SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_021090
Gene Symbol: MTMR3
Description: Homo sapiens myotubularin related protein 3 (MTMR3), transcript variant 3, mRNA.
Gene Location: chr22(+):30279157-30426857
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr22:g.30026049->T ICGC_ssm_v3_5277 BN15T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr22:g.30026338C>T COSN8997261 8069337 [pancreas][NS][carcinoid-endocrine_tumour][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4700-3p tcccTCCTGTGaggagctg
 1
 CACAGGAC m7a Created -0.031000 -0.031000 No effect
hsa-miR-4722-5p tccCTCCTGCgaggagctg
 0 GGCAGGAG m7b (m7b->m6b) -0.263000 -0.189000 0.250000
hsa-miR-513a-5p tccctCCTGTGAggagctg
 0 UUCACAGG m7b Created no TS -0.045000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr22:g.30026471G>A COSN10029400 C0098T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4749-3p gcaggcGAGGGGCtgggag
 0 CGCCCCUC m7b Disrupted -0.348000 -0.227000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr22:g.30027189A>G COSN1897052 RK052_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3177-3p ggggagGCCGTGCttgact
 9
 UGCACGGC m7b Created -0.213000 -0.322000 -0.020000

Mutation Mutation ID Sample Name Cancer Type
chr22:g.30028196G>C COSN15585972 C0084T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-15a-5p tttttagcTGCTGCTctga
 8
 UAGCAGCA m7b Disrupted -0.597000 -0.602000 0.010000
hsa-miR-15b-5p tttttagcTGCTGCTctga
 8
 UAGCAGCA m7b Disrupted -0.600000 -0.615000 No effect
hsa-miR-16-5p tttttagcTGCTGCTctga
 8
 UAGCAGCA m7b Disrupted -0.579000 -0.594000 No effect
hsa-miR-195-5p tttttagcTGCTGCTctga
 8
 UAGCAGCA m7b Disrupted -0.580000 -0.595000 No effect
hsa-miR-28-5p tttttAGCTCCTgctctga
 2
 AAGGAGCU m7b Created -0.073000 -0.087000 No effect
hsa-miR-3139 tttttAGCTCCTgctctga
 2
 UAGGAGCU m7b Created -0.080000 -0.122000 No effect
hsa-miR-4633-3p ttttTAGCTCCTgctctga
 0 AGGAGCUA m8a Created no TS -0.041000 -2.180000
hsa-miR-4722-5p tttttagCTCCTGCtctga
 0 GGCAGGAG m7b Created -0.263000 -0.263000 0.310000
hsa-miR-610 tttTTAGCTCctgctctga
 2
 UGAGCUAA m7b (m6b->m7b) 0.044000 0.055000 -0.540000
hsa-miR-646 tttttAGCTGCTgctctga
 8
 AAGCAGCU m7b Disrupted -0.497000 -0.471000 0.120000
hsa-miR-708-5p tttttAGCTCCTgctctga
 2
 AAGGAGCU m7b Created -0.093000 -0.135000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr22:g.30029188T>A COSN5990807 RK136_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3938 tagAGGGAATTtggtctga
 1
 AAUUCCCU m8a Disrupted 0.150000 0.085000 No effect
hsa-miR-4446-5p tagAGGGAAATtggtctga
 0 AUUUCCCU m8a Created 0.171000 0.267000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr22:g.30030632A>G COSN1260674 HX16T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4313 tcagcgaggAGGGGGCggg
 0 AGCCCCCU m7b (m7b->m6c) -0.412000 -0.285000 -1.270000
hsa-miR-4667-3p tcagcgAGGAGGGggcggg
 0 UCCCUCCU m7b Disrupted -0.186000 -0.116000 0.100000
hsa-miR-5193 tcagcGAGGAGGgggcggg
 2
 UCCUCCUC m7b Disrupted -0.068000 -0.018000 0.130000
hsa-miR-4313 tcagcgaggAGGGGGCggg
 0 AGCCCCCU m7b (m7b->m6c) -0.412 -0.285 -1.27
hsa-miR-4667-3p tcagcgAGGAGGGggcggg
 0 UCCCUCCU m7b Disrupted -0.186 -0.116 0.1
hsa-miR-5193 tcagcGAGGAGGgggcggg
 2
 UCCUCCUC m7b Disrupted -0.068 -0.018 0.13

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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