SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_052845 |
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Gene Symbol: | MMAB |
Description: | Homo sapiens methylmalonic aciduria (cobalamin deficiency) cblB type (MMAB), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA. |
Gene Location: | chr12(-):109991520-110011358 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.109554285C>G | COSN8694267 | AOCS-168-1-8 | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-128 |
cagcccgCACTGTGgaagg |
3 |
UCACAGUG | m7b | Disrupted | -0.057000 | -0.044000 |
0.600000 |
hsa-miR-3681-3p |
cagcccgCACTGTGgaagg |
3 |
ACACAGUG | m7b | Disrupted | -0.026000 | -0.041000 |
0.470000 |
hsa-miR-4734 |
cagCCCGCAGtgtggaagg |
0 | GCUGCGGG | m7b | (m6c->m7b) | no TS | -0.218000 |
-4.700000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.109554346A>C | COSN5930006 | RK190_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1207-3p |
tccagagaCCAGCTGgcag |
0 | UCAGCUGG | m7b | Created | no TS | -0.113000 |
0.070000 |
hsa-miR-3663-5p |
tccagAGACCAGCtggcag |
2 |
GCUGGUCU | m8a | Created | -0.023000 | -0.096000 |
-0.010000 |
hsa-miR-593-3p |
tcCAGAGACAagctggcag |
2 |
UGUCUCUG | m8a | (m8a->m7b) | -0.161000 | -0.047000 |
0.140000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.109554994G>A | COSN8960111 | SS6003111 | [oesophagus][NS][carcinoma][adenocarcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3155a |
ggtgtcacAGCCTGGatgt |
0 | CCAGGCUC | m7a | Disrupted | NA | NA | No effect |
hsa-miR-3155b |
ggtgtcacAGCCTGGatgt |
0 | CCAGGCUC | m7a | Disrupted | NA | NA | No effect |
hsa-miR-4645-5p |
ggtgtcacaGCCTGGatgt |
1 |
ACCAGGCA | m6b | Disrupted | -0.091000 | -0.070000 | No effect |
hsa-miR-758 |
ggtGTCACAAcctggatgt |
1 |
UUUGUGAC | m7b | (m6c->m7b) | 0.013000 | 0.045000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.109555694G>A | COSN7309742 | 8015858 | [pancreas][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.109555869T>A | COSN4898211 | CPCG_0099_Pr_P_F0 | [prostate][NS][carcinoma][adenocarcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4426 |
cggCCATCTTtcttgctgg |
0 | GAAGAUGG | m7b | (m7b->m6c) | 0.094000 | no TS |
3.270000 |
hsa-miR-4647 |
cggCCATCTTtcttgctgg |
0 | GAAGAUGG | m7b | (m7b->m6c) | 0.094000 | no TS |
6.720000 |
hsa-miR-4662a-3p |
cggccatCTATCTTgctgg |
0 | AAAGAUAG | m7b | Created | no TS | 0.065000 |
-0.010000 |
hsa-miR-4662b |
cggCCATCTTTcttgctgg |
0 | AAAGAUGG | m8a | Disrupted | 0.094000 | no TS |
2.000000 |
hsa-miR-4426 |
cggCCATCTTtcttgctgg |
0 | GAAGAUGG | m7b | (m7b->m6c) | 0.094 | no TS |
3.27 |
hsa-miR-4647 |
cggCCATCTTtcttgctgg |
0 | GAAGAUGG | m7b | (m7b->m6c) | 0.094 | no TS |
6.72 |
hsa-miR-4662a-3p |
cggccatCTATCTTgctgg |
0 | AAAGAUAG | m7b | Created | no TS | 0.065 |
-0.01 |
hsa-miR-4662b |
cggCCATCTTTcttgctgg |
0 | AAAGAUGG | m8a | Disrupted | 0.094 | no TS |
2 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.109556261G>T | COSN7309743 | 8035316 | [pancreas][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-374a-3p |
tcagctTGATAAaatgagg |
0 | CUUAUCAG | m6b | Created | no TS | 0.060000 |
-0.150000 |
hsa-miR-513c-5p |
tcagCTTGAGAAaatgagg |
1 |
UUCUCAAG | m8a | Disrupted | -0.077000 | no TS |
0.020000 |
hsa-miR-514b-5p |
tcagCTTGAGAAaatgagg |
1 |
UUCUCAAG | m8a | Disrupted | -0.087000 | no TS |
0.270000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.109556543A>G | COSN15465122 | AOCS-171-1-0 | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3117-5p |
gtgctttaAGTGTCacatt |
2 |
AGACACUA | m6b | Created | -0.219000 | -0.326000 |
-0.240000 |
hsa-miR-489 |
gtgctttaaATGTCACatt |
0 | GUGACAUC | m7a | (m7a->m6a) | NA | NA |
0.030000 |
hsa-miR-3117-5p |
gtgctttaAGTGTCacatt |
2 |
AGACACUA | m6b | Created | -0.219000 | -0.326000 |
-0.240000 |
hsa-miR-489 |
gtgctttaaATGTCACatt |
0 | GUGACAUC | m7a | (m7a->m6a) | NA | NA |
0.030000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.109556564C>T | COSN1141777 | HX12T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-577 |
tgtgaTTTATCTgtgccaa |
0 | UAGAUAAA | m7b | Created | no TS | -0.018000 |
-0.230000 |
hsa-miR-577 |
tgtgaTTTATCTgtgccaa |
0 | UAGAUAAA | m7b | Created | no TS | -0.018 |
-0.23 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.109556603A>G | COSN5930007 | RK199_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-186-3p |
cagaTTTGGGatgggacca |
3 |
GCCCAAAG | m6b | Created | 0.072000 | 0.049000 |
-1.950000 |
hsa-miR-4733-5p |
cagatTTGGGATgggacca |
0 | AAUCCCAA | m7b | Created | no TS | -0.102000 |
-0.120000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.109556904C>A | COSN1141778 | HCC84T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1302 |
gcctttTGTCCCAgctcag |
10 |
UUGGGACA | m7b | Disrupted | -0.391000 | -0.164000 | No effect |
hsa-miR-150-3p |
gcctttTGTACCAGctcag |
0 | CUGGUACA | m8a | Created | no TS | -0.190000 | No effect |
hsa-miR-4298 |
gcctttTGTCCCAGctcag |
10 |
CUGGGACA | m8a | Disrupted | -0.382000 | -0.164000 | No effect |
hsa-miR-1302 |
gcctttTGTCCCAgctcag |
0 | UUGGGACA | m7b | Disrupted | -0.391 | -0.164 | No effect |
hsa-miR-150-3p |
gcctttTGTACCAGctcag |
0 | CUGGUACA | m8a | Created | no TS | -0.19 | No effect |
hsa-miR-4298 |
gcctttTGTCCCAGctcag |
0 | CUGGGACA | m8a | Disrupted | -0.382 | -0.164 | No effect |