| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_000431 |
|---|---|
| Gene Symbol: | MVK |
| Description: | Homo sapiens mevalonate kinase (MVK), transcript variant 1, mRNA. |
| Gene Location: | chr12(+):110011499-110035071 |
| Browse Associations | |
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| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr12:g.109596949G>A | COSN7309752 | 8066470 | [pancreas][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-425-3p |
tggTTCCCGAagaagtgtg |
0 | AUCGGGAA | m7b | (m6b->m7b) | no TS | -0.322000 |
-4.400000 |
| hsa-miR-4497 |
tggtTCCCGGAGaagtgtg |
1 |
CUCCGGGA | m8a | Disrupted | -0.473000 | -0.215000 | No effect |
| hsa-miR-4778-3p |
tggttcccGAAGAAGtgtg |
0 | UCUUCUUC | m7b | Created | no TS | -0.015000 |
-0.330000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr12:g.109597155G>A | COSN1556969 | RK061_C01 | [liver][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-1280 |
ccggaggCGGTGGGcctgg |
0 | UCCCACCG | m7b | Disrupted | -0.506000 | -0.357000 |
2.480000 |
| hsa-miR-1281 |
ccGGAGGCGAtgggcctgg |
1 |
UCGCCUCC | m8a | (m7a->m8a) | -0.376000 | -0.627000 |
-0.030000 |