lung][right_upper_lobe][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-149-5p gaGAGCCAGAatattcccc
 0 UCUGGCUC m8a (m8a->m7b) -0.510000 -0.319000 No effect
hsa-miR-193a-3p gagaGCCAGTatattcccc
 0 AACUGGCC m6b Created no TS -0.197000 -2.280000
hsa-miR-193b-3p gagaGCCAGTatattcccc
 0 AACUGGCC m6b Created no TS -0.197000 -10.230000
hsa-miR-3064-5p gagAGCCAGAatattcccc
 0 UCUGGCUG m7a (m7a->m6b) -0.178000 no TS 0.220000
hsa-miR-4778-5p gagagcCAGAATattcccc
 0 AAUUCUGU m6b Disrupted -0.044000 no TS 0.010000
hsa-miR-4794 gagAGCCAGAatattcccc
 0 UCUGGCUA m7a (m7a->m6b) -0.183000 no TS 0.160000
hsa-miR-664-5p gagAGCCAGTatattcccc
 0 ACUGGCUA m7a (m6b->m7a) -0.189000 no TS 0.740000
hsa-miR-892b gagAGCCAGTatattcccc
 0 CACUGGCU m7b (m6c->m7b) no TS -0.443000 -0.950000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809434C>A COSN525990 TCGA-50-5946-02 [lung][right_upper_lobe][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2113 cataCACAAAatggaagag
 0 AUUUGUGC m6b Created no TS -0.066000 No effect
hsa-miR-4716-5p catacacAACATGGAagag
 0 UCCAUGUU m8a Disrupted -0.246000 no TS No effect
hsa-miR-5010-3p catACACAAAAtggaagag
 0 UUUUGUGU m8a Created no TS -0.226000 No effect
hsa-miR-599 catACACAACatggaagag
 0 GUUGUGUC m7a (m7a->m6b) no TS -0.086000 -0.590000
hsa-miR-2113 cataCACAAAatggaagag
 0 AUUUGUGC m6b Created no TS -0.066000 No effect
hsa-miR-4716-5p catacacAACATGGAagag
 0 UCCAUGUU m8a Disrupted -0.246000 no TS No effect
hsa-miR-5010-3p catACACAAAAtggaagag
 0 UUUUGUGU m8a Created no TS -0.226000 No effect
hsa-miR-599 catACACAACatggaagag
 0 GUUGUGUC m7a (m7a->m6b) no TS -0.086000 -0.590000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809435A>T COSN2379148 TCGA-50-5933-01 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4716-5p acatacacAACATGGAaga
 0 UCCAUGUU m8a Disrupted -0.246000 no TS No effect
hsa-miR-599 acatACACAACatggaaga
 0 GUUGUGUC m7a Disrupted NA NA 0.900000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809435A>G COSN8634583 TCGA-DU-5849-01 [central_nervous_system][brain][glioma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4716-5p acatacacAACATGGAaga
 0 UCCAUGUU m8a Disrupted -0.246000 no TS No effect
hsa-miR-5581-3p acatacacaGCATGGAAga
 0 UUCCAUGC m8a (m7a->m8a) -0.118000 -0.399000 -3.440000
hsa-miR-599 acatACACAACatggaaga
 0 GUUGUGUC m7a Disrupted NA NA -1.060000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809447C>T COSN2378370 TCGA-66-2773-01 [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-135b-3p gcagctgagCCTACATaca
 0 AUGUAGGG m7a (m7a->m6a) NA NA 9.240000
hsa-miR-24-3p gcagCTGAGCCtacataca
 0 UGGCUCAG m7b Disrupted -0.213000 no TS 0.670000
hsa-miR-3668 gcagctgagTCTACATaca
 0 AAUGUAGA m7b (m6b->m7b) -0.067000 -0.228000 -2.170000
hsa-miR-512-5p gcaGCTGAGTctacataca
 0 CACUCAGC m7b (m6c->m7b) no TS -0.225000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809449A>G COSN2378369 TCGA-18-3414-01 [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-24-3p cagcagCTGAGCCtacata
 0 UGGCUCAG m7b Disrupted -0.213000 no TS 0.680000
hsa-miR-4747-3p cagcagctGGGCCTacata
