SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_003826
Gene Symbol:	NAPG
Description:	Homo sapiens N-ethylmaleimide-sensitive factor attachment protein, gamma (NAPG), mRNA.
Gene Location:	chr18(+):10525872-10552766
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr18:g.10550599C>T			COSN6114021		RK308_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4803	tgttttTTATGTTtcattt	2	UAACAUAA	m7b	Created	-0.127000	-0.229000	-0.030000
hsa-miR-494	tgttttttATGTTTCAttt	2	UGAAACAU	m8a	Created	0.004000	-0.220000	-0.010000

Mutation			Mutation ID		Sample Name		Cancer Type
chr18:g.10551004G>T			9_36239		CRC-4-Tumor		Colorectal adenocarcinoma
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3613-3p	ttgTTTTTTGTtttttttt	0	ACAAAAAA	m8a	Disrupted	0.047	0	-0.24

Mutation			Mutation ID		Sample Name		Cancer Type
chr18:g.10551796A>G			COSN9325129		AOCS-120-3-6		[ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-5092	ggtgCGTGGATgttggtat	0	AAUCCACG	m7b	Disrupted	-0.046000	no TS	0.010000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
10551848	rs76649141	A	A	hsa-miR-3606-3p hsa-miR-513a-3p hsa-miR-513c-3p	4 4 4	AAATTTAatgttt AAATTTAatgttt AAATTTAatgttt	Disrupted Disrupted Disrupted	N N N	0.128 0.125 0.125
			T	hsa-miR-3163 hsa-miR-4282 hsa-miR-4803	4 4 5	aaATTTTATgttt AAATTTTAtgttt aaattTTATGTTt	Created Created Created	N N N	0.044 0.145 -0.036

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