SomamiR DB

SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only All 6mer or longer seed matches

PolymiRTS Database

RefSeq ID:	NM_002451
Gene Symbol:	MTAP
Description:	Homo sapiens methylthioadenosine phosphorylase (MTAP), mRNA.
Gene Location:	chr9(+):21802634-21865969
Browse Associations
Browse Pathways

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.21862272A>C			COSN14695181		CHC433T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-193b-5p	gaaaaaAAACCCCaccatt	0	CGGGGUUU	m7b	Created	no TS	-0.329000	No effect
hsa-miR-3151	gaaaaaaaaCCCCACCatt	1	GGUGGGGC	m7a	(m6b->m7a)	-0.353000	-0.353000	No effect
hsa-miR-3170	gaaaaaaAACCCCAccatt	0	CUGGGGUU	m7b	Created	no TS	-0.198000	No effect
hsa-miR-4447	gaaaaaaaaCCCCACCatt	1	GGUGGGGG	m7a	(m6b->m7a)	-0.389000	-0.389000	No effect
hsa-miR-4472	gaaaaaaaaCCCCACCatt	1	GGUGGGGG	m7a	(m6b->m7a)	-0.389000	-0.389000	No effect
hsa-miR-92a-2-5p	gaaaaaaaaCCCCACCatt	1	GGGUGGGG	m7b	(m6c->m7b)	-0.511000	-0.826000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.21862898T>A			COSN14697974		CHC433T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-10a-3p	acagtGAATTTaatcaaat	1	CAAAUUCG	m6b	Disrupted	0.100000	0.071000	0.010000
hsa-miR-4760-3p	acagTGAATTTaatcaaat	0	AAAUUCAU	m7a	Disrupted	NA	NA	0.010000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.21863364G>T			ICGC_80A6CBCC-2A78-11E2-96E7-04FD496BB9B8		CPCG_0102_Pr_P_P1		ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-106a-5p	cccaGCACTTTgggaggcc	0	AAAAGUGC	m7b	Created	no TS	0.129	-0.03
hsa-miR-106b-5p	cccaGCACTTTgggaggcc	0	UAAAGUGC	m7b	Created	no TS	0.129	No effect
hsa-miR-128	cccagCACTGTGggaggcc	1	UCACAGUG	m7b	Disrupted	0.074	-0.035	0.09
hsa-miR-150-5p	cccagcactTTGGGAGgcc	0	UCUCCCAA	m7b	(m6c->m7b)	no TS	0.069	No effect
hsa-miR-17-5p	cccaGCACTTTGggaggcc	0	CAAAGUGC	m8a	Created	no TS	0.129	-0.03
hsa-miR-186-3p	cccagcaCTTTGGGaggcc	0	GCCCAAAG	m7b	Created	-0.114	-0.032	-0.01
hsa-miR-188-3p	cccagcacTGTGGGAGgcc	0	CUCCCACA	m8a	Disrupted	-0.481	-0.536	0.07
hsa-miR-20a-5p	cccaGCACTTTgggaggcc	0	UAAAGUGC	m7b	Created	no TS	0.138	-0.03
hsa-miR-20b-5p	cccaGCACTTTGggaggcc	0	CAAAGUGC	m8a	Created	no TS	0.138	-0.02
hsa-miR-302a-3p	cccAGCACTTtgggaggcc	0	UAAGUGCU	m7b	(m6b->m7b)	-0.042	0.076	No effect
hsa-miR-302b-3p	cccAGCACTTtgggaggcc	0	UAAGUGCU	m7b	(m6b->m7b)	-0.042	0.076	No effect
hsa-miR-302c-3p	cccAGCACTTtgggaggcc	0	UAAGUGCU	m7b	(m6b->m7b)	-0.042	0.076	No effect
hsa-miR-302d-3p	cccAGCACTTtgggaggcc	0	UAAGUGCU	m7b	(m6b->m7b)	-0.042	0.076	No effect
