SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_012387
Gene Symbol: PADI4
Description: Homo sapiens peptidyl arginine deiminase, type IV (PADI4), mRNA.
Gene Location: chr1(+):17634689-17690495
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr1:g.17363771C>T COSN15032912 LP6005409-DNA_H01 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1197 cttccctgGTGTCCTctcc
 0 UAGGACAC m7b Created no TS -0.102000 -2.970000
hsa-miR-4733-3p cttcCCTGGTGtcctctcc
 0 CCACCAGG m7b Created no TS 0.000000 No effect
hsa-miR-5004-5p cttccctggTGTCCTCtcc
 0 UGAGGACA m7b (m6c->m7b) no TS -0.108000 -4.250000

Mutation Mutation ID Sample Name Cancer Type
chr1:g.17363798C>G COSN9366996 C0061T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1280 cagatgtCGGTGGGtcctc
 0 UCCCACCG m7b Created no TS -0.239000 -4.430000
hsa-miR-3683 cagATGTCGCtgggtcctc
 1
 UGCGACAU m7b (m7b->m6b) -0.206000 no TS 4.630000


Mutation Mutation ID Sample Name Cancer Type
chr1:g.17363826A>T COSN1093083 BN13T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr1:g.17363936C>T COSN1414655 RK037_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3619-3p aacATGGTCCtagcactgc
 0 GGGACCAU m7b (m7b->m6b) -0.203000 no TS 3.090000
hsa-miR-3667-5p aacatGGTCTTagcactgc
 0 AAAGACCC m6b Created no TS -0.125000 -1.760000
hsa-miR-4639-5p aacatggtCTTAGCActgc
 0 UUGCUAAG m7b Created no TS -0.149000 -0.460000
hsa-miR-548ao-3p aacatGGTCTTagcactgc
 0 AAAGACCG m6b Created no TS -0.151000 -1.780000
hsa-miR-591 aaCATGGTCTtagcactgc
 0 AGACCAUG m8a (m7a->m8a) -0.217000 -0.244000 -0.140000
hsa-miR-3619-3p aacATGGTCCtagcactgc
 0 GGGACCAU m7b (m7b->m6b) -0.203 no TS 3.09
hsa-miR-3667-5p aacatGGTCTTagcactgc
 0 AAAGACCC m6b Created no TS -0.125 -1.76
hsa-miR-4639-5p aacatggtCTTAGCActgc
 0 UUGCUAAG m7b Created no TS -0.149 -0.46
hsa-miR-548ao-3p aacatGGTCTTagcactgc
 0 AAAGACCG m6b Created no TS -0.151 -1.78
hsa-miR-591 aaCATGGTCTtagcactgc
 0 AGACCAUG m8a (m7a->m8a) -0.217 -0.244 -0.14

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
17363796 rs201352794 C C hsa-miR-3683
1
 agATGTCGCtggg
 Disrupted
N
 -0.206

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