| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_001079668 |
|---|---|
| Gene Symbol: | NKX2-1 |
| Description: | Homo sapiens NK2 homeobox 1 (NKX2-1), transcript variant 1, mRNA. |
| Gene Location: | chr14(-):36985603-36989430 |
| Browse Associations | |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr14:g.36516686T>C | COSN8588601 | J10_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-452-5p |
ccgcgaAAACAGTTtgttt |
0 | AACUGUUU | m8a | Created | no TS | -0.099000 |
-0.290000 |
| hsa-miR-4676-3p |
ccgcgaAAACAGTttgttt |
0 | CACUGUUU | m7b | Created | no TS | -0.071000 |
-0.280000 |
| hsa-miR-548g-3p |
ccgcgaaaACAGTTTgttt |
0 | AAAACUGU | m7b | Created | no TS | -0.072000 |
-0.020000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr14:g.36516862G>T | COSN1646236 | RK042_C01 | [liver][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-5580-5p |
actctGCCAGCAaagagga |
11 |
UGCUGGCU | m7a | Disrupted | -0.150000 | no TS |
-0.320000 |
| hsa-miR-5580-5p |
actctGCCAGCAaagagga |
11 |
UGCUGGCU | m7a | Disrupted | -0.150000 | no TS |
-0.320000 |
| hsa-miR-5580-5p |
actctGCCAGCAaagagga |
11 |
UGCUGGCU | m7a | Disrupted | -0.150000 | no TS |
-0.320000 |
| hsa-miR-5580-5p |
actctGCCAGCAaagagga |
0 | UGCUGGCU | m7a | Disrupted | -0.15 | no TS |
-0.32 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr14:g.36517080G>T | COSN15206490 | SM-4AX84 | [oesophagus][NS][carcinoma][adenocarcinoma] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-548ac |
aaatttgtgGGTTTTTttt |
19 |
CAAAAACC | m7b | (m7b->m6b) | -0.092000 | 0.033000 |
1.710000 |
| hsa-miR-548as-3p |
aaatttgtGGGTTTTtttt |
0 | UAAAACCC | m7b | Disrupted | -0.331000 | -0.092000 |
3.710000 |
| hsa-miR-548d-3p |
aaatttgtgGGTTTTTttt |
19 |
CAAAAACC | m7b | (m7b->m6b) | -0.083000 | 0.033000 |
-2.230000 |
| hsa-miR-548h-3p |
aaatttgtgGGTTTTTttt |
19 |
CAAAAACC | m7b | (m7b->m6b) | -0.083000 | 0.033000 |
-2.490000 |
| hsa-miR-548z |
aaatttgtgGGTTTTTttt |
19 |
CAAAAACC | m7b | (m7b->m6b) | -0.083000 | 0.033000 |
-2.490000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr14:g.36517158G>A | COSN5207695 | SS6003133 | [oesophagus][NS][carcinoma][adenocarcinoma] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-4799-5p |
cctggccgcATTTAGAcca |
0 | AUCUAAAU | m7b | (m6b->m7b) | no TS | 0.041000 |
-1.180000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr14:g.36517190C>A | COSN1167302 | HCC6T | [liver][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-432-5p |
gctgCTCCAAGcgcttcga |
0 | UCUUGGAG | m7b | Created | no TS | -0.087000 |
-12.520000 |
| hsa-miR-518e-3p |
gctgctccaAGCGCTTcga |
0 | AAAGCGCU | m7b | (m6b->m7b) | no TS | -0.266000 |
-1.290000 |
| hsa-miR-432-5p |
gctgCTCCAAGcgcttcga |
0 | UCUUGGAG | m7b | Created | no TS | -0.087000 |
-12.520000 |
| hsa-miR-518e-3p |
gctgctccaAGCGCTTcga |
0 | AAAGCGCU | m7b | (m6b->m7b) | no TS | -0.266000 |
-1.290000 |
| hsa-miR-432-5p |
gctgCTCCAAGcgcttcga |
0 | UCUUGGAG | m7b | Created | no TS | -0.087000 |
-12.520000 |
| hsa-miR-518e-3p |
gctgctccaAGCGCTTcga |
0 | AAAGCGCU | m7b | (m6b->m7b) | no TS | -0.266000 |
-1.290000 |
| hsa-miR-432-5p |
gctgCTCCAAGcgcttcga |
0 | UCUUGGAG | m7b | Created | no TS | -0.087 |
-12.52 |
| hsa-miR-518e-3p |
gctgctccaAGCGCTTcga |
0 | AAAGCGCU | m7b | (m6b->m7b) | no TS | -0.266 |
-1.29 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr14:g.36517208C>- | cosmic_v64_1767225 | NA | [upper_aerodigestive_tract][mouth][carcinoma][squamous_cell_carcinoma] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-1193 |
cacagaccACCATCCaccg |
0 | GGGAUGGU | m7b | Disrupted | -0.282000 | no TS |
15.750000 |
| hsa-miR-323a-5p |
cacaGACCACCatccaccg |
0 | AGGUGGUC | m7b | Disrupted | -0.460000 | no TS |
13.530000 |
| hsa-miR-3691-5p |
cacagaccaCATCCACcg |
0 | AGUGGAUG | m7b | (m6b->m7b) | -0.090000 | -0.123000 |
0.040000 |
| hsa-miR-432-3p |
cacagaccaCCATCCAccg |
0 | CUGGAUGG | m7b | (m7b->m6b) | -0.242000 | -0.111000 |
1.830000 |
| hsa-miR-4764-5p |
cacagacCACATCCAccg |
0 | UGGAUGUG | m8a | Created | no TS | -0.270000 |
-9.040000 |