hsa-miR-302e	cccAGCACTTtgggaggcc	0	UAAGUGCU	m7b	(m6b->m7b)	-0.095	0.032	No effect
hsa-miR-3681-3p	cccagCACTGTGggaggcc	1	ACACAGUG	m7b	Disrupted	0.068	-0.041	0.04
hsa-miR-372	cccAGCACTTTgggaggcc	0	AAAGUGCU	m8a	Created	-0.042	0.057	0.11
hsa-miR-373-3p	cccAGCACTTtgggaggcc	0	GAAGUGCU	m7b	(m6b->m7b)	-0.032	0.067	-0.09
hsa-miR-512-3p	ccCAGCACTTtgggaggcc	0	AAGUGCUG	m8a	(m7a->m8a)	-0.023	-0.051	No effect
hsa-miR-519d	cccaGCACTTTGggaggcc	0	CAAAGUGC	m8a	Created	no TS	0.11	No effect
hsa-miR-520a-3p	cccAGCACTTTgggaggcc	0	AAAGUGCU	m8a	Created	-0.042	0.066	No effect
hsa-miR-520b	cccAGCACTTTgggaggcc	0	AAAGUGCU	m8a	Created	-0.032	0.067	No effect
hsa-miR-520c-3p	cccAGCACTTTgggaggcc	0	AAAGUGCU	m8a	Created	-0.032	0.067	No effect
hsa-miR-520d-3p	cccAGCACTTTgggaggcc	0	AAAGUGCU	m8a	Created	-0.042	0.076	No effect
hsa-miR-520e	cccAGCACTTTgggaggcc	0	AAAGUGCU	m8a	Created	-0.032	0.086	No effect
hsa-miR-520g	cccagCACTTTGggaggcc	0	ACAAAGUG	m7b	Created	no TS	0.17	No effect
hsa-miR-520h	cccagCACTTTGggaggcc	0	ACAAAGUG	m7b	Created	no TS	0.17	No effect
hsa-miR-526b-3p	cccaGCACTTTgggaggcc	0	GAAAGUGC	m7b	Created	no TS	0.11	No effect
hsa-miR-532-3p	cccagcactGTGGGAGGcc	0	CCUCCCAC	m8a	(m8a->m7b)	-0.173	-0.194	No effect
hsa-miR-93-5p	cccaGCACTTTGggaggcc	0	CAAAGUGC	m8a	Created	no TS	0.138	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.21863990G>C			COSN5700063		RK131_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-661	ctgaaCCCAGGCttctcta	2	UGCCUGGG	m7b	Disrupted	-0.096000	no TS	0.760000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.21864099G>A			COSN14698461		CHC433T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-129-5p	aggGCAAAAAtatgggcat	0	CUUUUUGC	m7b	(m6b->m7b)	0.415000	0.556000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.21864379C>T			COSN14683291		CHC433T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1277-5p	gctagTATATTaagtgaac	1	AAAUAUAU	m6b	Created	0.097000	0.266000	No effect
hsa-miR-374c-3p	gctagtataCTAAGTGaac	0	CACUUAGC	m7a	(m7a->m6b)	NA	NA	0.030000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.21864536A>G			COSN14694352		CHC433T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-410	tgctGTTATATTtggcatg	1	AAUAUAAC	m8a	Disrupted	0.122000	0.034000	-0.140000
hsa-miR-4803	tgctgTTATGTTtggcatg	0	UAACAUAA	m7b	Created	no TS	0.155000	-6.050000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.21864600G>T			COSN9705609		AOCS-120-3-6		[ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3619-3p	agggtcATGGTCCttgtga	2	GGGACCAU	m7b	Disrupted	0.001000	no TS	1.300000
