SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_031419
Gene Symbol: NFKBIZ
Description: Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (NFKBIZ), transcript variant 2, mRNA.
Gene Location: chr3(+):101568357-101579869
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr3:g.101859483A>C COSN6711213 RK144_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5010-3p tttctatgACACAAAcata
2
UUUUGUGU m7b Created -0.039000 -0.176000 -0.020000
hsa-miR-592 tttctaTGACACAAacata
0 UUGUGUCA m8a Created no TS -0.410000 -0.400000
hsa-miR-597 tttctaTGACACAaacata
0 UGUGUCAC m7a Created no TS -0.174000 No effect
hsa-miR-599 tttctatGACACAAacata
0 GUUGUGUC m7b Created no TS -0.377000 -0.010000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.101859802C>T COSN6711214 RK190_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1915-3p gccttagtCCCTGGGagtt
0 CCCCAGGG m7b Disrupted -0.378000 no TS 0.300000
hsa-miR-211-3p gccttaGTCCCTGggagtt
2
GCAGGGAC m7b Disrupted -0.199000 no TS 0.020000
hsa-miR-4685-5p gccttagtCCCTGGGagtt
0 CCCAGGGC m7a Disrupted NA NA No effect
hsa-miR-4726-3p gccttagtcCCTGGGagtt
0 ACCCAGGU m6b Disrupted -0.134000 no TS 0.120000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.101860145A>T COSN1264171 HX15T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-330-3p ttctcaTGCTTTGaaatta
5
GCAAAGCA m7b Created -0.098000 -0.261000 -0.010000
hsa-miR-4422 ttctcATGCTTTgaaatta
0 AAAAGCAU m7b Created -0.059000 -0.108000 0.140000
hsa-miR-5700 ttctcATGCATTgaaatta
5
UAAUGCAU m7b Disrupted -0.041000 no TS 0.070000
hsa-miR-607 ttctcatgcTTTGAAatta
6
GUUCAAAU m6b Created -0.022000 0.043000 No effect
hsa-miR-330-3p ttctcaTGCTTTGaaatta
0 GCAAAGCA m7b Created -0.098 -0.261 -0.01
hsa-miR-4422 ttctcATGCTTTgaaatta
0 AAAAGCAU m7b Created -0.059 -0.108 0.14
hsa-miR-5700 ttctcATGCATTgaaatta
5
UAAUGCAU m7b Disrupted -0.041 no TS 0.07
hsa-miR-607 ttctcatgcTTTGAAatta
0 GUUCAAAU m6b Created -0.022 0.043 No effect

Mutation Mutation ID Sample Name Cancer Type
chr3:g.101860440A>G ICGC_72D285AE-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-338-3p tctcccaaaATGCTGGgat
0 UCCAGCAU m7b (m7b->m6c) -0.137 no TS -0.29
hsa-miR-4310 tctcccaaAATGCTGggat
0 GCAGCAUU m7b Disrupted -0.033 no TS 0.01

Mutation Mutation ID Sample Name Cancer Type
chr3:g.101860591A>G COSN1902056 RK062_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1305 aaagtcagtGTTGAAAcat
2
UUUUCAAC m7b (m6c->m7b) -0.097000 -0.153000 -1.020000
hsa-miR-141-3p aaagtCAGTGTTgaaacat
0 UAACACUG m7b Created no TS -0.146000 -4.983000
hsa-miR-200a-3p aaagtCAGTGTTgaaacat
0 UAACACUG m7b Created no TS -0.146000 -2.670000
hsa-miR-200b-3p aaagtCAGTATTgaaacat
1
UAAUACUG m7b Disrupted -0.106000 no TS -0.170000
hsa-miR-200c-3p aaagtCAGTATTgaaacat
1
UAAUACUG m7b Disrupted -0.106000 no TS -0.170000
hsa-miR-421 aaagtcagTGTTGAaacat
2
AUCAACAG m6b Created -0.312000 -0.376000 -0.890000
hsa-miR-429 aaagtCAGTATTgaaacat
1
UAAUACUG m7b Disrupted -0.106000 no TS -0.120000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.101860650A>C COSN8346974 0006_CRUK_PC_0006_T3_DNA [prostate][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-410 tgatgttTTATATatatca
1
AAUAUAAC m6b Disrupted -0.066000 -0.069000 1.950000
hsa-miR-5011-5p tgatgtttTATATATAtca
1
UAUAUAUA m8a Disrupted -0.187000 -0.019000 No effect
hsa-miR-570-3p tgaTGTTTTCtatatatca
0 CGAAAACA m7b (m6b->m7b) -0.017000 -0.123000 No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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