SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_024953
Gene Symbol:	NAA25
Description:	Homo sapiens N(alpha)-acetyltransferase 25, NatB auxiliary subunit (NAA25), mRNA.
Gene Location:	chr12(-):112464492-112546635
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr12:g.112027398A>G			COSN8585371		J54_T		[lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3187-3p	tatgcagaaATGGCCAAta	15	UUGGCCAU	m8a	(m8a->m7a)	-0.367000	-0.156000	0.340000
hsa-miR-4252	tatgcagaAGTGGCCaata	0	GGCCACUG	m7a	Created	NA	NA	-0.040000
hsa-miR-4529-5p	tatgcagaaATGGCCaata	15	AGGCCAUC	m6b	Disrupted	-0.155000	no TS	0.650000
hsa-miR-4701-5p	tatgcagaaGTGGCCAAta	15	UUGGCCAC	m8a	(m7a->m8a)	-0.137000	-0.375000	-2.260000
hsa-miR-588	tatgcagaaGTGGCCAAta	15	UUGGCCAC	m8a	(m7a->m8a)	-0.134000	-0.365000	-2.350000

Mutation			Mutation ID		Sample Name		Cancer Type
chr12:g.112027981A>G			COSN5930506		RK212_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Mutation			Mutation ID		Sample Name		Cancer Type
chr12:g.112028632C>T			COSN8288799		PCSI_0083_Pa_P_526		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-223-5p	atatatATACACatatata	0	CGUGUAUU	m6b	Disrupted	-0.060000	no TS	0.020000
hsa-miR-3924	atatatatATACATATata	0	AUAUGUAU	m8a	Created	-0.141000	-0.237000	0.140000
hsa-miR-5011-5p	ataTATATATAcatatata	6	UAUAUAUA	m8a	Created	0.322000	0.235000	0.050000
hsa-miR-568	atatataTATACATatata	16	AUGUAUAA	m7a	Created	-0.174000	-0.174000	0.290000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
112027309	rs148633753	-	AT	hsa-miR-1277-5p hsa-miR-5011-5p hsa-miR-6507-5p	13 12 15	atATATATTcttaca aTATATATtcttaca atataTATTCTTAca	Unknown Unknown Unknown	N N N	-0.001 -0.069 0.009
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112027323	rs202157443	-	T	hsa-miR-190a-3p hsa-miR-5011-5p	21 21	aaaATATATAtat aaaaTATATATAt	Unknown Unknown	N N	-0.201 -0.108
			-	hsa-miR-126-5p hsa-miR-4795-3p hsa-miR-656-3p	21 21 21	aaAATAATAtat aaAATAATAtat aaaATAATATAt	Unknown Unknown Unknown	N N N	0.029 -0.08 -0.079
112028633	rs146516127	-	TA	hsa-miR-190a-3p hsa-miR-223-5p hsa-miR-5011-5p hsa-miR-511-3p	0	tATATATAcacatat tatatATACACAtat TATATATAcacatat tatataTACACATAt	Unknown Unknown Unknown Unknown	N N N N	-0.053 -0.004 -0.01 -0.001
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