hsa-miR-591	agggtCATGGTCcttgtga	2	AGACCAUG	m7b	Disrupted	-0.043000	-0.049000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.21865107T>C			COSN14935705		CHC433T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-421	caaatctcaTGTTGAattg	2	AUCAACAG	m6b	Disrupted	-0.107000	-0.117000	0.010000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.21865367T>C			ICGC_80A6D09A-2A78-11E2-96E7-04FD496BB9B8		CPCG_0102_Pr_P_P1		ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3680-5p	actGTGAGTCaattaaacc	0	GACUCACU	m7a	(m6a->m7a)	NA	NA	-0.49
hsa-miR-4798-3p	actGTGAGTTaattaaacc	0	AACUCACG	m7a	(m7a->m6a)	NA	NA	-0.34

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.21865843T>C			COSN14993495		CHC433T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-124-3p	gcttGTGCCTTttttattg	0	UAAGGCAC	m7b	Disrupted	-0.270000	no TS	0.650000
hsa-miR-506-3p	gcttGTGCCTTttttattg	0	UAAGGCAC	m7b	Disrupted	-0.260000	no TS	0.040000
hsa-miR-548an	gcttgTGCCTTTTttattg	0	AAAAGGCA	m8a	Disrupted	-0.258000	-0.114000	-0.030000
hsa-miR-5582-5p	gctTGTGCCTtttttattg	0	UAGGCACA	m7b	(m7b->m6b)	-0.264000	no TS	3.470000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.21865929C>G			COSN8520413		J90_T		[lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-105-5p	gaattttttGCATTTGAgg	2	UCAAAUGC	m8a	(m7b->m8a)	-0.069000	-0.337000	No effect
hsa-miR-3148	gaatTTTTTCCAtttgagg	1	UGGAAAAA	m8a	Disrupted	0.020000	0.226000	No effect
hsa-miR-3613-3p	gaaTTTTTTGcatttgagg	0	ACAAAAAA	m7b	(m6b->m7b)	no TS	-0.047000	No effect
hsa-miR-3688-3p	gaatttTTTCCATttgagg	2	UAUGGAAA	m7b	Disrupted	-0.201000	no TS	No effect
hsa-miR-4694-3p	gaatttttTCCATTTGagg	2	CAAAUGGA	m8a	Disrupted	-0.192000	no TS	9.620000
hsa-miR-548aw	gaattTTTTGCAtttgagg	2	GUGCAAAA	m7b	Created	-0.047000	-0.257000	-1.430000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.21865960A>C			COSN14704071		CHC433T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-2278	aaagCTGCTCTaagcatga	0	GAGAGCAG	m7b	Created	-0.007000	-0.421000	-0.130000
hsa-miR-4468	aaagCTGCTCTaagcatga	0	AGAGCAGA	m7a	Created	NA	NA	-0.010000
hsa-miR-4524a-5p	aaaGCTGCTATaagcatga	2	AUAGCAGC	m8a	Disrupted	-0.536000	-0.213000	0.200000
hsa-miR-4524b-5p	aaaGCTGCTATaagcatga	2	AUAGCAGC	m8a	Disrupted	-0.536000	-0.204000	0.240000

**Germline mutations in target sites of miRNAs in somatic mutation table**
Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
