SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_002485 |
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Gene Symbol: | NBN |
Description: | Homo sapiens nibrin (NBN), mRNA. |
Gene Location: | chr8(-):90945563-90996899 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr8:g.89934415A>G | COSN2297487 | RK182_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-205-5p |
gggaaATGAAGGtcttttt |
1 |
UCCUUCAU | m7b | Disrupted | -0.047000 | no TS |
0.100000 |
hsa-miR-3667-5p |
gggaaatgaGGGTCTTTtt |
5 |
AAAGACCC | m8a | (m7a->m8a) | -0.047000 | -0.183000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr8:g.89935096T>A | 8_1304 | 667720 | Myeloid leukemia | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4775 |
gattaAAAATTAtaggaat |
4 |
UUAAUUUU | m7b | Disrupted | 0.183 | 0.194 |
0.13 |
hsa-miR-590-3p |
gattaAAAATTAtaggaat |
4 |
UAAUUUUA | m7a | Disrupted | 0.074 | no TS |
0.15 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr8:g.89935439A>G | COSN1369560 | BN28T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-148a-5p |
aaatgcacAGAACTTTgat |
0 | AAAGUUCU | m8a | Created | no TS | -0.141000 |
-0.010000 |
hsa-miR-148b-5p |
aaatgcaCAGAACTTtgat |
0 | AAGUUCUG | m8a | Created | no TS | -0.217000 |
-0.070000 |
hsa-miR-2113 |
aaatGCACAAAactttgat |
0 | AUUUGUGC | m7b | Disrupted | -0.354000 | no TS |
1.130000 |
hsa-miR-5008-3p |
aaatGCACAGaactttgat |
0 | CCUGUGCU | m6b | Created | no TS | -0.187000 |
-8.030000 |
hsa-miR-561-3p |
aaatgcacaAAACTTTGat |
2 |
CAAAGUUU | m8a | (m8a->m7a) | -0.160000 | -0.084000 |
0.020000 |
hsa-miR-148a-5p |
aaatgcacAGAACTTTgat |
0 | AAAGUUCU | m8a | Created | no TS | -0.141 |
-0.01 |
hsa-miR-148b-5p |
aaatgcaCAGAACTTtgat |
0 | AAGUUCUG | m8a | Created | no TS | -0.217 |
-0.07 |
hsa-miR-2113 |
aaatGCACAAAactttgat |
0 | AUUUGUGC | m7b | Disrupted | -0.354 | no TS |
1.13 |
hsa-miR-5008-3p |
aaatGCACAGaactttgat |
0 | CCUGUGCU | m6b | Created | no TS | -0.187 |
-8.03 |
hsa-miR-561-3p |
aaatgcacaAAACTTTGat |
0 | CAAAGUUU | m8a | (m8a->m7a) | -0.16 | -0.084 |
0.02 |