SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_176072
Gene Symbol: P2RY2
Description: Homo sapiens purinergic receptor P2Y, G-protein coupled, 2 (P2RY2), transcript variant 2, mRNA.
Gene Location: chr11(+):72929343-72947395
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr11:g.73235369C>G COSN1542512 RK052_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3144-5p cgccacagtGTCCCCagat
0 AGGGGACC m6b Created no TS -0.173000 1.100000
hsa-miR-3150a-3p cgccacagtCTCCCCAGat
5
CUGGGGAG m8a (m8a->m7b) -0.220000 no TS 0.610000
hsa-miR-3175 cgccacagTCTCCCCagat
5
CGGGGAGA m7b Disrupted -0.368000 no TS No effect
hsa-miR-4318 cgCCACAGTGtccccagat
0 CACUGUGG m8a (m7a->m8a) -0.139000 -0.139000 -0.250000
hsa-miR-4652-5p cgccacagtGTCCCCagat
0 AGGGGACU m6b Created no TS -0.181000 -0.020000
hsa-miR-873-3p cgccaCAGTCTCCccagat
1
GGAGACUG m8a Disrupted -0.220000 -0.084000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.73235574A>T COSN1137625 HCC134T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4661-5p ctcccatGCTAGTagctgg
0 AACUAGCU m6b Created no TS -0.112000 No effect
hsa-miR-5011-3p ctcCCATGCAagtagctgg
2
GUGCAUGG m7b (m7b->m6b) -0.255000 no TS 0.010000
hsa-miR-4661-5p ctcccatGCTAGTagctgg
0 AACUAGCU m6b Created no TS -0.112 No effect
hsa-miR-5011-3p ctcCCATGCAagtagctgg
2
GUGCAUGG m7b (m7b->m6b) -0.255 no TS 0.01

Mutation Mutation ID Sample Name Cancer Type
chr11:g.73235619T>A 10_16502 6408 Breast cancer
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3929 agtcCAGCCTaatcaagtc
6
GAGGCUGA m6b Disrupted -0.123 0 1.52
hsa-miR-4419b agtcCAGCCTaatcaagtc
6
GAGGCUGA m6b Disrupted -0.12 0 3.84
hsa-miR-4430 agTCCAGCCTaatcaagtc
3
AGGCUGGA m8a (m8a->m7a) -0.287 -0.436 No effect
hsa-miR-4478 agtcCAGCCTaatcaagtc
6
GAGGCUGA m6b Disrupted -0.116 0 3.65
hsa-miR-4505 agtCCAGCCTaatcaagtc
4
AGGCUGGG m7a (m7a->m6a) -0.244 -0.383 -2.09
hsa-miR-647 agtcCAGCCAaatcaagtc
6
GUGGCUGC m6b Created no TS -0.139 -0.03

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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