SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_024101
Gene Symbol: MLPH
Description: Homo sapiens melanophilin (MLPH), transcript variant 2, mRNA.
Gene Location: chr2(+):238395877-238463961
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr2:g.237553617A>C COSN7800948 PCSI_0062_Pa_X [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3141 agacagagCCGCCCTgcac
 0 GAGGGCGG m7b Created no TS -0.254000 No effect
hsa-miR-4446-3p agacagagCAGCCCTGcac
 2
 CAGGGCUG m8a Disrupted -0.335000 -0.165000 No effect
hsa-miR-5691 agaCAGAGCAgccctgcac
 3
 UUGCUCUG m7b (m7b->m6b) -0.134000 no TS No effect
hsa-miR-760 agaCAGAGCCGccctgcac
 2
 CGGCUCUG m8a Created -0.078000 -0.285000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.237553681A>G COSN166443 GC8_T [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-let-7a-2-3p ctttccaCTGTACAcagtc
 0 CUGUACAG m7b Created no TS -0.141000 -0.120000
hsa-let-7g-3p ctttccaCTGTACAcagtc
 0 CUGUACAG m7b Created no TS -0.131000 -0.010000
hsa-miR-223-5p ctttccactATACACagtc
 0 CGUGUAUU m6b Disrupted -0.061000 no TS 5.620000
hsa-miR-3177-5p ctttccacTGTACACAgtc
 0 UGUGUACA m8a Created no TS -0.282000 -1.120000
hsa-miR-4460 ctttCCACTATacacagtc
 0 AUAGUGGU m7a Disrupted NA NA 0.010000
hsa-miR-4727-3p ctttCCACTATacacagtc
 0 AUAGUGGG m7a Disrupted NA NA 7.010000
hsa-let-7a-2-3p ctttccaCTGTACAcagtc
 0 CUGUACAG m7b Created no TS -0.141 -0.12
hsa-let-7g-3p ctttccaCTGTACAcagtc
 0 CUGUACAG m7b Created no TS -0.131 -0.01
hsa-miR-223-5p ctttccactATACACagtc
 0 CGUGUAUU m6b Disrupted -0.061 no TS 5.62
hsa-miR-3177-5p ctttccacTGTACACAgtc
 0 UGUGUACA m8a Created no TS -0.282 -1.12
hsa-miR-4460 ctttCCACTATacacagtc
 0 AUAGUGGU m7a Disrupted NA NA 0.01
hsa-miR-4727-3p ctttCCACTATacacagtc
 0 AUAGUGGG m7a Disrupted NA NA 7.01

Mutation Mutation ID Sample Name Cancer Type
chr2:g.237553860A>G COSN4991028 SS6003308 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-186-3p cttccCTTTGGGacaatgt
 0 GCCCAAAG m7b Created no TS -0.210000 -1.360000
hsa-miR-2355-3p cttccctttAGGACAATgt
 2
 AUUGUCCU m8a (m8a->m7b) -0.172000 no TS No effect
hsa-miR-4433-5p cttcccttTGGGACaatgt
 0 CGUCCCAC m6b Created no TS -0.167000 No effect
hsa-miR-4509 cttcCCTTTAGgacaatgt
 4
 ACUAAAGG m7b Disrupted -0.052000 0.048000 0.090000
hsa-miR-4646-3p cttccctttGGGACAATgt
 0 AUUGUCCC m8a (m7b->m8a) no TS -0.221000 -0.080000
hsa-miR-676-3p cttcccttTAGGACAatgt
 2
 CUGUCCUA m7b Disrupted -0.341000 no TS 1.620000
hsa-miR-186-3p cttccCTTTGGGacaatgt
 0 GCCCAAAG m7b Created no TS -0.210000 -1.360000
hsa-miR-2355-3p cttccctttAGGACAATgt
 2
 AUUGUCCU m8a (m8a->m7b) -0.172000 no TS No effect
hsa-miR-4433-5p cttcccttTGGGACaatgt
 0 CGUCCCAC m6b Created no TS -0.167000 No effect
hsa-miR-4509 cttcCCTTTAGgacaatgt
 4
 ACUAAAGG m7b Disrupted -0.052000 0.048000 0.090000
hsa-miR-4646-3p cttccctttGGGACAATgt
 0 AUUGUCCC m8a (m7b->m8a) no TS -0.221000 -0.080000
hsa-miR-676-3p cttcccttTAGGACAatgt
 2
 CUGUCCUA m7b Disrupted -0.341000 no TS 1.620000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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