SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001174087
Gene Symbol: NCOA3
Description: Homo sapiens nuclear receptor coactivator 3 (NCOA3), transcript variant 3, mRNA.
Gene Location: chr20(+):46130600-46285621
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr20:g.47653902G>C COSN10016884 C0030T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1273g-3p tgtcCAGTGGaattggtga
 3
 ACCACUGC m6b Disrupted -0.130000 -0.022000 0.960000
hsa-miR-181a-2-3p tgtcCAGTGGaattggtga
 3
 ACCACUGA m6b Disrupted -0.146000 -0.030000 1.550000
hsa-miR-25-3p tgtccaGTGCAATtggtga
 19
 CAUUGCAC m7b Created -0.048000 -0.163000 No effect
hsa-miR-32-5p tgtccaGTGCAATtggtga
 19
 UAUUGCAC m7b Created -0.045000 -0.160000 No effect
hsa-miR-363-3p tgtccaGTGCAATTggtga
 19
 AAUUGCAC m8a Created -0.072000 -0.177000 No effect
hsa-miR-367-3p tgtccaGTGCAATTggtga
 19
 AAUUGCAC m8a Created -0.048000 -0.172000 -0.020000
hsa-miR-4436b-5p tgtccAGTGGAattggtga
 4
 GUCCACUU m6b Disrupted -0.078000 -0.001000 0.290000
hsa-miR-92a-3p tgtccaGTGCAATtggtga
 19
 UAUUGCAC m7b Created -0.051000 -0.147000 No effect
hsa-miR-92b-3p tgtccaGTGCAATtggtga
 19
 UAUUGCAC m7b Created -0.051000 -0.147000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr20:g.47654220C>T COSN5134330 PD3905a [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4789-3p ctacactTATGTGTtagac
 1
 CACACAUA m7b Created 0.196000 0.098000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr20:g.47654831T>G COSN1874296 RK041_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-126-5p agtccgaAATAATagcaat
 2
 CAUUAUUA m6b Disrupted 0.213000 no TS 0.050000
hsa-miR-26a-1-3p agtccgaaAGAATAGcaat
 3
 CCUAUUCU m7b Created 0.059000 0.080000 No effect
hsa-miR-26a-2-3p agtccgaaAGAATAGcaat
 3
 CCUAUUCU m7b Created 0.059000 0.080000 No effect
hsa-miR-4795-3p agtccgaAATAATAgcaat
 2
 AUAUUAUU m7b Disrupted 0.181000 no TS No effect
hsa-miR-126-5p agtccgaAATAATagcaat
 2
 CAUUAUUA m6b Disrupted 0.213000 no TS 0.050000
hsa-miR-26a-1-3p agtccgaaAGAATAGcaat
 3
 CCUAUUCU m7b Created 0.059000 0.080000 No effect
hsa-miR-26a-2-3p agtccgaaAGAATAGcaat
 3
 CCUAUUCU m7b Created 0.059000 0.080000 No effect
hsa-miR-4795-3p agtccgaAATAATAgcaat
 2
 AUAUUAUU m7b Disrupted 0.181000 no TS No effect
hsa-miR-126-5p agtccgaAATAATagcaat
 2
 CAUUAUUA m6b Disrupted 0.213 no TS 0.05
hsa-miR-26a-1-3p agtccgaaAGAATAGcaat
 0 CCUAUUCU m7b Created 0.059 0.08 No effect
hsa-miR-26a-2-3p agtccgaaAGAATAGcaat
 0 CCUAUUCU m7b Created 0.059 0.08 No effect
hsa-miR-4795-3p agtccgaAATAATAgcaat
 2
 AUAUUAUU m7b Disrupted 0.181 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr20:g.47654840T>G COSN1874298 RK182_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-219-2-3p taatagCAATTCatgggct
 2
 AGAAUUGU m6b Disrupted 0.062000 no TS 0.060000
hsa-miR-2964a-3p taataGCAATTCatgggct
 2
 AGAAUUGC m7b Disrupted -0.025000 no TS 2.710000
hsa-miR-302f taatAGCAATTcatgggct
 6
