SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001160109
Gene Symbol: NOS3
Description: Homo sapiens nitric oxide synthase 3 (endothelial cell) (NOS3), transcript variant 1, mRNA.
Gene Location: chr7(+):150690891-150701023
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Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr7:g.151003714G>T COSN8515975 4537_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-143-5p ctctagaACTGCACCtaga
 0 GGUGCAGU m8a Created no TS -0.199000 -7.370000
hsa-miR-3168 ctcTAGAACTgcacctaga
 0 GAGUUCUA m7b (m6b->m7b) no TS 0.000000 No effect
hsa-miR-4277 ctctAGAACTGCacctaga
 0 GCAGUUCU m8a Created no TS 0.000000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr7:g.151003897G>A COSN6594734 ICGC_MB82 [central_nervous_system][brain][primitive_neuroectodermal_tumour-medulloblastoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-129-1-3p ttccaggtcAGGGCTatta
 0 AAGCCCUU m6b Created no TS -0.228000 0.150000
hsa-miR-129-2-3p ttccaggtcAGGGCTatta
 0 AAGCCCUU m6b Created no TS -0.228000 0.150000
hsa-miR-3661 ttCCAGGTCAgggctatta
 2
 UGACCUGG m8a (m7a->m8a) -0.242000 -0.469000 -0.410000
hsa-miR-4323 ttccaggtcGGGGCTatta
 2
 CAGCCCCA m6b Disrupted -0.246000 no TS 10.220000
hsa-miR-4687-5p ttccaggtcAGGGCTatta
 0 CAGCCCUC m6b Created no TS -0.217000 -7.970000
hsa-miR-4732-3p ttccagGTCAGGGCtatta
 0 GCCCUGAC m8a Created no TS -0.232000 -0.510000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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