SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_001025433
Gene Symbol: NQO1
Description: Homo sapiens NAD(P)H dehydrogenase, quinone 1 (NQO1), transcript variant 1, mRNA.
Gene Location: chr16(-):69743303-69760533
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr16:g.69710066T>G ICGC_D455DF9C-2A78-11E2-951E-21FD496BB9B8 CPCG_0103_Pr_P_P5 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3165 caggcgtgATCCACCacac
0 AGGUGGAU m7b Disrupted -0.187 no TS -0.11
hsa-miR-4284 caggcGTGAGCCaccacac
0 GGGCUCAC m7b Created no TS -0.176 -0.89

Mutation Mutation ID Sample Name Cancer Type
chr16:g.69710284G>A ICGC_401533 TCGA-AA-3510-01A-01D-1408-10 ColonAdenocarcinoma(TCGA,US)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-144-5p tggtgTGATATCggctcac
0 GGAUAUCA m7b Created no TS 0.013 -0.02

Mutation Mutation ID Sample Name Cancer Type
chr16:g.69710363T>C COSN7269424 8016470 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1255a gcagTCATCCacttttttt
0 AGGAUGAG m6b Created no TS -0.120000 -5.360000
hsa-miR-1255b-5p gcagTCATCCacttttttt
0 CGGAUGAG m6b Created no TS -0.120000 -6.660000
hsa-miR-3681-5p gcagtcATCCACTtttttt
0 UAGUGGAU m7b Created no TS -0.198000 -1.180000
hsa-miR-3691-5p gcagtCATCCACTtttttt
6
AGUGGAUG m8a Created -0.222000 -0.450000 -0.070000
hsa-miR-4796-3p gcagtcatCCACTTTtttt
0 UAAAGUGG m7b Created no TS -0.152000 No effect
hsa-miR-548n gcagtcatcTACTTTTttt
0 CAAAAGUA m7b (m7b->m6b) -0.021000 no TS -0.010000
hsa-miR-548t-5p gcagtcatcCACTTTTttt
0 CAAAAGUG m7b (m6b->m7b) no TS -0.053000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr16:g.69710800T>C COSN6092835 RK181_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1245a tcttatGATCACTatcatg
0 AAGUGAUC m7b Created no TS -0.394000 -0.160000
hsa-miR-154-3p tctTATGATTactatcatg
5
AAUCAUAC m7a (m7a->m6b) -0.108000 -0.108000 No effect
hsa-miR-487a tctTATGATTactatcatg
5
AAUCAUAC m7a (m7a->m6b) -0.101000 -0.101000 -0.040000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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