21862272	rs15735	-	A	hsa-miR-629-5p hsa-miR-6769a-5p hsa-miR-6769b-5p hsa-miR-6793-5p hsa-miR-6839-3p	0	aaaaAAACCCAcc aaaaaaACCCACC aaaaaaACCCACC aaaaaAACCCACc aaaaAAACCCAcc	Unknown Unknown Unknown Unknown Unknown	N N N N N	-0.106 -0.275 -0.247 -0.261 -0.205
21862272	rs15735	-	C	hsa-miR-193b-5p hsa-miR-3170 hsa-miR-6742-5p hsa-miR-6855-5p hsa-miR-92a-2-5p	0	aaaAAACCCCAcc aaaaAACCCCAcc aaaaaACCCCACc aaaaAACCCCAcc aaaaaaCCCCACC	Unknown Unknown Unknown Unknown Unknown	N N N N N	-0.329 -0.198 -0.301 -0.217 -0.315
21862671	rs146095448	T	T	hsa-miR-1468-3p hsa-miR-548aj-5p hsa-miR-548aw hsa-miR-548f-5p hsa-miR-548g-5p hsa-miR-548x-5p	2 2 2 2 2 2	tcctTTTTGCAta tcctTTTTGCAta tcctTTTTGCAta tcctTTTTGCAta tcctTTTTGCAta tcctTTTTGCAta	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N N	0.018 -0.002 -0.077 -0.002 -0.002 -0.002
21862671	rs146095448	T	C	hsa-miR-298	2	tcctTTCTGCAta	Created	N	-0.056
21862783	rs58147941	-	-	hsa-miR-129-5p hsa-miR-3149 hsa-miR-568	6 2 2	atataCAAAAAAa atATACAAAaaaa aTATACAAaaaaa	Unknown Unknown Unknown	N N N	0.005 0.002 0.003
21862783	rs58147941	-	A
21862898	rs1134871	A	T	hsa-miR-10a-3p	0	gtGAATTTAatca	Created	N	0.029
21862898	rs1134871	A	A	hsa-miR-6074	0	gTGAATATAatca	Disrupted	N	-0.014
21863044	rs112211340	T	T	hsa-miR-374b-3p hsa-miR-4524a-5p hsa-miR-4524b-5p	2 2 2	ttCTGCTAAAgaa ttCTGCTAAagaa ttCTGCTAAagaa	Disrupted Disrupted Disrupted	N N N	-0.136 -0.066 -0.066
21863044	rs112211340	T	C	hsa-miR-1271-5p hsa-miR-182-5p hsa-miR-6844 hsa-miR-7150 hsa-miR-9-5p hsa-miR-96-5p	2 2 1 2 1 2	ttcTGCCAAAgaa ttcTGCCAAAgaa ttctgcCAAAGAA ttCTGCCAAagaa ttctgCCAAAGAa ttcTGCCAAAgaa	Created Created Created Created Created Created	N N N N N N	-0.059 -0.054 0.052 -0.083 -0.005 -0.052
21863046	rs111342676	A	A	hsa-miR-374b-3p hsa-miR-4524a-5p hsa-miR-4524b-5p hsa-miR-4778-3p	2 2 2 2	CTGCTAAAgaaga CTGCTAAagaaga CTGCTAAagaaga ctgctaAAGAAGA	Disrupted Disrupted Disrupted Disrupted	N N N N	-0.136 -0.066 -0.066 0.044
21863046	rs111342676	A	G	hsa-miR-1251-5p hsa-miR-4684-5p hsa-miR-517-5p hsa-miR-942-5p	1 1 1 2	ctGCTAGAGAaga ctgcTAGAGAAga ctgCTAGAGAaga ctgctAGAGAAGA	Created Created Created Created	N N N N	-0.256 0.031 -0.042 -0.016
21863092	rs1134873	T	T	hsa-miR-4684-3p hsa-miR-518a-5p hsa-miR-527 hsa-miR-548aw	6 4 4 4	ttgggtTTGCAAC ttgggTTTGCAAc ttgggTTTGCAAc ttgggTTTGCAAc	Disrupted Disrupted Disrupted Disrupted	N N N N	-0.046 0.066 0.066 0.073
21863092	rs1134873	T	G	hsa-miR-8064	4	ttggGTGTGCAac	Created	N	-0.053
