SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
  Home Search Help Download  

PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001130141
Gene Symbol: PCBP3
Description: Homo sapiens poly(rC) binding protein 3 (PCBP3), transcript variant 2, mRNA.
Gene Location: chr21(+):47269874-47362368
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr21:g.45941768G>A COSN8315640 TCGA-BH-A18G-01 [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-574-5p ccggctctCACACTCtgta
 0 UGAGUGUG m7b Created no TS -0.124000 -0.440000

Mutation Mutation ID Sample Name Cancer Type
chr21:g.45942397C>T COSN1894214 RK022_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-221-5p gcacagacgTGCCAGGgag
 0 ACCUGGCA m7b (m6c->m7b) -0.124000 -0.273000 No effect
hsa-miR-4634 gcacagaCGCGCCagggag
 2
 CGGCGCGA m6b Disrupted -0.258000 no TS 1.080000
hsa-miR-564 gcacagaCGTGCCagggag
 0 AGGCACGG m6b Created no TS -0.175000 -3.270000
hsa-miR-221-5p gcacagacgTGCCAGGgag
 0 ACCUGGCA m7b (m6c->m7b) -0.124000 -0.273000 No effect
hsa-miR-4634 gcacagaCGCGCCagggag
 2
 CGGCGCGA m6b Disrupted -0.258000 no TS 1.080000
hsa-miR-564 gcacagaCGTGCCagggag
 0 AGGCACGG m6b Created no TS -0.175000 -3.270000
hsa-miR-221-5p gcacagacgTGCCAGGgag
 0 ACCUGGCA m7b (m6c->m7b) -0.124 -0.273 No effect
hsa-miR-4634 gcacagaCGCGCCagggag
 2
 CGGCGCGA m6b Disrupted -0.258 no TS 1.08
hsa-miR-564 gcacagaCGTGCCagggag
 0 AGGCACGG m6b Created no TS -0.175 -3.27

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
45942397 rs140120987 C C hsa-miR-4634
2
 cagaCGCGCCAgg
 Disrupted
N
 -0.258
T hsa-miR-221-5p
hsa-miR-564
hsa-miR-8073
2
2
2
 cagacgTGCCAGG
cagaCGTGCCAgg
cagacgTGCCAGG
 Created
Created
Created
N
N
N
 -0.149
-0.175
-0.121

Genome Browser