 0 AAGGCCCG m6b Created no TS -0.263000 -6.230000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809451T>A COSN2378368 TCGA-18-3414-01 [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-24-3p accagcagCTGAGCCtaca
 0 UGGCUCAG m7b Disrupted -0.213000 no TS 0.990000
hsa-miR-3194-3p accagcaGCAGAGCctaca
 0 AGCUCUGC m7b Created no TS -0.243000 -7.840000
hsa-miR-3692-5p accagCAGCAGagcctaca
 0 CCUGCUGG m6b Created -0.227000 -0.337000 -0.030000
hsa-miR-760 accagcagCAGAGCCtaca
 0 CGGCUCUG m7b Created -0.184000 -0.436000 -0.500000
hsa-miR-93-3p accagCAGCAGagcctaca
 0 ACUGCUGA m6b Created no TS -0.114000 -0.610000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809461C>A COSN409398 TCGA-B0-5120-01 [kidney][NS][carcinoma][clear_cell_renal_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1273g-5p tcgaaaAACCACCagcagc
 0 GGUGGUUG m7a Disrupted NA NA No effect
hsa-miR-138-5p tcgaaaaacCACCAGCagc
 0 AGCUGGUG m7b (m7b->m6b) -0.422000 -0.172000 0.030000
hsa-miR-29b-1-5p tcgaaaaacAACCAGCagc
 0 GCUGGUUU m7a (m6a->m7a) NA NA -2.840000
hsa-miR-323a-5p tcgaaaaACCACCagcagc
 0 AGGUGGUC m6b Disrupted -0.183000 no TS 0.020000
hsa-miR-323b-5p tcgaaaaACAACCagcagc
 0 AGGUUGUC m6b Created no TS -0.157000 -9.770000
hsa-miR-4299 tcgaaaaacCACCAGCagc
 0 GCUGGUGA m7a (m7a->m6a) NA NA 0.830000
hsa-miR-4456 tcgaaaaaCCACCAGcagc
 0 CCUGGUGG m7b Disrupted -0.286000 no TS 0.020000
hsa-miR-548q tcgaaaaacCACCAGCagc
 0 GCUGGUGC m7a (m7a->m6a) NA NA 1.580000
hsa-miR-876-3p tcgaaaAACCACCAgcagc
 0 UGGUGGUU m8a Disrupted -0.440000 no TS 6.510000


Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809465A>T COSN525989 TCGA-99-8032-01 [lung][right_upper_lobe][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809465A>C COSN8892750 TCGA-BR-8680-01 [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1273g-5p actatcgaaCAACCACCag
 0 GGUGGUUG m8a (m7a->m8a) no TS -0.214000 No effect
hsa-miR-323b-5p actatcgaACAACCaccag
 0 AGGUUGUC m6b Created no TS 0.000000 No effect
hsa-miR-375 actatCGAACAAccaccag
 0 UUUGUUCG m7b Created -0.079000 0.000000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.53809469C>T COSN8355729 TCGA-FS-A1ZZ-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1305 tgtaactaTTGAAAAacca
 0 UUUUCAAC m7a Created no TS 0.000000 No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
53808694 rs193186244 T T hsa-miR-106a-5p
hsa-miR-106b-5p
hsa-miR-17-5p
hsa-miR-20a-5p
hsa-miR-20b-5p
hsa-miR-3973
hsa-miR-519d-3p
hsa-miR-520g-3p
hsa-miR-520h
hsa-miR-526b-3p
hsa-miR-93-5p
4
4
4
4
4
1
4
1
1
4
4
 GCACTTTga
GCACTTTga
GCACTTTga
GCACTTTga
GCACTTTga
gcACTTTGA
GCACTTTga
gCACTTTGA
gCACTTTGA
GCACTTTga
GCACTTTga
 Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
N
N
N
N
N
N
 -0.156
-0.156
-0.156
-0.156
-0.156
-0.04
-0.156
-0.196
-0.196
-0.156
-0.156
53808767 rs139441645 G
A hsa-miR-133a-5p
hsa-miR-138-5p
hsa-miR-4728-3p
hsa-miR-5007-3p
hsa-miR-6131
1
1
2
2
1
 ACCAGCAtatgac
ACCAGCAtatgac
acCAGCATAtgac
accagCATATGAc
ACCAGCAtatgac
 Created
Created
Created
Created
Created
N
N
N
N
N
 -0.2
-0.163
-0.133
-0.067
-0.151
53808849 rs34535738 - - 0
A hsa-miR-5003-3p
11
 tgGAAAAGTgagga
 Unknown
N
 0.006
53808870 rs140554743 C
