SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_002485
Gene Symbol: NBN
Description: Homo sapiens nibrin (NBN), mRNA.
Gene Location: chr8(-):90945563-90996899
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Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr8:g.89934415A>G COSN2297487 RK182_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-205-5p gggaaATGAAGGtcttttt
1
UCCUUCAU m7b Disrupted -0.047000 no TS 0.100000
hsa-miR-3667-5p gggaaatgaGGGTCTTTtt
5
AAAGACCC m8a (m7a->m8a) -0.047000 -0.183000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr8:g.89935096T>A 8_1304 667720 Myeloid leukemia
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4775 gattaAAAATTAtaggaat
4
UUAAUUUU m7b Disrupted 0.183 0.194 0.13
hsa-miR-590-3p gattaAAAATTAtaggaat
4
UAAUUUUA m7a Disrupted 0.074 no TS 0.15

Mutation Mutation ID Sample Name Cancer Type
chr8:g.89935439A>G COSN1369560 BN28T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-148a-5p aaatgcacAGAACTTTgat
0 AAAGUUCU m8a Created no TS -0.141000 -0.010000
hsa-miR-148b-5p aaatgcaCAGAACTTtgat
0 AAGUUCUG m8a Created no TS -0.217000 -0.070000
hsa-miR-2113 aaatGCACAAAactttgat
0 AUUUGUGC m7b Disrupted -0.354000 no TS 1.130000
hsa-miR-5008-3p aaatGCACAGaactttgat
0 CCUGUGCU m6b Created no TS -0.187000 -8.030000
hsa-miR-561-3p aaatgcacaAAACTTTGat
2
CAAAGUUU m8a (m8a->m7a) -0.160000 -0.084000 0.020000
hsa-miR-148a-5p aaatgcacAGAACTTTgat
0 AAAGUUCU m8a Created no TS -0.141 -0.01
hsa-miR-148b-5p aaatgcaCAGAACTTtgat
0 AAGUUCUG m8a Created no TS -0.217 -0.07
hsa-miR-2113 aaatGCACAAAactttgat
0 AUUUGUGC m7b Disrupted -0.354 no TS 1.13
hsa-miR-5008-3p aaatGCACAGaactttgat
0 CCUGUGCU m6b Created no TS -0.187 -8.03
hsa-miR-561-3p aaatgcacaAAACTTTGat
0 CAAAGUUU m8a (m8a->m7a) -0.16 -0.084 0.02

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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