 UAAUUGCU m7b Disrupted 0.037000 0.024000 -0.340000
hsa-miR-219-2-3p taatagCAATTCatgggct
 2
 AGAAUUGU m6b Disrupted 0.062000 no TS 0.060000
hsa-miR-2964a-3p taataGCAATTCatgggct
 2
 AGAAUUGC m7b Disrupted -0.025000 no TS 2.710000
hsa-miR-302f taatAGCAATTcatgggct
 6
 UAAUUGCU m7b Disrupted 0.037000 0.024000 -0.340000

Mutation Mutation ID Sample Name Cancer Type
chr20:g.47655133A>C COSN1249728 HX17T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-151a-3p ccaCAGTCTAactgagcac
 2
 CUAGACUG m7b (m7b->m6b) 0.005000 no TS 0.420000
hsa-miR-3672 ccacAGTCTCActgagcac
 0 AUGAGACU m7b Created no TS 0.098000 -4.210000
hsa-miR-4276 ccacagtcTCACTGAGcac
 0 CUCAGUGA m8a Created no TS 0.063000 -0.670000
hsa-miR-4463 ccaCAGTCTCactgagcac
 2
 GAGACUGG m7a (m6a->m7a) 0.050000 no TS -0.010000
hsa-miR-5190 ccacagtcTCACTGagcac
 0 CCAGUGAC m6b Created no TS 0.057000 -0.680000
hsa-miR-873-3p ccaCAGTCTCactgagcac
 0 GGAGACUG m7b (m6b->m7b) no TS 0.019000 -0.560000
hsa-miR-935 ccacagtcTAACTGagcac
 7
 CCAGUUAC m6b Disrupted 0.184000 0.083000 No effect
hsa-miR-151a-3p ccaCAGTCTAactgagcac
 2
 CUAGACUG m7b (m7b->m6b) 0.005000 no TS 0.420000
hsa-miR-3672 ccacAGTCTCActgagcac
 0 AUGAGACU m7b Created no TS 0.098000 -4.210000
hsa-miR-4276 ccacagtcTCACTGAGcac
 0 CUCAGUGA m8a Created no TS 0.063000 -0.670000
hsa-miR-4463 ccaCAGTCTCactgagcac
 2
 GAGACUGG m7a (m6a->m7a) 0.050000 no TS -0.010000
hsa-miR-5190 ccacagtcTCACTGagcac
 0 CCAGUGAC m6b Created no TS 0.057000 -0.680000
hsa-miR-873-3p ccaCAGTCTCactgagcac
 0 GGAGACUG m7b (m6b->m7b) no TS 0.019000 -0.560000
hsa-miR-935 ccacagtcTAACTGagcac
 7
 CCAGUUAC m6b Disrupted 0.184000 0.083000 No effect
hsa-miR-151a-3p ccaCAGTCTAactgagcac
 2
 CUAGACUG m7b (m7b->m6b) 0.005 no TS 0.42
hsa-miR-3672 ccacAGTCTCActgagcac
 0 AUGAGACU m7b Created no TS 0.098 -4.21
hsa-miR-4276 ccacagtcTCACTGAGcac
 0 CUCAGUGA m8a Created no TS 0.063 -0.67
hsa-miR-4463 ccaCAGTCTCactgagcac
 2
 GAGACUGG m7a (m6a->m7a) 0.05 no TS -0.01
hsa-miR-5190 ccacagtcTCACTGagcac
 0 CCAGUGAC m6b Created no TS 0.057 -0.68
hsa-miR-873-3p ccaCAGTCTCactgagcac
 0 GGAGACUG m7b (m6b->m7b) no TS 0.019 -0.56
hsa-miR-935 ccacagtcTAACTGagcac
 0 CCAGUUAC m6b Disrupted 0.184 0.083 No effect

Mutation Mutation ID Sample Name Cancer Type
chr20:g.47655536C>T COSN4780692 tumor_4119027 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][Burkitt_lymphoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3616-3p tgagttTGCCCTCtttccc
 0 CGAGGGCA m7b Disrupted -0.158000 no TS 1.540000
hsa-miR-4311 tgagtttgcTCTCTTTCcc
 0 GAAAGAGA m8a (m7b->m8a) 0.266000 0.418000 -0.010000
hsa-miR-4470 tgaGTTTGCCctctttccc
 0 UGGCAAAC m7b (m7b->m6b) -0.106000 -0.064000 0.050000
hsa-miR-583 tgagtttgcCCTCTTTccc
 0 CAAAGAGG m7b (m7b->m6c) 0.096000 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr20:g.47656365A>G COSN8000142 PCSI_0083_Pa_P_526 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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