SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_018000
Gene Symbol: MREG
Description: Homo sapiens melanoregulin (MREG), mRNA.
Gene Location: chr2(-):216807313-216878346
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr2:g.215943081A>G COSN15416498 AOCS-167-16-X [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1304-3p tatatacCAGTGAGctttt
 2
 UCUCACUG m7b Created -0.057000 -0.183000 -1.350000
hsa-miR-4774-5p tatATACCAGtgagctttt
 0 UCUGGUAU m7b (m6c->m7b) no TS -0.188000 -1.120000
hsa-miR-1304-3p tatatacCAGTGAGctttt
 2
 UCUCACUG m7b Created -0.057000 -0.183000 -1.350000
hsa-miR-4774-5p tatATACCAGtgagctttt
 0 UCUGGUAU m7b (m6c->m7b) no TS -0.188000 -1.120000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.215943295A>T 10_4462 6408 Breast cancer
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-127-5p tccAGCTTCAaaagttact
 13
 CUGAAGCU m7b (m7b->m6c) -0.156 no TS 0.04


Mutation Mutation ID Sample Name Cancer Type
chr2:g.215943693A>T COSN8983301 AOCS-153-1-2 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr2:g.215944025C>T COSN9229979 8057643 [pancreas][NS][carcinoid-endocrine_tumour][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3135b gcaCTCCAGCCtgggcgac
 2
 GGCUGGAG m8a Disrupted -0.093000 no TS -0.030000
hsa-miR-3652 gcacTCCAGCCtgggcgac
 2
 CGGCUGGA m7b Disrupted -0.043000 no TS No effect
hsa-miR-4430 gcacTCCAGCCTgggcgac
 2
 AGGCUGGA m8a Disrupted -0.043000 no TS No effect
hsa-miR-4463 gcactCCAGTCTgggcgac
 0 GAGACUGG m7b Created no TS -0.040000 No effect
hsa-miR-4494 gcactcCAGTCTGGgcgac
 0 CCAGACUG m8a Created no TS 0.005000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.215944300A>G COSN1824533 RK100_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1298 agatgtatCGAATGAtaga
 0 UUCAUUCG m7b Created no TS -0.157000 -1.200000
hsa-miR-382-3p agatgtatcGAATGATaga
 1
 AAUCAUUC m7b (m6b->m7b) -0.044000 -0.181000 -3.130000
hsa-miR-579 agatgtatCAAATGAtaga
 1
 UUCAUUUG m7b Disrupted -0.075000 no TS 0.390000
hsa-miR-644b-3p agatgtatCAAATGAtaga
 1
 UUCAUUUG m7b Disrupted -0.075000 no TS 0.100000
hsa-miR-1298 agatgtatCGAATGAtaga
 0 UUCAUUCG m7b Created no TS -0.157 -1.2
hsa-miR-382-3p agatgtatcGAATGATaga
 0 AAUCAUUC m7b (m6b->m7b) -0.044 -0.181 -3.13
hsa-miR-579 agatgtatCAAATGAtaga
 0 UUCAUUUG m7b Disrupted -0.075 no TS 0.39
hsa-miR-644b-3p agatgtatCAAATGAtaga
 0 UUCAUUUG m7b Disrupted -0.075 no TS 0.1

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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