SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001044393
Gene Symbol: MUC1
Description: Homo sapiens mucin 1, cell surface associated (MUC1), transcript variant 2, mRNA.
Gene Location: chr1(-):155158299-155162706
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr1:g.155186170A>C ICGC_1288982 TCGA-AX-A0J0-01A-11D-A117-09 UterineCorpusEndometrioidCarcinoma(TCGA,US)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3650 tcttacACACACCcagcag
 0 AGGUGUGU m7b Created no TS -0.189 -12.63
hsa-miR-4455 tcttacaCACACCCagcag
 0 AGGGUGUG m7b Created no TS -0.411 -6.54
hsa-miR-5010-3p tcttACACAAAcccagcag
 0 UUUUGUGU m7b Disrupted -0.018 no TS 4.13
hsa-miR-5087 tcttacACAAACCCagcag
 0 GGGUUUGU m8a Disrupted -0.113 no TS 7.38
hsa-miR-599 tcttACACAAacccagcag
 0 GUUGUGUC m6b Disrupted -0.03 no TS -1.41
hsa-miR-609 tcttacacACACCCagcag
 0 AGGGUGUU m6b Created no TS -0.152 -1.81

Mutation Mutation ID Sample Name Cancer Type
chr1:g.155187241G>A ICGC_ssm_v3_8619 BN24T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
155186174 rs11465209 C C hsa-miR-5010-3p
hsa-miR-599
3
3
 ctcttACACAAAc
ctcttACACAAAc
 Disrupted
Disrupted
N
N
 -0.018
-0.03
T hsa-miR-3149
hsa-miR-568
3
2
 ctcttATACAAAc
ctcTTATACAAac
 Created
Created
N
N
 0.017
-0.061

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