21863256	rs1134879	T	T	hsa-miR-548e-5p hsa-miR-548p	2 2	tttTGCTTTTtaa TTTTGCTttttaa	Disrupted Disrupted	N N	-0.016 -0.036
21863256	rs1134879	T	C	hsa-miR-548an	2	tttTGCCTTTtaa	Created	N	-0.1
21863623	rs11358276	-	A	hsa-miR-129-5p hsa-miR-3672 hsa-miR-6864-3p hsa-miR-8055 hsa-miR-873-3p	0	agtctCAAAAAAa AGTCTCAAaaaaa AGTCTCAAaaaaa agtCTCAAAAaaa AGTCTCAaaaaaa	Unknown Unknown Unknown Unknown Unknown	N N N N N	-0.001 -0.001 -0.001 -0.002 -0.001
21863623	rs11358276	-	-
21863623	rs56935102	-	AA	hsa-miR-129-5p hsa-miR-3672 hsa-miR-6864-3p hsa-miR-8055 hsa-miR-873-3p	0	cagtctCAAAAAAaa cAGTCTCAAaaaaaa cAGTCTCAAaaaaaa cagtCTCAAAAaaaa CAGTCTCAaaaaaaa	Unknown Unknown Unknown Unknown Unknown	N N N N N	-0.003 -0.002 -0.002 -0.004 -0.002
21863623	rs56935102	-	-
21864099	rs10117507	A	G	hsa-miR-5003-3p	0	gcAAAAGTAtggg	Created	N	0.174
21864099	rs10117507	A	A	hsa-miR-129-5p	0	GCAAAAAtatggg	Disrupted	N	0.141
21864379	rs10117550	T
21864379	rs10117550	T	T	hsa-miR-1277-5p hsa-miR-889-3p	0	agTATATTAagtg agtATATTAAgtg	Disrupted Disrupted	N N	0.169 0.174
21864536	rs3802394	G	A	hsa-miR-410-3p	0	tGTTATATttggc	Created	N	0.088
21864536	rs3802394	G	G	hsa-miR-4803	0	tgTTATGTTtggc	Disrupted	N	0.155
21864887	rs75664572	C	C	hsa-miR-541-3p hsa-miR-654-5p hsa-miR-6769a-5p hsa-miR-6769b-5p hsa-miR-92a-2-5p	1 1 1 1 1	cCCCACCAacacc cCCCACCAacacc cCCCACCAacacc cCCCACCAacacc CCCCACCAacacc	Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N	-0.068 -0.075 -0.071 -0.064 -0.174
21864887	rs75664572	C	T	hsa-miR-1296-3p hsa-miR-3152-3p hsa-miR-4460 hsa-miR-4694-5p hsa-miR-4727-3p	1 1 1 0 1	CCCCACTAacacc ccccaCTAACACc ccCCACTAAcacc ccccacTAACACC cCCCACTAAcacc	Created Created Created Created Created	N N N N N	-0.19 -0.063 -0.019 -0.047 -0.111
21864971	rs144453731	C	C	hsa-miR-302a-3p hsa-miR-302b-3p hsa-miR-302c-3p hsa-miR-302d-3p hsa-miR-302e hsa-miR-372-3p hsa-miR-373-3p hsa-miR-512-3p hsa-miR-519a-3p hsa-miR-519b-3p hsa-miR-519c-3p hsa-miR-520a-3p hsa-miR-520b hsa-miR-520c-3p hsa-miR-520d-3p hsa-miR-520e hsa-miR-5580-5p	3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 2	agccAGCACTTAt agccAGCACTTAt agccAGCACTTAt agccAGCACTTAt agccAGCACTTAt agccAGCACTTAt agccAGCACTTAt agcCAGCACTtat agccaGCACTTAt agccaGCACTTAt agccaGCACTTAt agccAGCACTTAt agccAGCACTTAt agccAGCACTTAt agccAGCACTTAt agccAGCACTTAt AGCCAGCActtat	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N N N N N N N N N N N N N	-0.042 -0.042 -0.042 -0.042 -0.095 -0.042 -0.032 -0.101 -0.015 -0.015 -0.015 -0.042 -0.032 -0.032 -0.042 -0.032 -0.282
