SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_006167
Gene Symbol: NKX3-1
Description: Homo sapiens NK3 homeobox 1 (NKX3-1), transcript variant 1, mRNA.
Gene Location: chr8(-):23536205-23540450
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr8:g.23678735->A cosmic_v64_1870281 NA [upper_aerodigestive_tract][mouth][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5007-3p tgcaaCATATGAgtgtttt
 0 AUCAUAUG m7b Disrupted -0.211000 no TS 8.270000

Mutation Mutation ID Sample Name Cancer Type
chr8:g.23680215G>A COSN2269976 RK006_C02 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1269a ttcattttAGTCCAGattt
 6
 CUGGACUG m7a Disrupted 0.035000 0.035000 No effect
hsa-miR-1269b ttcattttAGTCCAGattt
 6
 CUGGACUG m7a Disrupted 0.035000 0.035000 No effect
hsa-miR-378a-3p ttcattttAGTCCAGattt
 2
 ACUGGACU m7b Disrupted -0.587000 -0.353000 0.050000
hsa-miR-378b ttcattttAGTCCAGattt
 2
 ACUGGACU m7b Disrupted -0.566000 -0.332000 0.220000
hsa-miR-378c ttcattttAGTCCAGattt
 2
 ACUGGACU m7b Disrupted -0.587000 -0.353000 0.670000
hsa-miR-378d ttcattttAGTCCAGattt
 2
 ACUGGACU m7b Disrupted -0.587000 -0.353000 0.170000
hsa-miR-378e ttcattttAGTCCAGattt
 2
 ACUGGACU m7b Disrupted -0.587000 -0.353000 0.140000
hsa-miR-378f ttcattttAGTCCAGattt
 2
 ACUGGACU m7b Disrupted -0.587000 -0.332000 3.100000
hsa-miR-378h ttcattttAGTCCAGattt
 2
 ACUGGACU m7b Disrupted -0.576000 -0.342000 No effect
hsa-miR-378i ttcattttAGTCCAGattt
 2
 ACUGGACU m7b Disrupted -0.587000 -0.353000 0.090000
hsa-miR-422a ttcattttAGTCCAGattt
 2
 ACUGGACU m7b Disrupted -0.576000 -0.342000 No effect
hsa-miR-4638-3p ttcattttaGTCCAGattt
 2
 CCUGGACA m6b Disrupted -0.271000 -0.167000 No effect
hsa-miR-4782-5p ttcattttaATCCAGAttt
 2
 UUCUGGAU m7b (m6b->m7b) -0.092000 -0.237000 -0.290000
hsa-miR-5706 ttcattttaATCCAGAttt
 2
 UUCUGGAU m7b (m6b->m7b) -0.086000 -0.240000 -1.310000
hsa-miR-1269a ttcattttAGTCCAGattt
 0 CUGGACUG m7a Disrupted 0.035 0.035 No effect
hsa-miR-1269b ttcattttAGTCCAGattt
 0 CUGGACUG m7a Disrupted 0.035 0.035 No effect
hsa-miR-378a-3p ttcattttAGTCCAGattt
 0 ACUGGACU m7b Disrupted -0.587 -0.353 0.05
hsa-miR-378b ttcattttAGTCCAGattt
 0 ACUGGACU m7b Disrupted -0.566 -0.332 0.22
hsa-miR-378c ttcattttAGTCCAGattt
 0 ACUGGACU m7b Disrupted -0.587 -0.353 0.67
hsa-miR-378d ttcattttAGTCCAGattt
 0 ACUGGACU m7b Disrupted -0.587 -0.353 0.17
hsa-miR-378e ttcattttAGTCCAGattt
 0 ACUGGACU m7b Disrupted -0.587 -0.353 0.14
hsa-miR-378f ttcattttAGTCCAGattt
 0 ACUGGACU m7b Disrupted -0.587 -0.332 3.1
hsa-miR-378h ttcattttAGTCCAGattt
 0 ACUGGACU m7b Disrupted -0.576 -0.342 No effect
hsa-miR-378i ttcattttAGTCCAGattt
 0 ACUGGACU m7b Disrupted -0.587 -0.353 0.09
hsa-miR-422a ttcattttAGTCCAGattt
 0 ACUGGACU m7b Disrupted -0.576 -0.342 No effect
hsa-miR-4638-3p ttcattttaGTCCAGattt
 0 CCUGGACA m6b Disrupted -0.271 -0.167 No effect
hsa-miR-4782-5p ttcattttaATCCAGAttt
 0 UUCUGGAU m7b (m6b->m7b) -0.092 -0.237 -0.29
hsa-miR-5706 ttcattttaATCCAGAttt
 0 UUCUGGAU m7b (m6b->m7b) -0.086 -0.24 -1.31


Mutation Mutation ID Sample Name Cancer Type
chr8:g.23680407A>T COSN1362893 HX5T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr8:g.23681114A>T COSN6599613 ICGC_MB60 [central_nervous_system][brain][primitive_neuroectodermal_tumour-medulloblastoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1179 gcacaccAATGCTattgga
 0 AAGCAUUC m6b Created no TS -0.066000 -2.850000
hsa-miR-9-5p gcacACCAAAGctattgga
 2
 UCUUUGGU m7b Disrupted -0.087000 no TS 3.810000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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