SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_005124 |
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Gene Symbol: | NUP153 |
Description: | Homo sapiens nucleoporin 153kDa (NUP153), mRNA. |
Gene Location: | chr6(-):17615268-17706818 |
Browse Associations |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr6:g.17615272T>A | COSN7788517 | PCSI_0080_Pa_P_526 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3658 |
ggaaaTCTTAAAaaaaaaa |
18 |
UUUAAGAA | m7a | Created | -0.137000 | -0.182000 |
-0.720000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr6:g.17615745G>A | COSN15385818 | 0006_CRUK_PC_0006_T2_DNA | [prostate][NS][carcinoma][adenocarcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr6:g.17616025G>A | COSN8871424 | SNUH_G10_S1 | [haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][acute_myeloid_leukaemia] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-142-5p |
ttgtACTTTATGctggggt |
0 | CAUAAAGU | m8a | Created | no TS | -0.034000 |
-1.380000 |
hsa-miR-338-3p |
ttgtactttATGCTGGggt |
0 | UCCAGCAU | m7b | (m6b->m7b) | no TS | -0.216000 |
-0.460000 |
hsa-miR-3973 |
ttgTACTTTGTgctggggt |
2 |
ACAAAGUA | m8a | Disrupted | -0.053000 | no TS |
1.300000 |
hsa-miR-5590-3p |
ttgtACTTTATgctggggt |
0 | AAUAAAGU | m7b | Created | no TS | -0.053000 |
-1.170000 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
17615272 | rs201954304 | T | |||||||
A |
hsa-miR-3658 hsa-miR-7856-5p |
0 |
aaTCTTAAAaaaa aatCTTAAAAaaa |
Created Created |
N N |
-0.045 -0.019 |
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17616025 | rs3777711 | G | G |
hsa-miR-3973 |
2 |
TACTTTGtgctgg |
Disrupted |
N |
-0.053 |
A |
hsa-miR-142-5p hsa-miR-338-3p hsa-miR-548a-5p hsa-miR-548ab hsa-miR-548ak hsa-miR-548am-5p hsa-miR-548ap-5p hsa-miR-548aq-5p hsa-miR-548ar-5p hsa-miR-548as-5p hsa-miR-548au-5p hsa-miR-548av-5p hsa-miR-548ay-5p hsa-miR-548b-5p hsa-miR-548c-5p hsa-miR-548d-5p hsa-miR-548h-5p hsa-miR-548i hsa-miR-548j-5p hsa-miR-548k hsa-miR-548l hsa-miR-548o-5p hsa-miR-548w hsa-miR-548y hsa-miR-559 hsa-miR-5590-3p hsa-miR-8054 |
2 14 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 |
tACTTTATgctgg tactttATGCTGG TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg TACTTTAtgctgg tACTTTATgctgg TACTTTAtgctgg |
Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created |
N N N N N N N N N N N N N N N N N N N N N N N N N N N |
-0.034 -0.216 -0.017 -0.01 -0.01 -0.01 -0.01 -0.01 -0.02 -0.01 -0.01 -0.127 -0.01 -0.01 -0.01 -0.01 -0.01 -0.01 -0.01 -0.127 -0.016 -0.01 -0.01 -0.01 -0.01 -0.053 -0.127 |