21864971	rs144453731	C	T	hsa-miR-1278 hsa-miR-193a-3p hsa-miR-193b-3p hsa-miR-892b	3 2 2 2	agcCAGTACTtat aGCCAGTActtat aGCCAGTActtat AGCCAGTActtat	Created Created Created Created	N N N N	-0.074 -0.117 -0.117 -0.26
21865107	rs4977735	T	T	hsa-miR-421 hsa-miR-7159-5p	0	atctcaTGTTGAA atctcaTGTTGAA	Disrupted Disrupted	N N	0.01 0.021
21865107	rs4977735	T	C	hsa-miR-95-3p	0	atctcaCGTTGAA	Created	N	-0.111
21865158	rs148910202	G	G	hsa-miR-3156-3p hsa-miR-4301 hsa-miR-532-3p	2 2 2	ccAGTGGGAggta ccAGTGGGAggta ccaGTGGGAGgta	Disrupted Disrupted Disrupted	N N N	-0.032 -0.064 -0.089
21865158	rs148910202	G	A	hsa-miR-1304-3p hsa-miR-653-3p hsa-miR-6800-3p	2 2 2	cCAGTGAGAggta CCAGTGAgaggta ccagtGAGAGGTA	Created Created Created	N N N	-0.087 -0.025 -0.239
21865161	rs5896955	-	-	hsa-miR-4777-3p hsa-miR-532-3p	1 2	gtggGAGGTAAtt GTGGGAGgtaatt	Unknown Unknown	N N	-0.061 -0.026
21865161	rs5896955	-	G	hsa-miR-7848-3p	1	gtggGAGGGTAAtt	Unknown	N	-0.226
21865843	rs6475592	C	T	hsa-miR-124-3p hsa-miR-506-3p hsa-miR-548an hsa-miR-5582-5p	0	tGTGCCTTtttta tGTGCCTTtttta tgTGCCTTTttta TGTGCCTttttta	Created Created Created Created	N N N N	-0.27 -0.26 -0.144 -0.264
21865843	rs6475592	C
21865930	rs80226037	C	C	hsa-miR-105-5p hsa-miR-3148 hsa-miR-3688-3p hsa-miR-4694-3p hsa-miR-6124 hsa-miR-7853-5p	2 1 2 2 1 2	tttttcCATTTGA TTTTTCCAtttga ttTTTCCATttga ttttTCCATTTga tTTTTCCAtttga tttttcCATTTGA	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N N	-0.069 -0.206 -0.201 -0.192 -0.067 -0.062
21865930	rs80226037	C	T	hsa-miR-3121-3p hsa-miR-3671	2 2	ttttTCTATTTga tttttcTATTTGA	Created Created	N N	-0.163 -0.059
21865960	rs10965168	A	A	hsa-miR-15a-5p hsa-miR-15b-5p hsa-miR-16-5p hsa-miR-195-5p hsa-miR-424-5p hsa-miR-4524a-5p hsa-miR-4524b-5p hsa-miR-497-5p hsa-miR-503-5p hsa-miR-646 hsa-miR-6838-5p	2 2 2 2 2 2 2 2 2 2 2	GCTGCTAtaagca GCTGCTAtaagca GCTGCTAtaagca GCTGCTAtaagca GCTGCTAtaagca GCTGCTAtaagca GCTGCTAtaagca GCTGCTAtaagca GCTGCTAtaagca GCTGCTAtaagca GCTGCTAtaagca	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N N N N N N N	-0.218 -0.225 -0.225 -0.225 -0.232 -0.323 -0.332 -0.208 -0.256 -0.217 -0.218
21865960	rs10965168	A	C	hsa-miR-2278	2	gCTGCTCTAagca	Created	N	-0.414

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Somatic mutations that impact miRNA target sites

Germline mutations in target sites of miRNAs in somatic mutation table

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