T hsa-miR-320a
hsa-miR-320b
hsa-miR-320c
hsa-miR-320d
hsa-miR-4429
7
7
7
7
7
 CAGCTTTggtgga
CAGCTTTggtgga
CAGCTTTggtgga
CAGCTTTggtgga
CAGCTTTggtgga
 Created
Created
Created
Created
Created
N
N
N
N
N
 -0.091
-0.091
-0.091
-0.091
-0.1
53808913 rs190515330 G G hsa-miR-3127-5p
hsa-miR-6823-5p
1
1
 gaCCCTGAAgctc
gACCCTGAagctc
 Disrupted
Disrupted
N
N
 -0.115
-0.146
A hsa-miR-1178-5p
hsa-miR-1182
hsa-miR-2909
1
1
1
 GACCCTAaagctc
GACCCTAaagctc
gaCCCTAAAgctc
 Created
Created
Created
N
N
N
 -0.165
-0.19
-0.101
53808914 rs182175548 T T hsa-miR-1182
hsa-miR-3127-5p
hsa-miR-6823-5p
21
21
21
 AGACCCTgaagct
agaCCCTGAAgct
agACCCTGAagct
 Disrupted
Disrupted
Disrupted
N
N
N
 -0.167
-0.12
-0.146
C hsa-miR-6727-5p
21
 agaCCCCGAAgct
 Created
N
 -0.227
53809118 rs16937768 A A hsa-miR-4659a-3p
hsa-miR-4659b-3p
8
8
 AGAAGAAtcggaa
AGAAGAAtcggaa
 Disrupted
Disrupted
N
N
 -0.004
-0.004
C hsa-miR-6740-3p
hsa-miR-924
8
9
 AGAAGACtcggaa
agAAGACTCggaa
 Created
Created
N
N
 -0.073
-0.084
53809134 rs181269166 C C hsa-miR-363-5p
hsa-miR-4651
hsa-miR-608
hsa-miR-6745
hsa-miR-6782-5p
hsa-miR-6798-5p
2
2
2
2
1
8
 gtTCCACCCctga
gttCCACCCCtga
gttCCACCCCtga
gtTCCACCCctga
gttcCACCCCTga
gttccaCCCCTGA
 Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
N
 -0.177
-0.245
-0.245
-0.195
-0.191
-0.153
G hsa-miR-3127-5p
hsa-miR-3652
hsa-miR-3918
hsa-miR-4430
hsa-miR-4446-3p
hsa-miR-4492
hsa-miR-4498
hsa-miR-5001-5p
hsa-miR-762
8
2
8
2
1
2
2
2
2
 gttccaGCCCTGA
gtTCCAGCCctga
gttccaGCCCTGA
gtTCCAGCCctga
gttcCAGCCCTga
gttCCAGCCCtga
gttCCAGCCCtga
gttCCAGCCCtga
gttCCAGCCCtga
 Created
Created
Created
Created
Created
Created
Created
Created
Created
N
N
N
N
N
N
N
N
N
 -0.285
-0.141
-0.14
-0.141
-0.157
-0.23
-0.221
-0.239
-0.221
53809212 rs11003863 A A hsa-miR-4494
hsa-miR-4778-3p
hsa-miR-499b-5p
11
11
11
 aagaagAGTCTGA
AAGAAGAgtctga
aagaagAGTCTGA
 Disrupted
Disrupted
Disrupted
N
N
N
 -0.109
-0.121
-0.112
C hsa-miR-103a-2-5p
11
 AAGAAGCgtctga
 Created
N
 -0.085
53809363 rs150023169 G
A hsa-miR-145-3p
hsa-miR-580-5p
2
2
 GGAATCAttgacc
ggAATCATTgacc
 Created
Created
N
N
 -0.168
-0.004
53809396 rs200863026 A A hsa-miR-302a-5p
13
 TTTAAGAaagtta
 Disrupted
N
 -0.024
53809442 rs16937769 A A hsa-miR-223-5p
hsa-miR-297
hsa-miR-3668
hsa-miR-567
hsa-miR-6806-5p
hsa-miR-7852-3p
8
8
4
8
4
4
 gcctacATACACA
gcctACATACAca
gcCTACATAcaca
gcctACATACAca
GCCTACAtacaca
gcCTACATAcaca
 Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
N
 -0.098
-0.125
-0.067
-0.066
-0.2
-0.079
C hsa-miR-196a-5p
hsa-miR-196b-5p
hsa-miR-3927-3p
hsa-miR-6831-5p
4
4
4
4
 gcCTACCTAcaca
gcCTACCTAcaca
gcCTACCTAcaca
gcCTACCTAcaca
 Created
Created
Created
Created
N
N
N
N
 -0.137
-0.14
-0.124
-0.124
53809447 rs145418788 C C hsa-miR-24-3p
hsa-miR-6806-5p
8
4
 gCTGAGCCtacat
gctgaGCCTACAt
 Disrupted
Disrupted
N
N
 -0.213
-0.2
T hsa-miR-3668
hsa-miR-512-5p
4
6
 gctgagTCTACAT
GCTGAGTctacat
 Created
Created
N
N
 -0.161
-0.225
53809469 rs12359240 C
T hsa-miR-1305
hsa-miR-335-3p
hsa-miR-6826-5p
3
3
3
 aactaTTGAAAAa
aactatTGAAAAA
aaCTATTGAaaaa
 Created
Created
Created
N
N
N
 No Change
No Change
No Change

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